Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maciej Zadrozny"'
Autor:
Karima Schwab, Dilyara Lauer, Mandy Magbagbeolu, Franz Theuring, Anna Gasiorowska, Maciej Zadrozny, Charles R. Harrington, Claude M. Wischik, Grażyna Niewiadomska, Gernot Riedel
Publikováno v:
Brain Research Bulletin, Vol 212, Iss , Pp 110955- (2024)
In clinical trials for Alzheimer’s disease (AD), hydromethylthionine mesylate (HMTM) showed reduced efficacy when administered as an add-on to symptomatic treatments, while it produced a significant improvement of cognitive function when taken as m
Externí odkaz:
https://doaj.org/article/55dcde6ffee8464392a774ea753330c1
Autor:
Maciej Zadrozny, Patrycja Drapich, Anna Gasiorowska-Bien, Wiktor Niewiadomski, Charles R. Harrington, Claude M. Wischik, Gernot Riedel, Grazyna Niewiadomska
Publikováno v:
Cells, Vol 13, Iss 7, p 642 (2024)
Basal forebrain cholinergic dysfunction, most likely linked with tau protein aggregation, is a characteristic feature of Alzheimer’s disease (AD). Recent evidence suggests that tau protein is a putative target for the treatment of dementia, and the
Externí odkaz:
https://doaj.org/article/08f2654462fb4a6f97b2a4c2ca2ac9d8
Autor:
Anna Gasiorowska, Malgorzata Wydrych, Patrycja Drapich, Maciej Zadrozny, Marta Steczkowska, Wiktor Niewiadomski, Grazyna Niewiadomska
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The elderly population is growing worldwide, with important health and socioeconomic implications. Clinical and experimental studies on aging have uncovered numerous changes in the brain, such as decreased neurogenesis, increased synaptic defects, gr
Externí odkaz:
https://doaj.org/article/15cf23004a754c6dac0ccaf32c97a27d
Autor:
Renato X. Santos, Dilyara Lauer, Mandy Magbagbeolu, Constantin Kondak, Franz Theuring, Karima Schwab, Marta Steczkowska, Maciej Zadrozny, Malgorzata Wydrych, Charles R. Harrington, Claude M. Wischik, Gernot Riedel, Anna Cranston, Grazyna Niewiadomska, Jochen Klein, Valeria Melis
Publikováno v:
Current Alzheimer Research
Background: Symptomatic treatments of Alzheimer’s Disease (AD) with cholinesterase inhibitors and/or memantine are relatively ineffective and there is a need for new treatments targeting the underlying pathology of AD. In most of the failed disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d6a2554e6d21aa1d5fe5a69a8cf746
https://doi.org/10.2174/1567205017666200224120926
https://doi.org/10.2174/1567205017666200224120926
Autor:
Grazyna Niewiadomska, Wiktor Niewiadomski, Marta Steczkowska, Anna Gasiorowska, Maciej Zadrozny, Claude M. Wischik, Gernot Riedel, Malgorzata Wydrych
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53a0de976b65487cc50d11cbc6dc6bf8
https://doi.org/10.1002/alz.042986
https://doi.org/10.1002/alz.042986
Autor:
Claude M. Wischik, Grazyna Niewiadomska, Gernot Riedel, Anna Cranston, Maciej Zadrozny, Franz Theuring, Charles R. Harrington, Ewelina Palasz, Adrianna Wysocka, Marta Steczkowska
Publikováno v:
Brain Communications
An early and sizeable loss of basal forebrain cholinergic neurons is a well-characterized feature associated with measurable deficits in spatial learning and cognitive impairment in patients with Alzheimer’s disease. In addition, pro-inflammatory g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beddeeddee211eb3888785bf7333fd04
https://doi.org/10.1093/braincomms/fcaa033
https://doi.org/10.1093/braincomms/fcaa033
Autor:
Ewelina Palasz, James Hyatt, Maciej Zadrozny, Marta Steczkowska, Radoslaw Folcik, Adrianna Wysocka, Grazyna Niewiadomska
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f64c5b828934374301fb89c2abf0ad96
https://doi.org/10.1016/j.jalz.2017.06.017
https://doi.org/10.1016/j.jalz.2017.06.017