Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Maciej Florczyk"'
Autor:
Maciej Florczyk, Agnieszka Cydzik-Kwiatkowska, Aleksandra Ziembinska-Buczynska, Slawomir Ciesielski
Publikováno v:
Applied Sciences, Vol 12, Iss 19, p 9797 (2022)
Direct DNA analysis is the most widely used approach for microorganism characterization in natural and built environments; therefore, reliable and effective methods of nucleic acid extraction for samples from particular types of environments are need
Externí odkaz:
https://doaj.org/article/0286045040e94cdf8a64d272daf20a5a
Autor:
Marta Cegłowska, Patrycja Kwiecień, Karolina Szubert, Paweł Brzuzan, Maciej Florczyk, Christine Edwards, Alicja Kosakowska, Hanna Mazur-Marzec
Publikováno v:
Marine Drugs, Vol 20, Iss 2, p 93 (2022)
Aeruginosamides (AEGs) are classified as cyanobactins, ribosomally synthesized peptides with post-translational modifications. They have been identified in cyanobacteria of genera Microcystis, Oscillatoria, and Limnoraphis. In this work, the new data
Externí odkaz:
https://doaj.org/article/43ea483a75ca4831942defe768915caf
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158899 (2016)
Molecular analyses show that challenging fish with microcystin-LR (MC-LR) causes perturbations of microRNA (miRNA) signaling. However, the significance and scope of these alterations is currently unknown. To address this issue, we studied miRNA gene
Externí odkaz:
https://doaj.org/article/4f4056add2f1424fa480002d7fc6a556
Autor:
Piotr Gomułka, Michał Wesołowski, Paweł Brzuzan, Bogdan Lewczuk, Maciej Florczyk, Maciej Woźny, Stefan Dobosz, Paulina Budzińska
Publikováno v:
Experimental Biology and Medicine. 244:52-63
Here, we provide the first report of an efficient method of in vivo delivery of MiRNA92b-3p mimic by intraperitoneal injection to whitefish, a Teleost fish. Juvenile whitefish were exposed to synthetic MiR92b-3p suspended in Invivofectamine 3.0 trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580bb2af5ea92a2dfbe5b896ebbf599a
https://doi.org/10.1177/1535370218824573
https://doi.org/10.1177/1535370218824573
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 941, p 941 (2021)
Volume 22
Issue 2
International Journal of Molecular Sciences, Vol 22, Iss 941, p 941 (2021)
Volume 22
Issue 2
Microcystin-LR (MC-LR) is a potent hepatotoxin for which a substantial gap in knowledge persists regarding the underlying molecular mechanisms of liver toxicity and injury. Although long non-coding RNAs (lncRNAs) have been extensively studied in mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6d9303e99830a17ddb668f4059a152
https://doi.org/10.21203/rs.3.rs-62335/v1
https://doi.org/10.21203/rs.3.rs-62335/v1
Publikováno v:
Neurotoxicity Research
Microcystin-LR (MC-LR) is a potent hepatotoxin that has also been pointed out of causing neurotoxicity, but the exact mechanisms of action still remain ambiguous and need to be elucidated. Data from studies on mammals show that pathology of astrocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af36a32944189531461d38aff3d10eae
https://doi.org/10.1007/s12640-018-9920-4
https://doi.org/10.1007/s12640-018-9920-4
Publikováno v:
Environmental Biotechnology. 14:1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54bc005fed00070bc40aea38fc99211d
https://doi.org/10.14799/ebms301
https://doi.org/10.14799/ebms301
Autor:
Bogdan Lewczuk, Alicja Łakomiak, Natalia Ziółkowska, Maciej Woźny, Maciej Florczyk, Paweł Brzuzan, Stefan Dobosz, Piotr Gomułka
Publikováno v:
Toxicology and Applied Pharmacology. 313:68-87
To date, there has been no systematic approach comprehensively describing the sequence of pathological changes in fish during prolonged exposure to microcystin-LR (MC-LR). Towards this aim, juvenile whitefish individuals received an intraperitoneal i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364ff74ba7252df937f37b1dacc57d84
https://doi.org/10.1016/j.taap.2016.10.014
https://doi.org/10.1016/j.taap.2016.10.014
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 193:47-56
Studies on mammals have demonstrated that the expression of miR-34a is associated with process of apoptosis in many cell types, by lowering expression of the anti-apoptotic protein Bcl-2. Despite the role of miR-34a, there is no data about the miR-34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1d643acc5c31d164c1b3f66b390440
https://doi.org/10.1016/j.cbpb.2015.12.005
https://doi.org/10.1016/j.cbpb.2015.12.005
Autor:
Hanna Mazur-Marzec, Robert Konkel, Maciej Woźny, Filip Stefaniak, Anna Fidor, Paweł Brzuzan, Maciej Florczyk
Publikováno v:
Toxicology in Vitro. 68:104951
We developed a cell sensor that detects the liver cancer-specific microRNA MIR92b-3p, involved in hepatocellular carcinoma development and hepatitis C virus infection. To validate our small-molecule screen that employs a Huh7 human hepatoma cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1133b6cb9cea9b5d29df6546d35693
https://doi.org/10.1016/j.tiv.2020.104951
https://doi.org/10.1016/j.tiv.2020.104951