Výsledky vyhledávání - "Maddalena Grieco"

Akademický článek

β-Hexachlorocyclohexane triggers neuroinflammatory activity, epigenetic histone post-translational modifications and cognitive dysfunction

Autor: Maddalena Grieco, Alessandra Giorgi, Giacomo Giacovazzo, Anna Maggiore, Serena Ficchì, Maria d'Erme, Luciana Mosca, Giuseppina Mignogna, Bruno Maras, Roberto Coccurello

Publikováno v: Ecotoxicology and Environmental Safety, Vol 279, Iss , Pp 116487- (2024)

Persistent organic pollutants (POPs), which encompass pesticides and industrial chemicals widely utilized across the globe, pose a covert threat to human health. β-hexachlorocyclohexane (β-HCH) is an organochlorine pesticide with striking stability

Externí odkaz: https://doaj.org/article/7cbd460452ff4c1683a3cc62d08e3dc0

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Akademický článek

Modulation of Methacrylated Hyaluronic Acid Hydrogels Enables Their Use as 3D Cultured Model

Autor: Ornella Ursini, Maddalena Grieco, Carla Sappino, Agostina Lina Capodilupo, Sara Maria Giannitelli, Emanuele Mauri, Alessio Bucciarelli, Chiara Coricciati, Valeria de Turris, Giuseppe Gigli, Lorenzo Moroni, Barbara Cortese

Publikováno v: Gels, Vol 9, Iss 10, p 801 (2023)

Bioengineered hydrogels represent physiologically relevant platforms for cell behaviour studies in the tissue engineering and regenerative medicine fields, as well as in in vitro disease models. Hyaluronic acid (HA) is an ideal platform since it is a

Externí odkaz: https://doaj.org/article/60a001596dfe422ca4f6f66b327dacf1

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Akademický článek

HYDRHA: Hydrogels of hyaluronic acid. New biomedical approaches in cancer, neurodegenerative diseases, and tissue engineering

Autor: Maddalena Grieco, Ornella Ursini, Ilaria Elena Palamà, Giuseppe Gigli, Lorenzo Moroni, Barbara Cortese

Publikováno v: Materials Today Bio, Vol 17, Iss , Pp 100453- (2022)

In the last decade, hyaluronic acid (HA) has attracted an ever-growing interest in the biomedical engineering field as a biocompatible, biodegradable, and chemically versatile molecule. In fact, HA is a major component of the extracellular matrix (EC

Externí odkaz: https://doaj.org/article/702987f6473348a7a2a0f256be13560c

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Akademický článek

Substrate stiffness effect on molecular crosstalk of epithelial-mesenchymal transition mediators of human glioblastoma cells

Autor: Bernadette Basilico, Ilaria Elena Palamà, Stefania D’Amone, Clotilde Lauro, Maria Rosito, Maddalena Grieco, Patrizia Ratano, Federica Cordella, Caterina Sanchini, Silvia Di Angelantonio, Davide Ragozzino, Mariafrancesca Cascione, Giuseppe Gigli, Barbara Cortese

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

The complexity of the microenvironment effects on cell response, show accumulating evidence that glioblastoma (GBM) migration and invasiveness are influenced by the mechanical rigidity of their surroundings. The epithelial–mesenchymal transition (E

Externí odkaz: https://doaj.org/article/0066cd94085f4006a75b8a5a260e0bf5

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Akademický článek

Neuroprotective Effects of PARP Inhibitors in Drosophila Models of Alzheimer’s Disease

Autor: Anna Maggiore, Assunta Maria Casale, Walter Toscanelli, Ugo Cappucci, Dante Rotili, Maddalena Grieco, Jean-Philippe Gagné, Guy G. Poirier, Maria d’Erme, Lucia Piacentini

Publikováno v: Cells, Vol 11, Iss 8, p 1284 (2022)

Alzheimer’s disease (AD) is an irreversible age-related neurodegenerative disorder clinically characterized by severe memory impairment, language deficits and cognitive decline. The major neuropathological hallmarks of AD include extracellular depo

Externí odkaz: https://doaj.org/article/d9116e09e0184c0386e791bb036e7ba2

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Akademický článek

Glucagon-Like Peptide-1: A Focus on Neurodegenerative Diseases

Autor: Maddalena Grieco, Alessandra Giorgi, Maria Cristina Gentile, Maria d’Erme, Susanna Morano, Bruno Maras, Tiziana Filardi

Publikováno v: Frontiers in Neuroscience, Vol 13 (2019)

Diabetes mellitus is one of the major risk factors for cognitive dysfunction. The pathogenesis of brain impairment caused by chronic hyperglycemia is complex and includes mitochondrial dysfunction, neuroinflammation, neurotransmitters’ alteration,

Externí odkaz: https://doaj.org/article/1801ea7f02f64e4fadf14f4611347e84

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HYDRHA

Autor: Maddalena Grieco, Ornella Ursini, Ilaria Elena Palamà, Giuseppe Gigli, Lorenzo Moroni, Barbara Cortese

Publikováno v: Materials today. Bio. 17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb87f78d4cb2e0d87e12be32a2b7281
https://doi.org/10.1016/j.mtbio.2022.100453

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ERp57 chaperon protein protects neuronal cells from Aβ-induced toxicity

Autor: Daniel Di Risola, Daniela Ricci, Ilaria Marrocco, Flavia Giamogante, Maddalena Grieco, Antonio Francioso, Aldrin Vasco‐Vidal, Patrizia Mancini, Gianni Colotti, Luciana Mosca, Fabio Altieri

Alzheimer's disease (AD) is a neurodegenerative disorder whose main pathological hallmark is the accumulation of Amyloid-β peptide (Aβ) in the form of senile plaques. Aβ can cause neurodegeneration and disrupt cognitive functions by several mechan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956658002e3b15f272bccf90c215be39
https://hdl.handle.net/10807/227167

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Fatty acid amide hydrolase (Faah) inhibition modulates amyloid-beta-induced microglia polarization

Autor: Maria Giovanna De Caris, Tiziana Bisogno, Roberto Coccurello, Maria D'Erme, Rita Businaro, Elisa Maggi, Federica Armeli, Patrizia Mancini, Mauro Maccarrone, Maddalena Grieco

Publikováno v: International journal of molecular sciences
22 (2021): 7711-1–7711-21. doi:10.3390/ijms22147711
info:cnr-pdr/source/autori:Grieco M.; De Caris M.G.; Maggi E.; Armeli F.; Coccurello R.; Bisogno T.; D'erme M.; Maccarrone M.; Mancini P.; Businaro R./titolo:Fatty acid amide hydrolase (Faah) inhibition modulates amyloid-beta-induced microglia polarization/doi:10.3390%2Fijms22147711/rivista:International journal of molecular sciences (Print)/anno:2021/pagina_da:7711-1/pagina_a:7711-21/intervallo_pagine:7711-1–7711-21/volume:22
International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences, Vol 22, Iss 7711, p 7711 (2021)

The ability of endocannabinoid (eCB) to change functional microglial phenotype can be explored as a possible target for therapeutic intervention. Since the inhibition of fatty acid amide hydrolase (FAAH), the main catabolic enzyme of anandamide (AEA)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75139ab3060630616e83b0e97c405b1
https://publications.cnr.it/doc/457269

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