Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Macrophage heterogeneity"'
Publikováno v:
Bioactive Materials, Vol 39, Iss , Pp 302-316 (2024)
Diabetic wounds, characterized by prolonged inflammation and impaired vascularization, are a serious complication of diabetes. This study aimed to design a gelatin methacrylate (GelMA) hydrogel for the sustained release of netrin-1 and evaluate its p
Externí odkaz:
https://doaj.org/article/0102443875474cc2916125767b24068c
Autor:
Han Jin, Woonghee Kim, Meng Yuan, Xiangyu Li, Hong Yang, Mengzhen Li, Mengnan Shi, Hasan Turkez, Mathias Uhlen, Cheng Zhang, Adil Mardinoglu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMacrophages and T cells play crucial roles in liver physiology, but their functional diversity in hepatocellular carcinoma (HCC) remains largely unknown.MethodsTwo bulk RNA-sequencing (RNA-seq) cohorts for HCC were analyzed using gene co-
Externí odkaz:
https://doaj.org/article/e8476c5fe8284c0a96763992a412a4af
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Macrophages and tumour stroma cells account for the main cellular components in the tumour microenvironment (TME). Current advancements in single-cell analysis have revolutionized our understanding of macrophage diversity and macrophage–st
Externí odkaz:
https://doaj.org/article/eed2b448d7a147eb99adfa1eeb11e5ed
Autor:
Ying Jiang, Wenpeng Yu, Tie Hu, Hanzhi Peng, Fajia Hu, Yong Yuan, Xufeng Liu, Songqing Lai, Jianliang Zhou, Xiao Dong
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Background and objectiveMacrophages play a crucial and dichotomous role cardiac repair following myocardial ischemia-reperfusion, as they can both facilitate tissue healing and contribute to injury. This duality is intricately linked to environmental
Externí odkaz:
https://doaj.org/article/8a033898a9c34348a161568c37736681
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/99af2635df3c489686b21a40c25464d6
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease harboring significant microenvironment heterogeneity, especially for the macrophages. Tumor-associated macrophages (TAMs) orchestrate PDAC malignancy, but their dy
Externí odkaz:
https://doaj.org/article/861b52cedf5c478095378f3142977bfc
Autor:
Yiying Zhang, Zhangyang Wang, Rongrong Wang, Lu Xia, Yiying Cai, Fangchao Tong, Yanqin Gao, Jing Ding, Xin Wang
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background Apoptosis signal-regulating kinase 1 (ASK1) not only causes neuronal programmed cell death via the mitochondrial pathway but also is an essential component of the signalling cascade during microglial activation. We hypothesize tha
Externí odkaz:
https://doaj.org/article/a27ba400298044e3a22a55ae286cb602
Autor:
Alex Yashchenko, Sarah J. Bland, Cheng J. Song, Ummey Khalecha Bintha Ahmed, Rachel Sharp, Isabella G. Darby, Audrey M. Cordova, Morgan E. Smith, Jeremie M. Lever, Zhang Li, Ernald J. Aloria, Shuja Khan, Bibi Maryam, Shanrun Liu, Michael R. Crowley, Kenneth L. Jones, Lauren A. Zenewicz, James F. George, Michal Mrug, David K. Crossman, Katharina Hopp, Stavros Stavrakis, Mary B. Humphrey, Florent Ginhoux, Kurt A. Zimmerman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Kidney macrophages are comprised of both monocyte-derived and tissue resident populations; however, the heterogeneity of kidney macrophages and factors that regulate their heterogeneity are poorly understood. Herein, we performed single cell RNA sequ
Externí odkaz:
https://doaj.org/article/33bd5d09e8bc4889bac131cdfd30c35a
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