Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Mack H. Wu"'
Autor:
Xiaoyuan Yang, Ethan Zheng, Victor Chatterjee, Yonggang Ma, Amanda Reynolds, Nuria Villalba, Mack H. Wu, Sarah Y. Yuan
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 7, Pp n/a-n/a (2022)
Abstract Extracellular vesicles (EVs) are bioactive membrane‐encapsulated particles generated by a series of events involving membrane budding, fission and fusion. Palmitoylation, mediated by DHHC palmitoyl acyltransferases, is a lipidation reactio
Externí odkaz:
https://doaj.org/article/348d98faf0ba4a48b229796511ab1574
Autor:
Xiaoyuan Yang, Ethan Zheng, Yonggang Ma, Victor Chatterjee, Nuria Villalba, Jerome W. Breslin, Ruisheng Liu, Mack H. Wu, Sarah Y. Yuan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Renal dysfunction is one of the most common complications of septic injury. One critical contributor to septic injury-induced renal dysfunction is renal vascular dysfunction. Protein palmitoylation serves as a novel regulator of vascular fun
Externí odkaz:
https://doaj.org/article/64fd8b2390c941cda9dee29062fc04ea
Autor:
Yonggang Ma, Taylor Zabell, Alexandra Creasy, Xiaoyuan Yang, Victor Chatterjee, Nuria Villalba, Erik B. Kistler, Mack H. Wu, Sarah Y. Yuan
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Gut ischemia/reperfusion (I/R) injury is a common clinical problem associated with significant mortality and morbidities that result from systemic inflammation and remote organ dysfunction, typically acute lung injury. The mechanisms underlying the d
Externí odkaz:
https://doaj.org/article/81dd12ae3d7741d88983bfc7018d6c55
Autor:
Richard S. Beard, Xiaoyuan Yang, Jamie E. Meegan, Jonathan W. Overstreet, Clement G.Y. Yang, John A. Elliott, Jason J. Reynolds, Byeong J. Cha, Christopher D. Pivetti, David A. Mitchell, Mack H. Wu, Robert J. Deschenes, Sarah Y. Yuan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-19 (2016)
Breaking down the endothelial barrier is a hallmark of systemic inflammatory response syndrome. Here the authors show that palmitoylation, a post-translational modification of proteins, plays a critical role in altering endothelial function during in
Externí odkaz:
https://doaj.org/article/aa685ca2e0d54ba78aad1d96ea02b68e
Autor:
Jerome W. Breslin, Dayle A. Daines, Travis M. Doggett, Kristine H. Kurtz, Flavia M. Souza‐Smith, Xun E. Zhang, Mack H. Wu, Sarah Y. Yuan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 4 (2016)
BackgroundMicrovascular leakage of plasma proteins is a hallmark of inflammation that leads to tissue dysfunction. There are no current therapeutic strategies to reduce microvascular permeability. The purpose of this study was to identify the role of
Externí odkaz:
https://doaj.org/article/e28ff2eab82a4a2abec0964b685f2381
Publikováno v:
Immunology Letters. 254:41-53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0562504f66043616ec5f05fd108e5cf
https://doi.org/10.1016/j.imlet.2023.02.001
https://doi.org/10.1016/j.imlet.2023.02.001
Supplementary Figure S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744eafb554621c6925b55e3979c2600f
https://doi.org/10.1158/1541-7786.22519252
https://doi.org/10.1158/1541-7786.22519252
Autor:
Yonggang Ma, Xiaoyuan Yang, Nuria Villalba, Victor Chatterjee, Amanda Reynolds, Sam Spence, Mack H. Wu, Sarah Y. Yuan
Publikováno v:
Am J Physiol Heart Circ Physiol
Some patients with myocardial infarction (MI) exhibit lymphopenia, a reduction in blood lymphocyte count. Moreover, lymphopenia inversely correlates with patient prognosis. The objective of this study was to elucidate the underlying mechanisms that c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd038a86aadc953da5809516bff95a75
https://doi.org/10.1152/ajpheart.00003.2022
https://doi.org/10.1152/ajpheart.00003.2022
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 319:H1181-H1196
Extracellular vesicles (EVs) have attracted rising interests in the cardiovascular field not only because they serve as serological markers for circulatory disorders but also because they participate in important physiological responses to stress and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141d9dfb46a755d85c1aa56d63c5feb4
https://doi.org/10.1152/ajpheart.00579.2020
https://doi.org/10.1152/ajpheart.00579.2020
Autor:
Richard S. Beard, Travis S. Wertz, Julia Thom Oxford, Jamie E. Meegan, Byeong J. Cha, Sarah Y. Yuan, Xiaoyuan Yang, Mack H. Wu, Brian A Hoettels
Publikováno v:
J Cereb Blood Flow Metab
Inflammation-induced blood–brain barrier (BBB) dysfunction and microvascular leakage are associated with a host of neurological disorders. The tight junction protein claudin-5 (CLDN5) is a crucial protein necessary for BBB integrity and maintenance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050d773c5188d56e0335cb46eb277d71
https://doi.org/10.1177/0271678x18817512
https://doi.org/10.1177/0271678x18817512