Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Macrophages/*immunology"'
Publikováno v:
Clin Exp Immunol
Krei, J M, Møller, H J & Larsen, J B 2021, ' The role of interleukin-18 in the diagnosis and monitoring of hemophagocytic lymphohistiocytosis/macrophage activation syndrome – a systematic review ', Clinical and Experimental Immunology, vol. 203, no. 2, pp. 174-182 . https://doi.org/10.1111/cei.13543
Krei, J M, Møller, H J & Larsen, J B 2021, ' The role of interleukin-18 in the diagnosis and monitoring of hemophagocytic lymphohistiocytosis/macrophage activation syndrome – a systematic review ', Clinical and Experimental Immunology, vol. 203, no. 2, pp. 174-182 . https://doi.org/10.1111/cei.13543
Summary Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, hyperinflammatory disorder, characterized by multiorgan failure, fever and cytopenias. The diagnosis of HLH and its subtype Macrophage Activation Syndrome (MAS) remains a challen
Autor:
Anne-Laure Rougemont, Vladimir L. Cousin, Laura Rubbia-Brandt, Jean Villard, Valérie A. McLin, Sylvie Ferrari-Lacraz, Barbara E. Wildhaber
Publikováno v:
Transplantation, Vol. 104, No 8 (2020) pp. 1633-1643
Background The cellular infiltrate in protocol liver biopsies (PB) following pediatric liver transplantation remains mostly uncharacterized, yet there is increasing concern about the role of inflammation and fibrosis in long-term liver allografts. We
Autor:
Teresa Carvalho, Albel Singh, Jeremy Sousa, Luisa Simoes-Costa, Álvaro Chiner-Oms, Leandro Barros, Nuno S. Osório, Apoorva Bhatt, Cristina P. Vieira, Baltazar Cá, Maria Isabel Veiga, António G. Castro, Ana Raquel Maceiras, Sebastien Gagneux, Ana Isabel Rodrigues Fernandes, João Tiago Guimarães, António Amorim, Iñaki Comas, Helder Novais Bastos, Kaori L. Fonseca, Pedro Rodrigues, Carlos Magalhães, Margarida Saraiva, Rui Pereira, Angélica Ramos, Jorge Vieira, Fernando Rodrigues, Henrique Machado
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
14 páginas, 6 figuras. Supplementary information is available for this paper at https://doi.org/10.1038/s41467-020-15832-6. Sequence data are deposited on NCBI GEO database with the accession code GSE138580
Genetic diversity of Mycobacterium tu
Genetic diversity of Mycobacterium tu
Autor:
Alba Llibre, Martin Dedicoat, Julie G. Burel, Caroline Demangel, Matthew K. O’Shea, Claudio Mauro
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 2021, 12, pp.747387. ⟨10.3389/fimmu.2021.747387⟩
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, 2021, 12, pp.747387. ⟨10.3389/fimmu.2021.747387⟩
Frontiers in Immunology, Vol 12 (2021)
Mycobacterial diseases are a major public health challenge. Their causative agents include, in order of impact, members of theMycobacterium tuberculosiscomplex (causing tuberculosis),Mycobacterium leprae(causing leprosy), and non-tuberculous mycobact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c8bd617d292a80678dcec0985a1d59
https://hal-pasteur.archives-ouvertes.fr/pasteur-03903851/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03903851/document
Autor:
Werner Müller, Hannah Smith, Louis Boon, Kelly Wemyss, Iris Mair, Judith E. Allen, Larisa Logunova, Ruth Forman, Kathryn J. Else, Joanne L. Pennock
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009768 (2021)
Forman, R, Logunova, L, Smith, H, Wemyss, K, Mair, I, Boon, L, Allen, J, Muller, W, Pennock, J & Else, K 2021, ' Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELM alpha plus macrophages ', PL o S Pathogens, vol. 17, no. 7, e1009768, pp. e1009768 . https://doi.org/10.1371/journal.ppat.1009768
PLoS Pathogens
