Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mackenzie C. Spurgat"'
Publikováno v:
FEBS letters. 592(6)
Transcription factors (TFs) reprogram cell states by exerting control over gene regulatory networks and the epigenetic landscape of a cell. Artificial transcription factors (ATFs) are designer regulatory proteins comprised of modular units that can b
Autor:
Matthew J. Wleklinski, James A. Thomson, Evan A. Heiderscheit, Aseem Z. Ansari, James R. Dutton, Anna S. Kropornicka, Devesh Bhimsaria, Catherine K. Vu, Mackenzie C. Spurgat, Scott Swanson, Timothy J. Kamp, Ron Stewart, Asuka Eguchi, Igor I. Slukvin, Parameswaran Ramanathan
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Artificial transcription factors (ATFs) are precision-tailored molecules designed to bind DNA and regulate transcription in a preprogrammed manner. Libraries of ATFs enable the high-throughput screening of gene networks that trigger cell fate decisio