Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Madan Katragadda"'
Autor:
Jeffrey Schlom, Jacques Moisan, Claudia Palena, Kristen Fousek, Lucas A Horn, Andrew Bayliffe, Haiyan Qin, Shantel Angstadt, Madan Katragadda
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/72661056b7144beaa9869fc142c17519
Autor:
Adam R. Root, Gurkan Guntas, Madan Katragadda, James R. Apgar, Jatin Narula, Chew Shun Chang, Sara Hanscom, Matthew McKenna, Jason Wade, Caryl Meade, Weijun Ma, Yongjing Guo, Yan Liu, Weili Duan, Claire Hendershot, Amy C. King, Yan Zhang, Eric Sousa, Amy Tam, Susan Benard, Han Yang, Kerry Kelleher, Fang Jin, Nicole Piche-Nicholas, Sinead E. Keating, Fernando Narciandi, Rosemary Lawrence-Henderson, Maya Arai, Wayne R. Stochaj, Kristine Svenson, Lidia Mosyak, Khetemcnee Lam, Christopher Francis, Kimberly Marquette, Liliana Wroblewska, H. Lily Zhu, Alfredo Darmanin Sheehan, Edward R. LaVallie, Aaron M. D’Antona, Alison Betts, Lindsay King, Edward Rosfjord, Orla Cunningham, Laura Lin, Puja Sapra, Lioudmila Tchistiakova, Divya Mathur, Laird Bloom
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
We report here the discovery and optimization of a novel T cell retargeting anti-GUCY2C x anti-CD3ε bispecific antibody for the treatment of solid tumors. Using a combination of hybridoma, phage display and rational design protein engineering, we ha
Externí odkaz:
https://doaj.org/article/25a52ae4f12b462d933f760c7786789d
Autor:
Puja Sapra, Christopher J. O'Donnell, Frank Loganzo, Lioudmila Tchistiakova, Hans-Peter Gerber, Edward Rosfjord, Andreas Giannakou, Xingzhi Tan, L. Nathan Tumey, Tracey Clark, Manoj B. Charati, Nadira Prashad, Russell Dushin, Andreas Maderna, Madan Katragadda, Mauricio Leal, Fan Jiang, Stephane Thibault, Wenyue Hu, Nicole Piché-Nicholas, Jennifer Kahler, Yoon-Chi Han
Purpose:Mortality due to acute myeloid leukemia (AML) remains high, and the management of relapsed or refractory AML continues to be therapeutically challenging. The reapproval of Mylotarg, an anti-CD33–calicheamicin antibody–drug conjugate (ADC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e6151cbf5978586286de379aa6d507
https://doi.org/10.1158/1078-0432.c.6530030
https://doi.org/10.1158/1078-0432.c.6530030
Autor:
Khiyam Hussain, Pierre Vantourout, Maria Poole, Josephine Eum Eum, Thomas Hayday, Adam Laing, Seb Battaglia, Madan Katragadda, Jessica Lowry, Jonathan Hsu, Adrian Hayday
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::700dbc137e318674c596ac9d5e92c7ff
https://doi.org/10.1136/jitc-2022-sitc2022.1392
https://doi.org/10.1136/jitc-2022-sitc2022.1392
Autor:
Orla Cunningham, Eric Sousa, Susan Benard, Yongjing Guo, C.M. Francis, Puja Sapra, Laura Lin, Lindsay King, Fang Jin, Weijun Ma, Aaron M. D’Antona, Nicole Piche-Nicholas, Sinead E. Keating, Sara Hanscom, Gurkan Guntas, Wayne Stochaj, Khetemcnee Lam, Claire Hendershot, Liliana Wroblewska, H. Lily Zhu, Kimberly Ann Marquette, Kristine Svenson, Divya Mathur, Fernando Narciandi, Yan Liu, Weili Duan, Edward R. Lavallie, Alison Betts, Rosemary Lawrence-Henderson, Chang Chew Shun, Adam Root, Maya Arai, Madan Katragadda, Amy King, Amy Tam, Jatin Narula, Jason Wade, Kerry Kelleher, Lioudmila Tchistiakova, Lidia Mosyak, Alfredo Darmanin Sheehan, Han Yang, Yan Zhang, James R. Apgar, Edward Rosfjord, Laird Bloom, Caryl L. Meade, Matthew McKenna
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
