Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mackenzie Sober"'
Autor:
Alvaro G. Alvarado, Kaleab Tessema, Sree Deepthi Muthukrishnan, Mackenzie Sober, Riki Kawaguchi, Dan R. Laks, Aparna Bhaduri, Vivek Swarup, David A. Nathanson, Daniel H. Geschwind, Steven A. Goldman, Harley I. Kornblum
Publikováno v:
Cancer Res Commun
Analysis of tumor gene expression is an important approach for the classification and identification of therapeutic vulnerabilities. However, targeting glioblastoma (GBM) based on molecular subtyping has not yet translated into successful therapies.
Autor:
Harley I. Kornblum, Steven A. Goldman, Daniel H. Geschwind, David A. Nathanson, Vivek Swarup, Aparna Bhaduri, Dan R. Laks, Riki Kawaguchi, Mackenzie Sober, Sree Deepthi Muthukrishnan, Kaleab Tessema, Alvaro G. Alvarado
TCGA gene ontology analysis of clusters shows differentially enriched terms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82852d29e558451cd92ef86cad14725
https://doi.org/10.1158/2767-9764.22545783
https://doi.org/10.1158/2767-9764.22545783
Autor:
Harley I. Kornblum, Steven A. Goldman, Daniel H. Geschwind, David A. Nathanson, Vivek Swarup, Aparna Bhaduri, Dan R. Laks, Riki Kawaguchi, Mackenzie Sober, Sree Deepthi Muthukrishnan, Kaleab Tessema, Alvaro G. Alvarado
Gliomasphere dataset analysis generates two clusters with clinical relevance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037a15beee142cfb3416e5b60515f483
https://doi.org/10.1158/2767-9764.22545786
https://doi.org/10.1158/2767-9764.22545786
Autor:
Harley I. Kornblum, Steven A. Goldman, Daniel H. Geschwind, David A. Nathanson, Vivek Swarup, Aparna Bhaduri, Dan R. Laks, Riki Kawaguchi, Mackenzie Sober, Sree Deepthi Muthukrishnan, Kaleab Tessema, Alvaro G. Alvarado
Validation of genelists in additional gliomasphere dataset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898ae95c36b0905aec6aa790760b9e3a
https://doi.org/10.1158/2767-9764.22545774
https://doi.org/10.1158/2767-9764.22545774
Autor:
Harley I. Kornblum, Steven A. Goldman, Daniel H. Geschwind, David A. Nathanson, Vivek Swarup, Aparna Bhaduri, Dan R. Laks, Riki Kawaguchi, Mackenzie Sober, Sree Deepthi Muthukrishnan, Kaleab Tessema, Alvaro G. Alvarado
GO terms and TF enriched in modules associated with GS clusters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515916bcba43d8f605bfc9b8852192e3
https://doi.org/10.1158/2767-9764.22545768.v1
https://doi.org/10.1158/2767-9764.22545768.v1
Autor:
Harley I. Kornblum, Steven A. Goldman, Daniel H. Geschwind, David A. Nathanson, Vivek Swarup, Aparna Bhaduri, Dan R. Laks, Riki Kawaguchi, Mackenzie Sober, Sree Deepthi Muthukrishnan, Kaleab Tessema, Alvaro G. Alvarado
Gene signatures associate differentially to cell cycle, cellular states, and cell identities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8019b839dc22057037602b97cd129bae
https://doi.org/10.1158/2767-9764.22545765
https://doi.org/10.1158/2767-9764.22545765
Autor:
Harley I. Kornblum, Steven A. Goldman, Daniel H. Geschwind, David A. Nathanson, Vivek Swarup, Aparna Bhaduri, Dan R. Laks, Riki Kawaguchi, Mackenzie Sober, Sree Deepthi Muthukrishnan, Kaleab Tessema, Alvaro G. Alvarado
Gene Lists for each PC and direction from TCGA and GS datasets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fe7e36ea2c46472bfc1c1875009c75
https://doi.org/10.1158/2767-9764.22545771
https://doi.org/10.1158/2767-9764.22545771
Autor:
Harley I. Kornblum, Steven A. Goldman, Daniel H. Geschwind, David A. Nathanson, Vivek Swarup, Aparna Bhaduri, Dan R. Laks, Riki Kawaguchi, Mackenzie Sober, Sree Deepthi Muthukrishnan, Kaleab Tessema, Alvaro G. Alvarado
Consensus clustering identifies three clusters for the TCGA dataset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67546d4820610f7f2928affb22f5170
https://doi.org/10.1158/2767-9764.22545789
https://doi.org/10.1158/2767-9764.22545789
Data from Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma
Autor:
Harley I. Kornblum, Steven A. Goldman, Daniel H. Geschwind, David A. Nathanson, Vivek Swarup, Aparna Bhaduri, Dan R. Laks, Riki Kawaguchi, Mackenzie Sober, Sree Deepthi Muthukrishnan, Kaleab Tessema, Alvaro G. Alvarado
Analysis of tumor gene expression is an important approach for the classification and identification of therapeutic vulnerabilities. However, targeting glioblastoma (GBM) based on molecular subtyping has not yet translated into successful therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0946f913f7ae9d63dd28e19b5ff0a01b
https://doi.org/10.1158/2767-9764.c.6551028
https://doi.org/10.1158/2767-9764.c.6551028
Autor:
Harley I. Kornblum, Steven A. Goldman, Daniel H. Geschwind, David A. Nathanson, Vivek Swarup, Aparna Bhaduri, Dan R. Laks, Riki Kawaguchi, Mackenzie Sober, Sree Deepthi Muthukrishnan, Kaleab Tessema, Alvaro G. Alvarado
Gene lists differentially correlate with cell cycle and stemness signatures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5556f4ff0e24c071a83a44b8195958b
https://doi.org/10.1158/2767-9764.22545780.v1
https://doi.org/10.1158/2767-9764.22545780.v1