Forman, R, Logunova, L, Smith, H, Wemyss, K, Mair, I, Boon, L, Allen, J, Muller, W, Pennock, J & Else, K 2021, ' Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELM alpha plus macrophages ', PL o S Pathogens, vol. 17, no. 7, e1009768, pp. e1009768 . https://doi.org/10.1371/journal.ppat.1009768
PLoS Pathogens
The intestinal nematode parasite Trichuris muris dwells in the caecum and proximal colon driving an acute resolving intestinal inflammation dominated by the presence of macrophages. Notably, these macrophages are characterised by their expression of
Autor:
Tom O'Toole, Yvette van Kooyk, Katarzyna Olesek, Joke M. M. den Haan, Floris J. Bikker, Eline S. Zwart, Geert Kazemier, Alsya J. Affandi, Helen J Pijffers, Joanna Grabowska, Ernesto Rodríguez, Tanja D. de Gruijl, Martino Ambrosini, Johannes Stöckl, Patrick P G Mulder, Kamran Nazmi, Gert Storm, Hakan Kalay, Miguel Lopez Venegas, Arnaud Barbaria, Alfons J.M. van den Eertwegh
Publikováno v:
Affandi, A J, Grabowska, J, Olesek, K, Venegas, M L, Barbaria, A, Rodríguez, E, Mulder, P P G, Pijffers, H J, Ambrosini, M, Kalay, H, O’Toole, T, Zwart, E S, Kazemier, G, Nazmi, K, Bikker, F J, Stöckl, J, van den Eertwegh, A J M, de Gruijl, T D, Storm, G, van Kooyk, Y & den Haan, J M M 2020, ' Selective tumor antigen vaccine delivery to human CD169 + antigen-presenting cells using ganglioside-liposomes ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 44, pp. 27528-27539 . https://doi.org/10.1073/pnas.2006186117
Proceedings of the National Academy of Sciences of the United States of America
Affandi, A J, Grabowska, J, Olesek, K, Lopez Venegas, M, Barbaria, A, Rodríguez, E, Mulder, P P G, Pijffers, H J, Ambrosini, M, Kalay, H, O'Toole, T, Zwart, E S, Kazemier, G, Nazmi, K, Bikker, F J, Stöckl, J, van den Eertwegh, A J M, de Gruijl, T D, Storm, G, van Kooyk, Y & den Haan, J M M 2020, ' Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 44, pp. 27528-27539 . https://doi.org/10.1073/pnas.2006186117
Proceedings of the National Academy of Sciences of the United States of America, 117(44), 27528-27539. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(44), 27528-27539. National Acad Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(44), 27528. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Affandi, A J, Grabowska, J, Olesek, K, Lopez Venegas, M, Barbaria, A, Rodríguez, E, Mulder, P P G, Pijffers, H J, Ambrosini, M, Kalay, H, O'Toole, T, Zwart, E S, Kazemier, G, Nazmi, K, Bikker, F J, Stöckl, J, van den Eertwegh, A J M, de Gruijl, T D, Storm, G, van Kooyk, Y & den Haan, J M M 2020, ' Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 44, pp. 27528-27539 . https://doi.org/10.1073/pnas.2006186117
Proceedings of the National Academy of Sciences of the United States of America, 117(44), 27528-27539. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(44), 27528-27539. National Acad Sciences
Proceedings of the National Academy of Sciences of the United States of America, 117(44), 27528. National Academy of Sciences
Significance Current immunotherapies only benefit a minority of all cancer patients, so it is necessary to develop other strategies to boost patients’ antitumor CD8+ T cell responses. Here, we formulated a liposomal vaccine carrier that selectively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5b0bd2f3d5b21a1135dc801af5210a
https://hdl.handle.net/1871.1/cd09ac07-dd23-4fd5-bd76-87f3083ea0b311245.1/3914c7d1-8c17-47bd-aaff-f6dbcfb36ea3
https://hdl.handle.net/1871.1/cd09ac07-dd23-4fd5-bd76-87f3083ea0b311245.1/3914c7d1-8c17-47bd-aaff-f6dbcfb36ea3
Autor:
Deirdre Cronin-Fenton, Ivar Skaland, Miriam Ragle Aure, Kristine Kleivi Sahlberg, Kristin Jonsdottir, Nina Egeland, Einar Gudlaugsson, Emiel A. M. Janssen, Jan P. A. Baak, Vessela N. Kristensen
