Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Macrofilaricide"'
Autor:
Frederic Risch, Johanna F. Scheunemann, Julia J. Reichwald, Benjamin Lenz, Alexandra Ehrens, Joséphine Gal, Frédéric Fercoq, Marianne Koschel, Martina Fendler, Achim Hoerauf, Coralie Martin, Marc P. Hübner
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Filarial nematodes can cause debilitating diseases such as lymphatic filariasis and onchocerciasis. Oxfendazole (OXF) is one promising macrofilaricidal candidate with improved oral availability compared to flubendazole (FBZ), and OXF is currently und
Externí odkaz:
https://doaj.org/article/50e2c8efd04044ce9bfe78ec3cd8f293
Autor:
Hong, W. David, Benayoud, Farid, Nixon, Gemma L., Ford, Louise, Johnston, Kelly L., Clare, Rachel H., Cassidy, Andrew, Cook, Darren A. N., Siu, Amy, Shiotani, Motohiro, Webborn, Peter J. H., Kavanagh, Stefan, Aljayyoussi, Ghaith, Murphy, Emma, Steven, Andrew, Archer, John, Struever, Dominique, Frohberger, Stefan J., Ehrens, Alexandra, Hübner, Marc P., Hoerauf, Achim, Roberts, Adam P., Hubbard, Alasdair T. M., Tate, Edward W., Serwa, Remigiusz A., Leung, Suet C., Qie, Li, Berry, Neil G., Gusovsky, Fabian, Hemingway, Janet, Turner, Joseph D., Taylor, Mark J., Ward, Stephen A., O’Neill, Paul M.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 Jan . 116(4), 1414-1419.
Externí odkaz:
https://www.jstor.org/stable/26580255
Autor:
Walker, Martin, Pion, Sébastien D. S., Fang, Hanwei, Gardon, Jacques, Kamgno, Joseph, Basáñez, Maria-Gloria, Boussinesq, Michel
Publikováno v:
Clinical Infectious Diseases, 2017 Dec . 65(12), 2026-2034.
Externí odkaz:
https://www.jstor.org/stable/26524665
Autor:
Turner, Joseph D., Sharma, Raman, Al Jayoussi, Ghaith, Tyrer, Hayley E., Gamble, Joanne, Hayward, Laura, Priestley, Richard S., Murphy, Emma A., Davies, Jill, Waterhouse, David, Cook, Darren A. N., Clare, Rachel H., Cassidy, Andrew, Steven, Andrew, Johnston, Kelly L., McCall, John, Ford, Louise, Hemingway, Janet, Ward, Stephen A., Taylor, Mark J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Nov 01. 114(45), E9712-E9721.
Externí odkaz:
https://www.jstor.org/stable/26485753
Autor:
Maeghan O'Neill, Cristina Ballesteros, Lucienne Tritten, Erica Burkman, Weam I. Zaky, Jianguo Xia, Andrew Moorhead, Steven A. Williams, Timothy G. Geary
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 3, Pp 288-296 (2016)
The use of microfilaricidal drugs for the control of onchocerciasis and lymphatic filariasis (LF) necessitates prolonged yearly dosing. Prospects for elimination or eradication of these diseases would be enhanced by the availability of a macrofilaric
Externí odkaz:
https://doaj.org/article/5bcff3a8431c4cf1ac7beac8772806f4
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 5, Iss 3, Pp 135-140 (2015)
The use of a microfilaricidal drug for the control of onchocerciasis and lymphatic filariasis necessitates prolonged yearly dosing. Prospects for elimination or eradication of these diseases would be enhanced by availability of a macrofilaricidal dru
Externí odkaz:
https://doaj.org/article/9e065a672466429db361cf63c28593b2
Publikováno v:
Parasitology Research
Twenty diseases are recognized as neglected tropical diseases (NTDs) by World Health Assembly resolutions, including human filarial diseases. The end of NTDs is embedded within the Sustainable Development Goals for 2030, under target 3.3. Onchocercia
Autor:
Alice Halliday, Ana F Guimaraes, Hayley E Tyrer, Haelly Mejane Metuge, Chounna Ndongmo Winston Patrick, Kengne-Ouafo Jonas Arnaud, Tayong Dizzle Bita Kwenti, George Forsbrook, Andrew Steven, Darren Cook, Peter Enyong, Samuel Wanji, Mark J Taylor, Joseph D Turner
Publikováno v:
Parasites & Vectors, Vol 7, Iss 1, Pp 1-14 (2014)
Abstract Background New drugs effective against adult filariae (macrofilaricides) would accelerate the elimination of lymphatic filariasis and onchocerciasis. Anti-Onchocerca drug development is hampered by the lack of a facile model. We postulated t
Externí odkaz:
https://doaj.org/article/2c7f78145f3f4aae8129302a1eba8b3e
Akademický článek
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Autor:
Ann Verheyen, Emmie Dumont, Emmanuel Njumbe Ediage, Dirk Van Roosbroeck, Maurice R. Odiere, Lieven J. Stuyver, Ole Lagatie, Alexander Yaw Debrah, Filip Cuyckens, Lieve Dillen, Ruben T'Kindt, Tom Verhaeghe, Koen Sandra, Linda Batsa Debrah, Stijn Van Asten, Rob J. Vreeken
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009999 (2021)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
The neglected tropical disease onchocerciasis, or river blindness, is caused by infection with the filarial nematode Onchocerca volvulus. Current estimates indicate that 17 million people are infected worldwide, the majority of them living in Africa.