Zobrazeno 1 - 10
of 1 110
pro vyhledávání: '"Macitentan"'
Autor:
Richard Channick, Kelly M. Chin, Vallerie V. McLaughlin, Matthew R. Lammi, Roham T. Zamanian, Stefano Turricchia, Rose Ong, Lada Mitchell, Nick H. Kim
Publikováno v:
Cardiology and Therapy, Vol 13, Iss 2, Pp 315-339 (2024)
Abstract Introduction Data on real-world clinical practice and outcomes of patients with pulmonary arterial hypertension associated with connective tissue disease (CTD-PAH) are scarce. The OPUS/OrPHeUS studies enrolled patients newly initiating macit
Externí odkaz:
https://doaj.org/article/c4b19ee288354c6089965ac76ad5d6fa
Autor:
Jennifer Lynn Ford, Ahad Sabet, Jaya Natarajan, Hans Stieltjes, Daniel L. Chao, Navin Goyal, Denes Csonka
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract The primary aim was to demonstrate bioequivalence between the 10/20 mg fixed‐dose combination (FDC) of macitentan/tadalafil in a single tablet and the free combination of both drugs, and to evaluate the food effect on the 10/20 mg FDC in h
Externí odkaz:
https://doaj.org/article/9f9481ba906943d08acf091610bbda6a
Autor:
Nick H. Kim, Kelly M. Chin, Vallerie V. McLaughlin, Hilary DuBrock, Ricardo Restrepo-Jaramillo, Zeenat Safdar, Gwen MacDonald, Nicolas Martin, Daniel Rosenberg, Maria Solonets, Richard Channick
Publikováno v:
Pulmonary Therapy, Vol 10, Iss 1, Pp 85-107 (2024)
Abstract Introduction Portopulmonary hypertension (PoPH) carries a worse prognosis than other forms of pulmonary arterial hypertension (PAH). Data regarding use of PAH-specific therapies in patients with PoPH are sparse as they are usually excluded f
Externí odkaz:
https://doaj.org/article/d2d527f021da4bc98cd27bae7d4bdc4e
Autor:
Adam Torbicki, Richard Channick, Nazzareno Galiè, David G. Kiely, Pamela Moceri, Andrew Peacock, Andrew J. Swift, Ahmed Tawakol, Anton Vonk Noordegraaf, Dayana Flores, Nicolas Martin, Stephan Rosenkranz
Publikováno v:
Cardiology and Therapy, Vol 13, Iss 1, Pp 173-190 (2024)
Abstract Introduction The aim of this sub-study was to evaluate the relationship between echocardiography (echo) and cardiac magnetic resonance imaging (cMRI) variables and to utilize echo to assess the effect of macitentan on right ventricle (RV) st
Externí odkaz:
https://doaj.org/article/7df83afa62ac49a88624dd7ed2aeb16a
Autor:
Dan Du, Ya‐Dong Yuan
Publikováno v:
The Clinical Respiratory Journal, Vol 17, Iss 11, Pp 1117-1129 (2023)
Abstract Introduction Our purpose of this study is to evaluate the effect and safety of macitentan in the treatment of pulmonary hypertension (PH). Methods We retrieved the safety and efficacy of macitentan treatment for PH using PubMed, the Cochrane
Externí odkaz:
https://doaj.org/article/e7c36154023c4942a8eb1e62054aad15
Autor:
Niuniu Li, Qiang Wu, Juan Meng, Cheng Feng, Siwei Jiang, Meixia Chen, Wenhui Xu, Fei Wang, Yifan Zhang, Juncai Liu, Cheng Xu, Gaolin Liu, Hong Gao
Publikováno v:
ESC Heart Failure, Vol 10, Iss 4, Pp 2718-2721 (2023)
Abstract Pulmonary arterial hypertension‐targeted therapies in portopulmonary hypertension (PoPH) are scarce, let alone for patients with chronic liver failure (CLF) and hepatopulmonary syndrome (HPS). A 48‐year male was admitted to the hospital
Externí odkaz:
https://doaj.org/article/5a7acfabf0454c169c05bb6f296b21d3
Publikováno v:
Respiratory Medicine Case Reports, Vol 50, Iss , Pp 102058- (2024)
A 69-year-old woman was diagnosed with idiopathic interstitial pneumonia (IIP). The patient underwent a combination therapy of steroid therapy and intravenous cyclophosphamide, long-term oxygen therapy, and the initiation of Nintedanib. However, ther
Externí odkaz:
https://doaj.org/article/3b5754b9a6414f399b55a65b8adb0a04
Autor:
Rutger G.T. Feenstra, Tijn P.J. Jansen, S. Matthijs Boekholdt, Janet E. Brouwer, Margriet I. Klees, Yolande Appelman, Marianne E. Wittekoek, Tim P. van de Hoef, Robbert J. de Winter, Jan J. Piek, Peter Damman, Marcel A.M. Beijk
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 47, Iss , Pp 101238- (2023)
Background: Treatment of patients diagnosed with angina due to epicardial or microvascular coronary artery spasm (CAS) is challenging because patients often remain symptomatic despite conventional pharmacological therapy. In this prospective, randomi
Externí odkaz:
https://doaj.org/article/685e63c4419245b7bcd2d462505cf75d
Autor:
Jia Xu, Quan Zhou, Pengjiao Hou, Yu Wang, Peiwu Geng, Zebei Lu, Yunfang Zhou, Dapeng Dai, Shuanghu Wang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Macitentan was approved by the United States Food and Drug Administration (FDA) in 2013 for the treatment of pulmonary arterial hypertension (PAH). Bergapten is a furanocoumarin that is abundant in Umbelliferae and Rutaceae plants and is widely used
Externí odkaz:
https://doaj.org/article/6bc762214fae496baf37289bbb8c8860
Autor:
Bindu Kodati, Wei Zhang, Shaoqing He, Jennifer H. Pham, Kallen J. Beall, Zoe E. Swanger, Vignesh R. Krishnamoorthy, Payton E. Harris, Trent Hall, Ashley V. Tran, Renuka M. Chaphalkar, Sai H. Chavala, Dorota L. Stankowska, Raghu R. Krishnamoorthy
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
Glaucoma is a chronic and progressive eye disease, commonly associated with elevated intraocular pressure (IOP) and characterized by optic nerve degeneration, cupping of the optic disc, and loss of retinal ganglion cells (RGCs). The pathological chan
Externí odkaz:
https://doaj.org/article/f2522abd446f495f99a0514810f26e8c