Výsledky vyhledávání - "Macular degeneration/drug therapy"

A 5-year longitudinal study of macular atrophy

Autor: Pinheiro, Rosa Lomelino, Farinha, Cláudia, Cachulo, Maria da Luz, Soares, Mário, Melo, Pedro, Murta, Joaquim, Silva, Rufino

Publikováno v: Revista Sociedade Portuguesa de Oftalmologia; Vol. 46 No. 1 (2022); 7-14
Revista Sociedade Portuguesa de Oftalmologia; Vol. 46 N.º 1 (2022); 7-14

Macular atrophy (MA) is one of the late stages of age-related macular degeneration (AMD) and leads to irreversible loss of visual function. During the past years, efforts have been made towards a more detailed comprehension of the characteristics of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=sarcservicod::e88a6f7f14f1b13891073565912782db
https://revistas.rcaap.pt/oftalmologia/article/view/25965

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Automated Quantification of Pathological Fluids in Neovascular Age-Related Macular Degeneration, and Its Repeatability Using Deep Learning

Autor: Agata Mosinska, Jacopo Guidotti, Stefanos Apostolopoulos, Sandro De Zanet, Irmela Mantel, Ciara Bergin, Carlos Ciller, Maria Sole Polito

Publikováno v: Translational Vision Science & Technology
Translational vision science & technology, vol. 10, no. 4, pp. 17

Purpose To develop a reliable algorithm for the automated identification, localization, and volume measurement of exudative manifestations in neovascular age-related macular degeneration (nAMD), including intraretinal (IRF), subretinal fluid (SRF), a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34709db288b1a146ea4552747e078fd2
http://europepmc.org/articles/PMC8083067

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Defining Nonadherence and Nonpersistence to Anti–Vascular Endothelial Growth Factor Therapies in Neovascular Age-Related Macular Degeneration

Autor: Vincent Daien, Paul Mitchell, Mali Okada, Anat Loewenstein, Robert Finger, Francisco Rodríguez, S. James Talks, Tien Yin Wong, Jane Barratt, Bora Eldem, Richard Gale, Tariq Aslam

Publikováno v: JAMA Ophthalmol
Okada, M, Wong, T Y, Mitchell, P, Eldem, B, Talks, S J, Aslam, T, Daien, V, Rodriguez, F J, Gale, R, Barratt, J, Finger, R P & Loewenstein, A 2021, ' Defining Nonadherence and Nonpersistence to Anti-Vascular Endothelial Growth Factor Therapies in Neovascular Age-Related Macular Degeneration ', JAMA Ophthalmology, vol. 139, no. 7, pp. 769-776 . https://doi.org/10.1001/jamaophthalmol.2021.1660

Importance: Poor adherence or persistence to treatment can be a barrier to optimizing clinical practice (real-world) outcomes to intravitreal injection therapy in patients with neovascular age-related macular degeneration (nAMD). Currently, there is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee74b34e222df52d76c086835b8b2fd9
https://doi.org/10.1001/jamaophthalmol.2021.1660

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MACULAR ATROPHY INCIDENCE IN ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR-TREATED NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: Risk Factor Evaluation for Individualized Treatment Need of Ranibizumab or Aflibercept According to an Observe-and-Plan Regimen

Autor: Ciara Bergin, Irmela Mantel, Parmis Parvin, Sophie de Massougnes, Marta Zola, Ali Dirani

Publikováno v: Retina, vol. 39, no. 5, pp. 906-917

To investigate factors associated with macular atrophy (MA) incidence in neovascular age-related macular degeneration treated with either ranibizumab or aflibercept in an Observe-and-Plan variable dosing regimen. Information was obtained from two ide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82ce6d7f1abe3bf1d6256ea32c6e37e
https://serval.unil.ch/resource/serval:BIB_160E4E5271F0.P001/REF.pdf

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Strategies for modifying drug residence time and ocular bioavailability to decrease treatment frequency for back of the eye diseases

Autor: Yogeshvar N. Kalia, Robert F. Kelley, Stefan T. Yohe, Jeffrey Aaronson, Whitney Shatz

Publikováno v: Expert Opinion on Drug Delivery, Vol. 16, No 1 (2019) pp. 43-57

Treating posterior eye diseases has become a major area of focus for pharmaceutical and biotechnology companies. Current standard of care for treating posterior eye diseases relies on administration via intravitreal injection. Although effective, thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66aa43841bdbf39d1522025b18e2a392
https://archive-ouverte.unige.ch/unige:138474

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Mineralocorticoid receptor antagonism limits experimental choroidal neovascularization and structural changes associated with neovascular age-related macular degeneration

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.369. ⟨10.1038/s41467-018-08125-6⟩
Nature communications, vol. 10, no. 1, pp. 369
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

Choroidal neovascularization (CNV) is a major cause of visual impairment in patients suffering from wet age-related macular degeneration (AMD), particularly when refractory to intraocular anti-VEGF injections. Here we report that treatment with the o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::228cace5caba338259e157d974dc8c97
https://hal.sorbonne-universite.fr/hal-01997678

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Antidepressant medication and ocular factors in association with the need for anti-VEGF retreatment in neovascular age-related macular degeneration

Autor: Raphaël Gaillard, Olivier Mir, Irmela Mantel, Francine Behar-Cohen, Marta Zola

Publikováno v: British Journal of Ophthalmology
British Journal of Ophthalmology, BMJ Publishing Group, 2019, 103 (6), pp.811-815. ⟨10.1136/bjophthalmol-2018-312318⟩
The British journal of ophthalmology, vol. 103, no. 6, pp. 811-815
The British Journal of Ophthalmology
British Journal of Ophthalmology, 2019, 103 (6), pp.811-815. ⟨10.1136/bjophthalmol-2018-312318⟩

Background/AimsVascular endothelial growth factor (VEGF) is a key player in the pathogenesis of neovascular age-related macular degeneration (nAMD) and is also involved in the final common pathway of antidepressant medication. This study investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9c0a17603af25ab3132104da96598c
https://hal.sorbonne-universite.fr/hal-02172259/document

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