Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Maciej Maslyk"'
Autor:
Olga Ciupak, Mateusz Daśko, Karol Biernacki, Janusz Rachon, Maciej Masłyk, Konrad Kubiński, Aleksandra Martyna, Sebastian Demkowicz
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 239-248 (2021)
In the present work, we report a new class of potent steroid sulphatase (STS) inhibitors based on 6-(1-phenyl-1H-1,2,3-triazol-4-yl)naphthalen-2-yl sulphamate derivatives. Within the set of new STS inhibitors, 6-(1-(1,2,3-trifluorophenyl)-1H-1,2,3-tr
Externí odkaz:
https://doaj.org/article/1d8fdeadde00449b96ff653055b93fa6
Autor:
Mateusz Daśko, Sebastian Demkowicz, Karol Biernacki, Olga Ciupak, Witold Kozak, Maciej Masłyk, Janusz Rachon
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1163-1184 (2020)
The purpose of this review article is to provide an overview of recent achievements in the synthesis of novel steroid sulphatase (STS) inhibitors. STS is a crucial enzyme in the biosynthesis of active hormones (including oestrogens and androgens) and
Externí odkaz:
https://doaj.org/article/f089a2247d0c42ee9b6e9c28a518045c
Autor:
Agnieszka Łubek-Nguyen, Marta Olech, Natalia Nowacka-Jechalke, Aleksandra Martyna, Konrad Kubiński, Maciej Masłyk, Marcin Moczulski, Sebastian Kanak
Publikováno v:
Applied Sciences, Vol 12, Iss 19, p 10126 (2022)
Rosa rugosa Thunb. (Rosaceae) plantations can provide industrial amounts of roots, which contain many biologically active metabolites. Here, we report the first studies of the chemical composition and pharmacological potential of a crude polysacchari
Externí odkaz:
https://doaj.org/article/649d5a6aa0c7427fbbabaa4b5ad7aa69
Autor:
Joanna Kowalczuk, Andrzej Łapiński, Elżbieta Stolarczyk, Oleg M. Demchuk, Konrad Kubiński, Monika Janeczko, Aleksandra Martyna, Maciej Masłyk, Sylwia Turczyniak-Surdacka
Publikováno v:
Molecules, Vol 26, Iss 24, p 7462 (2021)
An aqueous solution of sodium citrate stabilized gold nanoparticles (AuNP) in the presence of N-lauroyl-L-alanine (C12ALA) forms a stable gel. The structure of the gel and the distribution profile of AuNP in it were analyzed. Will nanoparticles separ
Externí odkaz:
https://doaj.org/article/73d0f26dfd334af2a3d5dfdeae904ebf
Autor:
Aleksandra Martyna, Maciej Masłyk, Monika Janeczko, Elżbieta Kochanowicz, Bartłomiej Gielniewski, Aleksandra Świercz, Oleg M. Demchuk, Konrad Kubiński
Publikováno v:
Molecules, Vol 25, Iss 12, p 2928 (2020)
In the light of the increasing occurrence of antifungal resistance, there is an urgent need to search for new therapeutic strategies to overcome this phenomenon. One of the applied approaches is the synthesis of small-molecule compounds showing antif
Externí odkaz:
https://doaj.org/article/4566ef9454d944bd8916c4a1fb69f8c1
Autor:
Regina Martínez, Bruno Di Geronimo, Miryam Pastor, José María Zapico, Claire Coderch, Rostyslav Panchuk, Nadia Skorokhyd, Maciej Maslyk, Ana Ramos, Beatriz de Pascual-Teresa
Publikováno v:
Molecules, Vol 25, Iss 7, p 1497 (2020)
The design of multitarget drugs (MTDs) has become an innovative approach for the search of effective treatments in complex diseases such as cancer. In this work, we communicate our efforts in the design of multi-targeting histone deacetylase (HDAC) a
Externí odkaz:
https://doaj.org/article/97dcdbbdeeea4f3e813fe51907d076c3
Autor:
Ana Ramos, Maciej Maslyk, Jose Maria Zapico, Robert Swider, Sonsoles Martin-Santamaria, Beatriz de Pascual-Teresa
Publikováno v:
ARKIVOC, Vol 2011, Iss 3, Pp 54-71 (2010)
Externí odkaz:
https://doaj.org/article/13c6a0ab53924e27b413bc8038175503
Autor:
Maciej Masłyk, Tomasz Lenard, Marta Olech, Aleksandra Martyna, Małgorzata Poniewozik, Anna Boguszewska-Czubara, Elżbieta Kochanowicz, Paweł Czubak, Konrad Kubiński
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Aquatic plants are a rich source of health-beneficial substances. One of such organisms is the submerged macrophyte Ceratophyllum demersum, which has not been sufficiently studied in this aspect so far. In this work, we have studied environm
Externí odkaz:
https://doaj.org/article/44a6e123d18843ee9dfc344be9bad969
Autor:
Natalia Nowacka-Jechalke, Sebastian Kanak, Marcin Moczulski, Aleksandra Martyna, Konrad Kubiński, Maciej Masłyk, Nikola Szpakowska, Zbigniew Kaczyński, Renata Nowak, Marta Olech
Publikováno v:
Applied Sciences, Vol 13, Iss 6, p 3853 (2023)
Armillaria mellea is a commonly harvested and consumed mushroom in Poland. Several activities of polysaccharides from this species have already been reported. However, polysaccharides from A. mellea growing in the wild in Poland have not yet been inv
Externí odkaz:
https://doaj.org/article/bc233cb16e2441e38f0a3fbf3268d5ea
Autor:
Konrad Kubiński, Kamila Górka, Monika Janeczko, Aleksandra Martyna, Mateusz Kwaśnik, Maciej Masłyk, Emil Zięba, Joanna Kowalczuk, Piotr Kuśtrowski, Mariusz Borkowski, Anna Boguszewska-Czubara, Agnieszka Klimeczek, Oleg M. Demchuk
Publikováno v:
Molecules, Vol 28, Iss 3, p 1194 (2023)
A new type of silver nanoparticles (AgNPs) was prepared and comprehensively studied. Scanning electron microscopy (SEM) and dynamic light scattering (DLS) analyses indicated that 24 nm AgNPs with narrow size distribution were obtained while Z-potenti
Externí odkaz:
https://doaj.org/article/cb2a5969765641769e59d323e1ae6ff8