Výsledky vyhledávání - "Maciej Sobczak"

Akademický článek

I-CBP112 declines overexpression of ATP-binding cassette transporters and sensitized drug-resistant MDA-MB-231 and A549 cell lines to chemotherapy drugs

Autor: Magdalena Strachowska, Karolina Gronkowska, Maciej Sobczak, Marika Grodzicka, Sylwia Michlewska, Kinga Kołacz, Tuhin Sarkar, Joanna Korszun, Maksim Ionov, Agnieszka Robaszkiewicz

Publikováno v: Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115798- (2023)

Despite extensive efforts and ongoing progress in personalized anticancer approaches, chemotherapy remains the first line or the only treatment for some tumors that may develop resistance to chemotherapeutics in time due to inter alia overexpression

Externí odkaz: https://doaj.org/article/69462619b8e54a91966e2966d4016c5d

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Akademický článek

Continuity and change in the ceramic assemblage from Metsamor between the 10th and 7th centuries BCE (new data from the 2021 season)

Autor: Mateusz Iskra, Tigran Zakyan, Maciej Sobczak, Bartosz Placak

Publikováno v: Polish Archaeology in the Mediterranean, Vol 31, Pp 153-172 (2022)

The morphology and distribution of what is considered as a local pottery assemblage from the Iron I and Iron II phases, which in Metsamor is part of a larger cultural phenomenon designated as the Lchashen–Metsamor pottery horizon, is the subject of

Externí odkaz: https://doaj.org/article/a607efc5c7ff4cafa7a2fdacc869d9bf

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Akademický článek

LSD1 Facilitates Pro-Inflammatory Polarization of Macrophages by Repressing Catalase

Autor: Maciej Sobczak, Magdalena Strachowska, Karolina Gronkowska, Iwona Karwaciak, Łukasz Pułaski, Agnieszka Robaszkiewicz

Publikováno v: Cells, Vol 10, Iss 9, p 2465 (2021)

The increased level of hydrogen peroxide accompanies some modes of macrophage specification and is linked to ROS-based antimicrobial activity of these phagocytes. In this study, we show that activation of toll-like receptors with bacterial components

Externí odkaz: https://doaj.org/article/ff293378f450475db03860779a1582ee

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Akademický článek

The Role of PARP1 in Monocyte and Macrophage Commitment and Specification: Future Perspectives and Limitations for the Treatment of Monocyte and Macrophage Relevant Diseases with PARP Inhibitors

Autor: Maciej Sobczak, Marharyta Zyma, Agnieszka Robaszkiewicz

Publikováno v: Cells, Vol 9, Iss 9, p 2040 (2020)

Modulation of PARP1 expression, changes in its enzymatic activity, post-translational modifications, and inflammasome-dependent cleavage play an important role in the development of monocytes and numerous subtypes of highly specialized macrophages. T

Externí odkaz: https://doaj.org/article/2591b9f82e3a438fada08793152afb3a

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Akademický článek

MONITOROWANIE PARAMETRÓW TERMICZNYCH PROCESU TWARDNIENIA BETONÓW OSŁONOWYCH

Autor: Roman JASKULSKI, Michał A. GLINICKI, Mariusz DĄBROWSKI, Zbigniew RANACHOWSKI, Maciej SOBCZAK

Publikováno v: Journal of Civil Engineering, Environment and Architecture (2016)

W artykule przedstawiono wyniki badań parametrów termicznych procesu twardnienia mieszanek betonowych, z których dwie wykonano z wykorzystaniem kruszyw stosowanych w produkcji betonów osłonowych (kruszywo magnetytowe oraz serpentynitowe), a trze

Externí odkaz: https://doaj.org/article/2dc9c807302042c888c816203d174da4

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A brief dive into the phenomenon of cisplatin resistance in non-small-cell lung cancer

Autor: Maciej Sobczak

Publikováno v: Acta Universitatis Lodziensis. Folia Biologica et Oecologica. 17:37-41

Lung cancer is one of the most lethal types of cancer due to a lack of proper treatment. The rare presence of molecular therapy targets forces the use of platinum-based drugs. Cisplatin, approved by the USA as an anticancer therapy in the 1970s, is s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a802cba2500f4b575631eabb6a6e003e
https://doi.org/10.18778/1730-2366.16.12

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Activation of

Autor: Maciej, Sobczak, Magdalena, Strachowska, Karolina, Gronkowska, Agnieszka, Robaszkiewicz

Publikováno v: Cancers. 14(4)

Although cisplatin-based therapies are common among anticancer approaches, they are often associated with the development of cancer drug resistance. This phenomenon is, among others, caused by the overexpression of ATP-binding cassette, membrane-anch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e832f23350569f39cc9e742d196c5210
https://pubmed.ncbi.nlm.nih.gov/35205642

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