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pro vyhledávání: '"Maddalena Ceccon"'
Autor:
Maura Floreani, Laura Facci, Maddalena Ceccon, Marta Imbesi, Pietro Giusti, Stephen D. Skaper, Gianfranco Borin
Publikováno v:
Brain Research. 862:83-89
Glutathione (GSH) is a key component of the cellular defence cascade against injury caused by reactive oxygen species. Kainic acid (KA) is a potent central nervous system excitotoxin. KA-elicited neuronal death may result from the generation of ROS.
Publikováno v:
Neuropharmacology. 40(4)
Using rapid agonist applications to transfected HEK-293 cells, we investigated pregnenolone sulfate (PS) effects on deactivation and desensitization of recombinant NMDA receptors subtypes. PS prolonged the deactivation of responses produced by brief