Inhibition of the αvβ6integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis

Autor: Madala, SK, Korfhagen, TR, Schmidt, S, Davidson, C, Edukulla, R, Ikegami, M, Violette, SM, Weinreb, PH, Sheppard, D, Hardie, WD

Publikováno v: Madala, SK; Korfhagen, TR; Schmidt, S; Davidson, C; Edukulla, R; Ikegami, M; et al.(2014). Inhibition of the αvβ6integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis. American Journal of Physiology-Lung Cellular and Molecular Physiology, 306(8). doi: 10.1152/ajplung.00357.2013. UCSF: Retrieved from: http://www.escholarship.org/uc/item/72v7z0mw

A number of growth factors and signaling pathways regulate matrix deposition and fibroblast proliferation in the lung. The epidermal growth factor receptor (EGFR) family of receptors and the transforming growth factor-β (TGF-β) family are active in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::5714857db0baf5f8f29d8bf17b274d96
http://www.escholarship.org/uc/item/72v7z0mw

Interleukin 31 receptor α promotes smooth muscle cell contraction and airway hyperresponsiveness in asthma.

Autor: Akkenepally SV; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.; Division of Biochemistry, National Institute of Nutrition, Hyderabad, Telangana, India., Yombo DJK; Division of Pulmonary Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Yerubandi S; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.; Division of Pulmonary Medicine, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Reddy GB; Division of Biochemistry, National Institute of Nutrition, Hyderabad, Telangana, India., Deshpande DA; Division of Pulmonary, Allergy, and Critical Care Medicine, Center for Translational Medicine, Jane and Leonard Korman Respiratory Institute, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., McCormack FX; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA., Madala SK; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA. madalash@ucmail.uc.edu.

Publikováno v: Nature communications [Nat Commun] 2023 Dec 11; Vol. 14 (1), pp. 8207. Date of Electronic Publication: 2023 Dec 11.

Wnt signaling regulates ion channel expression to promote smooth muscle and cartilage formation in developing mouse trachea.

Autor: Russell NX; Neonatology and Pulmonary Biology Perinatal Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati Honors Program, Cincinnati, Ohio, United States., Burra K; Neonatology and Pulmonary Biology Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States., Shah RM; Neonatology and Pulmonary Biology Perinatal Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati Honors Program, Cincinnati, Ohio, United States., Bottasso-Arias N; Neonatology and Pulmonary Biology Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States., Mohanakrishnan M; Neonatology and Pulmonary Biology Perinatal Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati Honors Program, Cincinnati, Ohio, United States., Snowball J; Neonatology and Pulmonary Biology Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States., Ediga HH; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States., Madala SK; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States., Sinner D; Neonatology and Pulmonary Biology Perinatal Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati, College of Medicine, Cincinnati, Ohio, United States.

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2023 Dec 01; Vol. 325 (6), pp. L788-L802. Date of Electronic Publication: 2023 Oct 24.

Searching for an Animal Model with Clinical Features of Scleroderma.

Autor: Vliagoftis H; Division of Pulmonary Medicine and Alberta Respiratory Centre University of Alberta Edmonton, Alberta, Canada., Madala SK; Department of Internal Medicine University of Cincinnati Cincinnati, Ohio.

Publikováno v: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2023 Oct; Vol. 69 (4), pp. 373-375.

Wilms Tumor 1-Driven Fibroblast Activation and Subpleural Thickening in Idiopathic Pulmonary Fibrosis.

Autor: Gajjala PR; Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati, Cincinnati, OH 45267-0564, USA., Singh P; Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati, Cincinnati, OH 45267-0564, USA., Odayar V; Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati, Cincinnati, OH 45267-0564, USA., Ediga HH; Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati, Cincinnati, OH 45267-0564, USA., McCormack FX; Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati, Cincinnati, OH 45267-0564, USA., Madala SK; Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati, Cincinnati, OH 45267-0564, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 02; Vol. 24 (3). Date of Electronic Publication: 2023 Feb 02.