A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling

Autor: Bernard Thienpont, Valentina Pomella, Hanne Vos, Siel Olbrecht, Marlies Vanden Bempt, Birgit Weynand, Diether Lambrechts, Sara Verbandt, Junbin Qian, Yannick Van Herck, Els Wauters, Ann Smeets, A. Franken, Asier Antoranz, Jieyi Xiong, Ayse Bassez, Sabine Tejpar, Emre Etlioglu, Giuseppe Floris, Francesca Maria Bosisio, Bram Boeckx, Pieter Busschaert, Damya Laoui, Ignace Vergote

Publikováno v: Cell Research

The stromal compartment of the tumor microenvironment consists of a heterogeneous set of tissue-resident and tumor-infiltrating cells, which are profoundly moulded by cancer cells. An outstanding question is to what extent this heterogeneity is simil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f25bf042b9e65a5256b1f18b046ca0
https://biblio.vub.ac.be/vubir/a-pancancer-blueprint-of-the-heterogeneous-tumor-microenvironment-revealed-by-singlecell-profiling(b9f0fba4-7320-4a10-8710-c4f14ad1b675).html

Zika Virus Targets Multiple Tissues and Cell Types During the First Trimester of Pregnancy

Autor: Francisco Veas, Nabila Jabrane-Ferrat

Publikováno v: Zika Virus
Zika Virus, 2142, Springer US, pp.235-249, 2020, Methods in Molecular Biology, ⟨10.1007/978-1-0716-0581-3_18⟩
Zika Virus : Methods and protocols
Kobinger G.; Racine T. Zika Virus : Methods and protocols, 2142, Humana, pp.235-249, 2020, Methods in Molecular Biology, 978-1-0716-0580-6. ⟨10.1007/978-1-0716-0581-3_18⟩
Methods in Molecular Biology ISBN: 9781071605806

International audience; The 2016 Zika virus (ZIKV) outbreak in the Americas has been characterized by an increased association frequency of fetal neuropathological abnormalities. To have a comprehensive and accurate knowledge of key elements of the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834256b3a184288f7d10bbe85b24bc05
https://hal-cnrs.archives-ouvertes.fr/hal-03411920

The evaluation of the distribution of CD133, CXCR1 and the tumor associated macrophages in different molecular subtypes of breast cancer

Autor: Ilgın, Can, Çomut, Erdem, Sarıgül, Çağlar, Korkmaz, Selçuk, Vardar, Enver, Müftüoğlu, Sevda Fatma

Publikováno v: DIGITUM. Depósito Digital Institucional de la Universidad de Murcia
Universitat Politècnica de Catalunya (UPC)

Breast cancer has different molecular subtypes, which determine the prognosis and response to the treatment. CD133 is a marker for cancer stem cells in tumor microenvironment with diagnostic/therapeutic importance. The tumor associated macrophages (T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::82c704ac241c5bdd7f07c23211cdf150
http://hdl.handle.net/10201/125026

Re-education of macrophages as a therapeutic strategy in cancer

Autor: Kowal, J., Kornete, M., Joyce, J.A.

Publikováno v: Immunotherapy, vol. 11, no. 8, pp. 677-689

Tumor-associated macrophages (TAMs) can be educated within the tumor microenvironment to promote cancer development and progression. While TAM-targeted agents have largely focused on macrophage depletion as an anticancer strategy, it is becoming incr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1900::6530c3446f0c8d3bfd5287b129874e86
https://serval.unil.ch/notice/serval:BIB_7E2B9DDA760A

A proliferation‐inducing ligand–mediated anti‐inflammatory response of astrocytes in multiple sclerosis

Autor: Mahdia Benkhoucha, Mashal Claude Ahmed, Dominique Baeten, Romain Marignier, Jose Boucraut, Olivier Casez, Michael Hahne, Jean Boutonnat, Corinne Sonrier, Benoit Manfroi, Laurie Baert, Patrice N. Marche, Nathalie Sturm, Marine Tessier, Patrice H. Lalive, Romain R. Vivès, Bertrand Huard, Cyril Rivat, Catherine Ghezzi, Hans Lassmann, Pascal Schneider, Natalia Popa, Gilda Raguenez, Alexis Broisat, Hugues Lortat-Jacob, Mitra Ahmadi

Publikováno v: Annals of Neurology
Annals of Neurology, Wiley, 2019, 85 (3), pp.406-420. ⟨10.1002/ana.25415⟩
Annals of neurology, vol. 85, no. 3, pp. 406-420
Annals of neurology, 85(3), 406-420. John Wiley and Sons Inc.
Annals of Neurology, 2019, 85 (3), pp.406-420. ⟨10.1002/ana.25415⟩

International audience; OBJECTIVE:The two related tumor necrosis factor members a proliferation-inducing ligand (APRIL) and B-cell activation factor (BAFF) are currently targeted in autoimmune diseases as B-cell regulators. In multiple sclerosis (MS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64212102082e58fcca9193ce04f096a3
https://www.hal.inserm.fr/inserm-02332844