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Egeland, N G, Jonsdottir, K, Aure, M R, Sahlberg, K, Kristensen, V N, Cronin-Fenton, D, Skaland, I, Gudlaugsson, E, Baak, J P A & Janssen, E A M 2020, ' MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers ', BMC Cancer, vol. 20, no. 1, pp. 377 . https://doi.org/10.1186/s12885-020-06857-7
377 (2020)
Egeland, N G, Jonsdottir, K, Aure, M R, Sahlberg, K, Kristensen, V N, Cronin-Fenton, D, Skaland, I, Gudlaugsson, E, Baak, J P A & Janssen, E A M 2020, ' MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers ', BMC Cancer, vol. 20, no. 1, 377 . https://doi.org/10.1186/s12885-020-06857-7
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Egeland, N G, Jonsdottir, K, Aure, M R, Sahlberg, K, Kristensen, V N, Cronin-Fenton, D, Skaland, I, Gudlaugsson, E, Baak, J P A & Janssen, E A M 2020, ' MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers ', BMC Cancer, vol. 20, no. 1, pp. 377 . https://doi.org/10.1186/s12885-020-06857-7
377 (2020)
Egeland, N G, Jonsdottir, K, Aure, M R, Sahlberg, K, Kristensen, V N, Cronin-Fenton, D, Skaland, I, Gudlaugsson, E, Baak, J P A & Janssen, E A M 2020, ' MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers ', BMC Cancer, vol. 20, no. 1, 377 . https://doi.org/10.1186/s12885-020-06857-7
Background Previously, we have shown that miR-18a and miR-18b gene expression strongly correlates with high proliferation, oestrogen receptor -negativity (ER−), cytokeratin 5/6 positivity and basal-like features of breast cancer. Methods We investi
Autor:
Jo A. Van Ginderachter, Slavko Mojsilović, Yu Si, Gosse J. Adema, Sven Brandau, Jadwiga Jablonska, Juan F. Santibanez, Jarosław Baran, Maria Velegraki, Isabela Sieminska, Xiaoying Hu, Karine Serre, Helen A. Papadaki, Yago Pico de Coaña, Viktor Umansky, Kim C. M. Santegoets, Zvi G. Fridlender
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cancer Immunology Immunotherapy, 68, 645-660
Cancer Immunology Immunotherapy
Cancer Immunology Immunotherapy, 68, 4, pp. 645-660
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cancer Immunology Immunotherapy, 68, 645-660
Cancer Immunology Immunotherapy
Cancer Immunology Immunotherapy, 68, 4, pp. 645-660
© Springer-Verlag GmbH Germany, part of Springer Nature 2018
Mounting evidence has accumulated on the critical role of the different myeloid cells in the regulation of the cancerous process, and in particular in the modulation of the immune rea
Mounting evidence has accumulated on the critical role of the different myeloid cells in the regulation of the cancerous process, and in particular in the modulation of the immune rea
Publikováno v:
Cell Reports, Vol 19, Iss 1, Pp 101-113 (2017)
Cell reports
Cell reports, vol. 19, no. 1, pp. 101-113
Cell reports
Cell reports, vol. 19, no. 1, pp. 101-113
SUMMARY Antimitotic agents, including Taxol, disrupt microtubule dynamics and cause a protracted mitotic arrest and subsequent cell death. Despite the broad utility of these drugs in breast cancer and other tumor types, clinical response remains vari
Autor:
Géraldine Bart, Benoit Le Goff, Pierre Layrolle, Cem Gabay, Frédéric Blanchard, Gaby Palmer, Aurélie Najm, Régis Brion, S Touchais, Valérie Trichet, Marie-Astrid Boutet
Publikováno v:
Annals of the Rheumatic Diseases, Vol. 76, No 7 (2017) pp. 1304-1312
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2017, 76 (7), pp.1304-1312. ⟨10.1136/annrheumdis-2016-210630⟩
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2017, 76 (7), pp.1304-1312. ⟨10.1136/annrheumdis-2016-210630⟩
International audience; OBJECTIVES:Interleukin (IL)-38 is a newly characterised cytokine that belongs to the IL-1 family. This cytokine is expressed in the rheumatoid arthritis (RA) synovial tissue and IL-38 deficient mice have exacerbated arthritis.