Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Maclean P. Nasrallah"'
Autor:
Jose L. Agraz, Carlos Agraz, Andrew A. Chen, Charles Rice, Robert S. Pozos, Sven Aelterman, Amanda Tan, Angela N. Viaene, MacLean P. Nasrallah, Parth Sharma, Caleb M. Grenko, Tahsin Kurc, Joel Saltz, Michael D. Feldman, Hamed Akbari, Russell T. Shinohara, Spyridon Bakas, Parker Wilson
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 6, Pp 35-40 (2025)
In the medical diagnostics domain, pathology and histology are pivotal for the precise identification of diseases. Digital histopathology, enhanced by automation, facilitates the efficient analysis of massive amount of biopsy images produced on a dai
Externí odkaz:
https://doaj.org/article/b030f1dc9ecb465a94aa6bee6081d1d8
Autor:
Jun Guo, Anahita Fathi Kazerooni, Erik Toorens, Hamed Akbari, Fanyang Yu, Chiharu Sako, Elizabeth Mamourian, Russell T. Shinohara, Constantinos Koumenis, Stephen J. Bagley, Jennifer J. D. Morrissette, Zev A. Binder, Steven Brem, Suyash Mohan, Robert A. Lustig, Donald M. O’Rourke, Tapan Ganguly, Spyridon Bakas, MacLean P. Nasrallah, Christos Davatzikos
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Glioblastoma is a highly heterogeneous disease, with variations observed at both phenotypical and molecular levels. Personalized therapies would be facilitated by non-invasive in vivo approaches for characterizing this heterogeneity. In this
Externí odkaz:
https://doaj.org/article/f5997dcf88784ed0a9eb262aa340f854
Autor:
Laiz Laura de Godoy, Suyash Mohan, Sumei Wang, MacLean P. Nasrallah, Yu Sakai, Donald M. O’Rourke, Stephen Bagley, Arati Desai, Laurie A. Loevner, Harish Poptani, Sanjeev Chawla
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Accurate differentiation of pseudoprogression (PsP) from tumor progression (TP) in glioblastomas (GBMs) is essential for appropriate clinical management and prognostication of these patients. In the present study, we sought to val
Externí odkaz:
https://doaj.org/article/939f563d0d71422b9916e708c2031dea
Autor:
Spyridon Bakas, Chiharu Sako, Hamed Akbari, Michel Bilello, Aristeidis Sotiras, Gaurav Shukla, Jeffrey D. Rudie, Natali Flores Santamaría, Anahita Fathi Kazerooni, Sarthak Pati, Saima Rathore, Elizabeth Mamourian, Sung Min Ha, William Parker, Jimit Doshi, Ujjwal Baid, Mark Bergman, Zev A. Binder, Ragini Verma, Robert A. Lustig, Arati S. Desai, Stephen J. Bagley, Zissimos Mourelatos, Jennifer Morrissette, Christopher D. Watt, Steven Brem, Ronald L. Wolf, Elias R. Melhem, MacLean P. Nasrallah, Suyash Mohan, Donald M. O’Rourke, Christos Davatzikos
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-12 (2022)
Measurement(s) Magnetic Resonance Imaging Technology Type(s) Magnetic Resonance Imaging of the Brain with and without Contrast Sample Characteristic - Organism Homo sapiens Sample Characteristic - Environment brain Sample Characteristic - Location Un
Externí odkaz:
https://doaj.org/article/5d5b415e3a86419991ae9fdec07415bc
Autor:
Rachael G. Aubin, Emma C. Troisi, Javier Montelongo, Adam N. Alghalith, Maclean P. Nasrallah, Mariarita Santi, Pablo G. Camara
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The molecular mechanisms underlying ependymoma tumorigenesis remain poorly understood. Here, single cell analysis of posterior fossa primary tumours and distal metastases highlights the role of pro-inflammatory cytokines in promoting epithelial-to-me
Externí odkaz:
https://doaj.org/article/5813a87138be474398527991ba01b4e8
Autor:
Anahita Fathi Kazerooni, Sanjay Saxena, Erik Toorens, Danni Tu, Vishnu Bashyam, Hamed Akbari, Elizabeth Mamourian, Chiharu Sako, Costas Koumenis, Ioannis Verginadis, Ragini Verma, Russell T. Shinohara, Arati S. Desai, Robert A. Lustig, Steven Brem, Suyash Mohan, Stephen J. Bagley, Tapan Ganguly, Donald M. O’Rourke, Spyridon Bakas, MacLean P. Nasrallah, Christos Davatzikos
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Multi-omic data, i.e., clinical measures, radiomic, and genetic data, capture multi-faceted tumor characteristics, contributing to a comprehensive patient risk assessment. Here, we investigate the additive value and independent reproducibili
Externí odkaz:
https://doaj.org/article/2e0a631fb2f84bd8ab1d9f8f31d56f26
Autor:
Matthew Torre, Varshini Vasudevaraja, Jonathan Serrano, Michael DeLorenzo, Seth Malinowski, Anne-Florence Blandin, Melanie Pages, Azra H. Ligon, Fei Dong, David M. Meredith, MacLean P. Nasrallah, Craig Horbinski, Sonika Dahiya, Keith L. Ligon, Mariarita Santi, Shakti H. Ramkissoon, Mariella G. Filbin, Matija Snuderl, Sanda Alexandrescu
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-14 (2020)
Abstract Fusions involving neurotrophic tyrosine receptor kinase (NTRK) genes are detected in ≤2% of gliomas and can promote gliomagenesis. The remarkable therapeutic efficacy of TRK inhibitors, which are among the first Food and Drug Administratio
Externí odkaz:
https://doaj.org/article/a13bf05804df41039d210cc899efdb56
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Pituicytoma is a rare, poorly characterized tumor of the sellar region that is thought to be derived from neurohypophyseal pituicytes. Resection of pituicytomas is often associated with significant morbidity including diabetes insipidus and
Externí odkaz:
https://doaj.org/article/a07ed27337554a038a24961991f178eb
Autor:
Joseph S. Durgin, Fraser Henderson, MacLean P. Nasrallah, Suyash Mohan, Sumei Wang, Simon F. Lacey, Jan Joseph Melenhorst, Arati S. Desai, John Y. K. Lee, Marcela V. Maus, Carl H. June, Steven Brem, Roddy S. O’Connor, Zev Binder, Donald M. O’Rourke
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Autologous chimeric antigen receptor (CAR) T cells targeted to epidermal growth factor receptor variant III (CAR T-EGFRvIII) have been developed and administered experimentally to treat patients with IDH1 wildtype recurrent glioblastoma (rGBM) (NCT02
Externí odkaz:
https://doaj.org/article/28e7edd3d6b7457386c94ed075c82476
Autor:
Angela N. Viaene, Mariarita Santi, Jason Rosenbaum, Marilyn M. Li, Lea F. Surrey, MacLean P. Nasrallah
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Mutations in SETD2 are found in many tumors, including central nervous system (CNS) tumors. Previous work has shown these mutations occur specifically in high grade gliomas of the cerebral hemispheres in pediatric and young adult patients. W
Externí odkaz:
https://doaj.org/article/e0a7fbddc85540469cc6b8c9d2edc80e