We report here the discovery and optimization of a novel T cell retargeting anti-GUCY2C x anti-CD3ε bispecific antibody for the treatment of solid tumors. Using a combination of hybridoma, phage display and rational design protein engineering, we ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c6dd5658cfd24d66b5b31b6d32bf8c
https://pubmed.ncbi.nlm.nih.gov/33459147
https://pubmed.ncbi.nlm.nih.gov/33459147
Autor:
Hans-Peter Gerber, L. Nathan Tumey, Fan Jiang, Stephane Thibault, Russell Dushin, Mauricio Leal, Frank Loganzo, Puja Sapra, Jennifer Kahler, Andreas Giannakou, Xingzhi Tan, Wenyue Hu, Manoj Charati, Nadira Anarkali Prashad, Yoon-Chi Han, Madan Katragadda, Andreas Maderna, Nicole Piche-Nicholas, Tracey Clark, Lioudmila Tchistiakova, Christopher J. O’Donnell, Edward Rosfjord
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(2)
Purpose: Mortality due to acute myeloid leukemia (AML) remains high, and the management of relapsed or refractory AML continues to be therapeutically challenging. The reapproval of Mylotarg, an anti-CD33–calicheamicin antibody–drug conjugate (ADC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14f68a9e1e89b01608589344919991c
https://pubmed.ncbi.nlm.nih.gov/33148666
https://pubmed.ncbi.nlm.nih.gov/33148666
Autor:
Denise O'Hara, Madan Katragadda, Amy King, Mania Kavosi, Lindsay B. Avery, Lioudmila Tchistiakova, Mengmeng Wang, Nicole Piche-Nicholas
Publikováno v:
mAbs
A large body of data exists demonstrating that neonatal Fc receptor (FcRn) binding of an IgG via its Fc CH2-CH3 interface trends with the pharmacokinetics (PK) of IgG. We have observed that PK of IgG molecules vary widely, even when they share identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d7f273db644d92d70b3d058742fc4f
https://doi.org/10.1080/19420862.2017.1389355
https://doi.org/10.1080/19420862.2017.1389355
Autor:
Madan Katragadda, Yijie Gao
Publikováno v:
Optimizing Antibody-Drug Conjugates for Targeted Delivery of Therapeutics. :168-184
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::080c0a7507cf7ba4ecfce139cfd3de33
https://doi.org/10.4155/fseb2013.14.116
https://doi.org/10.4155/fseb2013.14.116
Autor:
Oona Delpuech-Adams, Timothy P Hickling, Michael Westby, John Marcek, Nigel Horscroft, Sasha Sreckovic, Michael T. Lawton, Jaiessh Rawal, Madan Katragadda, M Victoria Flores, Boris Savic, Mark Fidock, Giuseppe Ciaramella, Linda F. Nelms, Nicola Melanie Robas, Makeida Stubbs, Thomas Corey
Publikováno v:
Antiviral Therapy. 17:869-881
Background This study presents preclinical data of a novel interferon (IFN)-α8 fusion protein, PF-04849285, and compares it with IFN-α2 and pegylated IFN-α2; the latter being the current standard of care for HCV. Methods The antiviral properties w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b594a979ddbf39cde8756746153af2a
https://doi.org/10.3851/imp2106
https://doi.org/10.3851/imp2106
Autor:
Mark A. Moffat, Kazuyuki Inagaki, Hideaki Shimada, Bernard N. Violand, Shinji Ogawa, Robert H. Arch, Jaime L. Masferrer, Aisuke Nii, Isami Fujita, Madan Katragadda, Takashi Ochi
Publikováno v:
Hepatology Research. 40:1128-1141
Aim: To evaluate the usefulness of a platelet-derived growth factor (PDGF)-B specific monoclonal antibody (mAb) as a therapeutic agent to treat chronic liver fibrosis. Methods: Liver fibrosis was induced in ICR mice by bile duct ligation (BDL) or BAL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31c92f867b193f315c7018f004c3bb46
https://doi.org/10.1111/j.1872-034x.2010.00718.x
https://doi.org/10.1111/j.1872-034x.2010.00718.x