Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Maddalena Di Sanzo"'
Autor:
Maddalena Di Sanzo, Flora Cozzolino, Anna Martina Battaglia, Ilenia Aversa, Vittoria Monaco, Alessandro Sacco, Flavia Biamonte, Camillo Palmieri, Francesca Procopio, Gianluca Santamaria, Francesco Ortuso, Piero Pucci, Maria Monti, Maria Concetta Faniello
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12987 (2022)
The H Ferritin subunit (FTH1), as well as regulating the homeostasis of intracellular iron, is involved in complex pathways that might promote or inhibit carcinogenesis. This function may be mediated by its ability to interact with different molecule
Externí odkaz:
https://doaj.org/article/4843d5ba45d5488aa0c59c5491b5b175
Autor:
Rosa Sottile, Giorgia Federico, Cinzia Garofalo, Rossana Tallerico, Maria Concetta Faniello, Barbara Quaresima, Costanza Maria Cristiani, Maddalena Di Sanzo, Gianni Cuda, Valeria Ventura, Arnika Kathleen Wagner, Gianluca Contrò, Nicola Perrotti, Elio Gulletta, Soldano Ferrone, Klas Kärre, Francesco Saverio Costanzo, Francesca Carlomagno, Ennio Carbone
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The ability of pathogens to sequester iron from their host cells and proteins affects their virulence. Moreover, iron is required for various innate host defense mechanisms as well as for acquired immune responses. Therefore, intracellular iron conce
Externí odkaz:
https://doaj.org/article/b4f9dadda2e54e4e84b4bc5b419386ae
Autor:
Maddalena Di Sanzo, Barbara Quaresima, Flavia Biamonte, Camillo Palmieri, Maria Concetta Faniello
Publikováno v:
Cells, Vol 9, Iss 12, p 2554 (2020)
Ferritin, the principal intracellular iron-storage protein localized in the cytoplasm, nucleus, and mitochondria, plays a major role in iron metabolism. The encoding ferritin genes are members of a multigene family that includes some pseudogenes. Eve
Externí odkaz:
https://doaj.org/article/6ecfbff5d695479b9e9b70a52ceb1b13
Autor:
Claudia Pileggi, Maddalena Di Sanzo, Valentina Mascaro, Maria Grazia Marafioti, Francesco Saverio Costanzo, Maria Pavia
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179016 (2017)
The role of serum ferritin (SF) as a prognostic factor has been analyzed in patients with myelodysplastic syndromes (MDS) who have undergone hematopoietic stem cell transplantation (HSCT), but the prognostic role of elevated SF levels is still contro
Externí odkaz:
https://doaj.org/article/97cdddfdf6bc4933b3d209e4eb1f3e2e
Autor:
Maddalena Di Sanzo, Ilenia Aversa, Gianluca Santamaria, Monica Gagliardi, Mariafranca Panebianco, Flavia Biamonte, Fabiana Zolea, Maria Concetta Faniello, Giovanni Cuda, Francesco Costanzo
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151359 (2016)
Ferritin, the major iron storage protein, performs its essential functions in the cytoplasm, nucleus and mitochondria. The variable assembly of 24 subunits of the Heavy (H) and Light (L) type composes the cytoplasmic molecule. In humans, two distinct
Externí odkaz:
https://doaj.org/article/6ea0451e64f64d11a25e1d001c194825
Autor:
Ilenia Aversa, Roberta Chirillo, Emanuela Chiarella, Fabiana Zolea, Maddalena Di Sanzo, Flavia Biamonte, Camillo Palmieri, Francesco Costanzo
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2969 (2018)
Nuclear Factor-κB (NF-κB) is frequently activated in tumor cells contributing to aggressive tumor growth and resistance to chemotherapy. Here we demonstrate that Ferritin Heavy Chain (FHC) protein expression inversely correlates with NF-κB activat
Externí odkaz:
https://doaj.org/article/0796d88384c44a63aca63fdcc6aa64a9
Autor:
Flavia Biamonte, Fabiana Zolea, Andrea Bisognin, Maddalena Di Sanzo, Claudia Saccoman, Domenica Scumaci, Ilenia Aversa, Mariafranca Panebianco, Maria Concetta Faniello, Stefania Bortoluzzi, Giovanni Cuda, Francesco Costanzo
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122105 (2015)
In a previous study, we showed that the silencing of the heavy subunit (FHC) offerritin, the central iron storage molecule in the cell, is accompanied by a modification in global gene expression. In this work, we explored whether different FHC amount
Externí odkaz:
https://doaj.org/article/42aab5d16d29438599c38cd9aa03613e
Autor:
Cristina Quintavalle, Arianna Pastore, Lorenzo Manna, Maddalena Di Sanzo, Alessia Polverino, Maria Concetta Faniello, Michela Grosso, Paola Costanzo, Giuseppina Divisato, Elena Cesaro
Publikováno v:
Human molecular genetics. 30(22)
Background: The zinc finger protein ZNF224 plays a dual role in human cancers, operating as both tumour suppressor and oncogenic factor depending on the cellular context and molecular partners. In this research, we investigated the role played by ZNF
Autor:
Flavia Biamonte, Barbara Quaresima, Maria Concetta Faniello, Camillo Palmieri, Maddalena Di Sanzo
Publikováno v:
Cells, Vol 9, Iss 2554, p 2554 (2020)
Cells
Cells
Ferritin, the principal intracellular iron-storage protein localized in the cytoplasm, nucleus, and mitochondria, plays a major role in iron metabolism. The encoding ferritin genes are members of a multigene family that includes some pseudogenes. Eve
Autor:
Fabiana Zolea, Anna Di Vito, Francesco Costanzo, Giovanni Cuda, Francesca Trecroci, Anna Cozzi, Nadia Lobello, Flavia Biamonte, Enzo Di Fabrizio, Maddalena Di Sanzo, Barbara Quaresima, Sonia Levi, Patrizio Candeloro
Publikováno v:
Free Radical Biology and Medicine. 89:614-623
The redox state of the cell is involved in the regulation of many physiological functions as well as in the pathogenesis of several diseases, and is strictly dependent on the amount of iron in its catalytically active state. Alterations of iron homeo