Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Maciej T Lazarewicz"'
Autor:
Samuel A Neymotin, Markus M Hilscher, Thiago C Moulin, Yosef Skolnick, Maciej T Lazarewicz, William W Lytton
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76285 (2013)
Ih channels are uniquely positioned to act as neuromodulatory control points for tuning hippocampal theta (4-12 Hz) and gamma (25 Hz) oscillations, oscillations which are thought to have importance for organization of information flow. contributes to
Externí odkaz:
https://doaj.org/article/3a42564e469a4557b4c895725c7462e4
Autor:
Maciej T. Lazarewicz, Leif H. Finkel, Michael J. Gandal, Richard S. Ehrlichman, Steven J. Siegel, Christina R. Maxwell
Publikováno v:
Journal of Cognitive Neuroscience. 22:1452-1464
Ketamine, an N-methyl-d-aspartate (NMDA) receptor glutamatergic antagonist, has been studied as a model of schizophrenia when applied in subanesthetic doses. In EEG studies, ketamine affects sensory gating and alters the oscillatory characteristics o
Publikováno v:
Journal of Neurophysiology. 102:2342-2357
There is great interest in the role of coherent oscillations in the brain. In some cases, high-frequency oscillations (HFOs) are integral to normal brain function, whereas at other times they are implicated as markers of epileptic tissue. Mechanisms
Autor:
Steve J. Siegel, Maciej T. Lazarewicz, Christina R. Maxwell, Michael J. Gandal, Leif H. Finkel, Richard S. Ehrlichman, Bruce I. Turetsky, Diego Contreras
Publikováno v:
Neuroscience. 158:705-712
Introduction: Electrophysiological responses to auditory stimuli have provided a useful means of elucidating mechanisms and evaluating treatments in psychiatric disorders. Deficits in gating during paired-click tasks and lack of mismatch negativity f
Publikováno v:
Neurocomputing. 69:1025-1029
We analyze the parameter ranges under which the voltage in a dendritic cable model exhibits bistability. We find (1) the magnitude of NMDA and GABA conductances limit the maximum cable diameter for which the system is bistable. For the investigated p
Autor:
Maciej T. Lazarewicz, John A. Wolf, Jason T. Moyer, Marianne Benoit-Marand, Patricio O'Donnell, Leif H. Finkel, Diego Contreras
Publikováno v:
The Journal of Neuroscience. 25:9080-9095
We describe a computational model of the principal cell in the nucleus accumbens (NAcb), the medium spiny projection (MSP) neuron. The model neuron, constructed in NEURON, includes all of the known ionic currents in these cells and receives synaptic
Publikováno v:
The Journal of Comparative Neurology. 473:177-193
The dendritic trees of hippocampal pyramidal cells play important roles in the establishment and regulation of network connectivity, synaptic plasticity, and firing dynamics. Several laboratories routinely reconstruct CA3 and CA1 dendrites to correla
Publikováno v:
Biosystems. 67:129-137
We introduce a novel computational model of hippocampal pyramidal cells physiology based on an up-to-date, detailed description of passive and active biophysical properties and real dendritic morphology. This model constitutes a modification of a pre
Correction: Ih Tunes Theta/Gamma Oscillations and Cross-Frequency Coupling In an In Silico CA3 Model
Autor:
Thiago C. Moulin, Samuel A. Neymotin, William W. Lytton, Markus M. Hilscher, Maciej T. Lazarewicz, Yosef Skolnick
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12 (2013)
PLoS ONE, Vol 8, Iss 12 (2013)
This article was republished on December 5th, 2013 because of missing mathematical symbols. Please download this article again to view the correct content.
Autor:
Paul H. Stypulkowski, Ankit N. Khambhati, Jon Giftakis, Maciej T. Lazarewicz, Randy M. Jensen, Siddharth Dani, Scott R. Stanslaski, Pedram Afshar, Dave Linde, Peng Cong, David L. Carlson, Timothy J. Denison
Publikováno v:
Scopus-Elsevier
Frontiers in Neural Circuits, Vol 6 (2013)
Frontiers in Neural Circuits
Frontiers in Neural Circuits, Vol 6 (2013)
Frontiers in Neural Circuits
While modulating neural activity through stimulation is an effective treatment for neurological diseases such as Parkinson’s disease and essential tremor, an opportunity for improving neuromodulation therapy remains in automatically adjusting thera