Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Maciej Wieczorek"'
Autor:
Aleksandra Rzewińska, Jakub Szlęk, Damian Dąbrowski, Ewelina Juszczyk, Katarzyna Mróz, Heikki Räikkönen, Mia Siven, Maciej Wieczorek, Przemysław Dorożyński
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1157 (2024)
The pursuit of targeted therapies for cytokine-dependent diseases has led to the discovery of Janus kinase (JAK) inhibitors, a promising class of drugs. Among them, CPL409116, a selective dual JAK and rho-associated protein kinase inhibitor (ROCK), h
Externí odkaz:
https://doaj.org/article/6049c0b9f7b84a35a5814f9bec6fdeb6
Publikováno v:
Energy Reports, Vol 9, Iss , Pp 766-773 (2023)
This paper describes test results of two sets of VRLA GEL batteries that included various phenomena which might accelerate their degradation process in off-grid PV systems like: incomplete charges (bad recharges), low start current and remaining in p
Externí odkaz:
https://doaj.org/article/5d764cff66ce4a7d8e7e3a50303e42b7
Publikováno v:
Energy Reports, Vol 9, Iss , Pp 106-115 (2023)
This paper describes method of design and control of a hybrid battery built with lead–acid and lithium-ion batteries. In the proposed hybrid, bidirectional interleaved DC/DC converter is integrated with lithium-ion battery, and is an interface for
Externí odkaz:
https://doaj.org/article/cf70a815d1ae460ea776a62b893b7145
Autor:
Delfina Popiel, Aleksandra Stańczak, Monika Skupińska, Agata Mikołajczyk, Paulina Stańczak, Filip Mituła, Joanna Hucz-Kalitowska, Kinga Jastrzębska, Damian Smuga, Jakub Dominowski, Monika Delis, Krzysztof Mulewski, Wojciech Pietruś, Daria Zdżalik-Bielecka, Karolina Dzwonek, Monika Lamparska-Przybysz, Abdellah Yamani, Patrycja Olejkowska, Natalia Piórkowska, Krzysztof Dubiel, Maciej Wieczorek, Jerzy Pieczykolan
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Fibroblast Growth Factor Receptors (FGFRs) are a family of receptor tyrosine kinases expressed on a plethora of cell membranes. They play crucial roles in both embryonic development and adult tissue functions. There is an increasing amount of evidenc
Externí odkaz:
https://doaj.org/article/07e91621f37e47a8ab05a2c584ceb012
Autor:
Katarzyna Ojrzyńska, Maciej Wieczorek
Disability and Dissensus is a comprehensive collection of essays that reflects the interdisciplinary nature of critical cultural disability studies. The volume offers a selection of texts by numerous specialists in different areas of the humanities,
Autor:
Anna Piotrowska, Joanna I. Nowak, Justyna M. Wierzbicka, Paweł Domżalski, Monika Górska-Arcisz, Rafał Sądej, Delfina Popiel, Maciej Wieczorek, Michał A. Żmijewski
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2505 (2024)
Regardless of the unprecedented progress in malignant melanoma treatment strategies and clinical outcomes of patients during the last twelve years, this skin cancer remains the most lethal one. We have previously documented that vitamin D and its low
Externí odkaz:
https://doaj.org/article/cd4871655fd5413fb904b490adba7e7f
Autor:
Lidia Gurba-Bryśkiewicz, Wioleta Maruszak, Damian A. Smuga, Krzysztof Dubiel, Maciej Wieczorek
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2752 (2023)
The successful development of nonviral delivery systems for nucleic acids has been reported extensively over the past years. Increasingly employed to improve the delivery efficiency and therapeutic efficacy of RNA are lipid nanoparticles (LNPs). Many
Externí odkaz:
https://doaj.org/article/17c6955924224311a5546027e7673973
Autor:
Mikolaj Matloka, Sylwia Janowska, Piotr Pankiewicz, Sofiya Kokhanovska, Tomasz Kos, Małgorzata Hołuj, Izabela Rutkowska-Wlodarczyk, Krzysztof Abramski, Monika Janicka, Piotr Jakubowski, Maciej Świątkiewicz, Marlena Welniak-Kaminska, Joanna Hucz-Kalitowska, Paulina Dera, Lukasz Bojarski, Paweł Grieb, Piotr Popik, Maciej Wieczorek, Jerzy Pieczykolan
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Phosphodiesterase 10A (PDE10A) is expressed almost exclusively in the striatum and its inhibition is suggested to offer potential treatment in disorders associated with basal ganglia. We evaluated the selectivity, cytotoxicity, genotoxici
Externí odkaz:
https://doaj.org/article/d453e3c4687c448496b544e69c14dfd4
Autor:
Maria Dulak-Lis, Anna Bujak, Kamila Gala, Martyna Banach, Urszula Kędzierska, Joanna Miszkiel, Joanna Hucz-Kalitowska, Michał Mroczkiewicz, Bartosz Stypik, Krzysztof Szymczak, Paweł Gunerka, Krzysztof Dubiel, Beata M. Zygmunt, Maciej Wieczorek, Jerzy S. Pieczykolan
Publikováno v:
Journal of Pharmacological Sciences, Vol 145, Iss 4, Pp 340-348 (2021)
Systemic lupus erythematosus is a chronic inflammatory disease, in which treatment is still limited due to suboptimal efficacy and toxicities associated with the available therapies. JAK kinases are well known to play an important role in systemic lu
Externí odkaz:
https://doaj.org/article/68149f6ba7294e63ad8e5e6d2edd988c
Autor:
Wojciech Pietruś, Mariola Stypik, Marcin Zagozda, Martyna Banach, Lidia Gurba-Bryśkiewicz, Wioleta Maruszak, Arkadiusz Leniak, Rafał Kurczab, Zbigniew Ochal, Krzysztof Dubiel, Maciej Wieczorek
Publikováno v:
Molecules, Vol 28, Iss 8, p 3531 (2023)
As a member of the class I PI3K family, phosphoinositide 3-kinase δ (PI3Kδ) is an important signaling biomolecule that controls immune cell differentiation, proliferation, migration, and survival. It also represents a potential and promising therap
Externí odkaz:
https://doaj.org/article/62c0899b09d24354ba8846e2be2ab71f