Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Maciej Siedlar"'
Autor:
Izabela Siemińska, Karolina Bukowska-Strakova, Marcin Surmiak, Katarzyna Ptak, Izabela Szymońska, Anna Olchawa-Czech, Nina Mól, Przemysław Błyszczuk, Marek Sanak, Jarek Baran, Przemko Kwinta, Maciej Siedlar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The etiology of multisystem inflammatory syndrome in children (MIS-C), frequently observed following COVID-19 infection, remains elusive. This study unveils insights derived from cytokine analysis in the sera of MIS-C patients, both before a
Externí odkaz:
https://doaj.org/article/a2761f74d4574f17ad2e2ecd1a06203f
Autor:
Ismael Rodriguez, Justyna Kocik-Krol, Lukasz Skalniak, Bogdan Musielak, Aneta Wisniewska, Agnieszka Ciesiołkiewicz, Łukasz Berlicki, Jacek Plewka, Przemyslaw Grudnik, Malgorzata Stec, Maciej Siedlar, Tad A. Holak, Katarzyna Magiera-Mularz
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-8 (2023)
Abstract Recent advances in immuno-oncology have opened up new and impressive treatment options for cancer. Notwithstanding, overcoming the limitations of the current FDA-approved therapies with monoclonal antibodies (mAbs) that block the PD-1/PD-L1
Externí odkaz:
https://doaj.org/article/4d89b666a61e477c85c3abb086044bda
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-20 (2023)
Abstract According to the World Health Organization (WHO), air pollution is one of the most serious threats for our planet. Despite a growing public awareness of the harmful effects of air pollution on human health, the specific influence of particul
Externí odkaz:
https://doaj.org/article/d5376f9ec09d433189f33b51282e2c8f
Autor:
Karolina Tkacz, Filip Rolski, Monika Stefańska, Kazimierz Węglarczyk, Rafał Szatanek, Maciej Siedlar, Gabriela Kania, Przemysław Błyszczuk
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5579 (2024)
Myocarditis is characterized by an influx of inflammatory cells, predominantly of myeloid lineage. The progression of myocarditis to a dilated cardiomyopathy is markedly influenced by TGF-β signalling. Here, we investigate the role of TGF-β signall
Externí odkaz:
https://doaj.org/article/600e78872fe34f758ed41a10513e678f
Autor:
Magdalena Rutkowska-Zapała, Agnieszka Grabowska-Gurgul, Marzena Lenart, Anna Szaflarska, Anna Kluczewska, Monika Mach-Tomalska, Monika Baj-Krzyworzeka, Maciej Siedlar
Publikováno v:
Cells, Vol 13, Iss 5, p 417 (2024)
Selective IgA deficiency (SIgAD) is the most common form and common variable immunodeficiency (CVID) is the most symptomatic form of predominant antibody deficiency. Despite differences in the clinical picture, a similar genetic background is suggest
Externí odkaz:
https://doaj.org/article/0216ca46e5ad4d01893d7297323fb342
Autor:
Jessica Catapano, Marcin Luty, Tomasz Wróbel, Maciej Pudełek, Katarzyna Piwowarczyk, Sylwia Kędracka-Krok, Maciej Siedlar, Zbigniew Madeja, Jarosław Czyż
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-19 (2022)
Abstract Background Metformin is an inhibitor of oxidative phosphorylation that displays an array of anticancer activities. The interference of metformin with the activity of multi-drug resistance systems in cancer cells has been reported. However, t
Externí odkaz:
https://doaj.org/article/10d26827c51d47bcb480ad68f24bfa43
Autor:
Marzena Lenart, Magdalena Górecka, Michal Bochenek, Emilia Barreto-Duran, Artur Szczepański, Adrianna Gałuszka-Bulaga, Natalia Mazur-Panasiuk, Kazimierz Węglarczyk, Andżelika Siwiec-Koźlik, Mariusz Korkosz, Paweł P. Łabaj, Monika Baj-Krzyworzeka, Maciej Siedlar, Krzysztof Pyrc
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNatural killer (NK) cells plays a pivotal role in the control of viral infections, and their function depend on the balance between their activating and inhibitory receptors. The immune dysregulation observed in COVID-19 patients was prev
Externí odkaz:
https://doaj.org/article/e353219de69b4ec48c032644a458726a
Autor:
Małgorzata Stec, Marcin Czepiel, Marzena Lenart, Agata Piestrzyńska-Kajtoch, Jacek Plewka, Agnieszka Bieniek, Kazimierz Węglarczyk, Rafał Szatanek, Magdalena Rutkowska-Zapała, Zofia Guła, Anna Kluczewska, Jarosław Baran, Mariusz Korkosz, Maciej Siedlar
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Spondyloarthropathies (SpA) are a family of rheumatic disorders that could be divided into axial (axSpA) and peripheral (perSpA) sub-forms depending on the disease clinical presentation. The chronic inflammation is believed to be driven by innate imm
Externí odkaz:
https://doaj.org/article/2e45dadd69084395a81fb52427754be3
Autor:
Emilia Barreto-Duran, Artur Szczepański, Adrianna Gałuszka-Bulaga, Marcin Surmiak, Maciej Siedlar, Marek Sanak, Zenon Rajfur, Aleksandra Milewska, Marzena Lenart, Krzysztof Pyrć
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The first line of antiviral immune response in the lungs is secured by the innate immunity. Several cell types take part in this process, but airway macrophages (AMs) are among the most relevant ones. The AMs can phagocyte infected cells and activate
Externí odkaz:
https://doaj.org/article/03406eef012b4d8b8cc826da9d869cf4
Autor:
Małgorzata Stec, Michał Seweryn, Mariusz Korkosz, Zofia Guła, Rafał Szatanek, Kazimierz Węglarczyk, Magdalena Rutkowska-Zapała, Marzena Lenart, Marcin Czepiel, Jarosław Czyż, Jarosław Baran, Anna Gruca, Kamila Wojnar-Lasoń, Paweł Wołkow, Maciej Siedlar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Spondyloarthritis (SpA) is characterized by chronic inflammation and structural damage involving spine and peripheral joints. Monocytes, as part of innate immune system, following migration into affected tissue, may play a role in the pathog
Externí odkaz:
https://doaj.org/article/867ae2a3626743fc95376b2edc87c722