Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mackenzie, Geedy"'
Autor:
Laszlo, Radnai, Matthew, Surman, Madalyn, Hafenbreidel, Erica J, Young, Rebecca F, Stremel, Li, Lin, Bilel, Bdiri, Paolo, Pasetto, Xiaomin, Jin, Mackenzie, Geedy, Joni-Rae, Partridge, Aagam, Patel, Michael, Conlon, James R, Sellers, Michael D, Cameron, Gavin, Rumbaugh, Patrick R, Griffin, Theodore M, Kamenecka, Courtney A, Miller
Publikováno v:
ACS chemical biology. 16(11)
Myosin IIs, actin-based motors that utilize the chemical energy of adenosine 5'-triphosphate (ATP) to generate force, have potential as therapeutic targets. Their heavy chains differentiate the family into muscle (skeletal [SkMII], cardiac, smooth) a
Autor:
László Radnai, Theodore M. Kamenecka, Matthew David Surman, James R. Sellers, Gavin Rumbaugh, Michael D. Cameron, Xiaomin Jin, Aagam Patel, Paolo Pasetto, Mackenzie Geedy, Rebecca F Stremel, Michael Conlon, Madalyn Hafenbreidel, Courtney A. Miller, Patrick R. Griffin, Erica J. Young, Joni-Rae Partridge, Li Lin
Myosin IIs, actin-based motors that utilize the chemical energy of ATP to generate force, have potential as therapeutic targets. Their heavy chains differentiate the family into muscle (skeletal [SkMII], cardiac, smooth) and nonmuscle myosin IIs. Des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e9cecf019baf1490f144dbdfacd638d
https://doi.org/10.1101/2020.07.28.225383
https://doi.org/10.1101/2020.07.28.225383
Autor:
Lee Apostle Mcdermott, Mackenzie Geedy, David Ryan Koes, Shabber Mohammed, Melissa Boby, Richard A. Cerione, William P. Katt, Venkatakrishnan Balasubramanian, Prema Iyer
Publikováno v:
Bioorg Med Chem Lett
Allosteric inhibitors of glutaminase (GAC), such as BPTES, CB-839 and UPGL00019, have great promise as inhibitors of cancer cell growth, but potent inhibitors with drug-like qualities have been difficult to achieve. Here, a small library of GAC inhib