Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Maciej Dawidowski"'
Autor:
Marzenna Klimaszewska, Sabina Górska, Grzegorz Łapienis, Beata Kaleta, Sandra Górska, Marta Kaszowska, Maciej Dawidowski, Andrzej Gamian, Radoslaw Zagożdżon, Andrzej Górski, Jadwiga Turło
Publikováno v:
Molecules, Vol 26, Iss 17, p 5404 (2021)
We previously described the biosynthesis, isolation, and immunosuppressive activity of the selenium-containing polysaccharide fraction isolated from the mycelial culture of Lentinula edodes. Structural studies have shown that the fraction was a prote
Externí odkaz:
https://doaj.org/article/698e084141b94e06bb83f9d135c4d558
Autor:
Agata Barzowska, Barbara Pucelik, Katarzyna Pustelny, Alex Matsuda, Alicja Martyniak, Jacek Stępniewski, Anna Maksymiuk, Maciej Dawidowski, Ulli Rothweiler, Józef Dulak, Grzegorz Dubin, Anna Czarna
Publikováno v:
Cells, Vol 10, Iss 9, p 2263 (2021)
The rising prevalence of diabetes is threatening global health. It is known not only for the occurrence of severe complications but also for the SARS-Cov-2 pandemic, which shows that it exacerbates susceptibility to infections. Current therapies focu
Externí odkaz:
https://doaj.org/article/57e400e4727d4c7ea312dfee0248f600
Autor:
Vishal C. Kalel, Leonidas Emmanouilidis, Maciej Dawidowski, Wolfgang Schliebs, Michael Sattler, Grzegorz M. Popowicz, Ralf Erdmann
Publikováno v:
Microbial Cell, Vol 4, Iss 7, Pp 229-232 (2017)
Vector-borne trypanosomatid parasite infections in tropical and sub-tropical countries constitute a major threat to humans and livestock. Trypanosoma brucei parasites are transmitted by tsetse fly and lead to African sleeping sickness in humans and N
Externí odkaz:
https://doaj.org/article/e88678ff3f46427197d710810053753b
Publikováno v:
Molecules, Vol 19, Iss 10, Pp 15955-15981 (2014)
A series of novel stereochemically pure derivatives of the investigative broad-spectrum anticonvulsant ADD408003 was designed and synthesized. Five-center four-component (U-5C-4CR) and four-center three-component (U-4C-3CR) variants of Ugi reaction w
Externí odkaz:
https://doaj.org/article/53c5a75cbfc848648c59c52e36a43f46
Autor:
Valeria Napolitano, Piotr Mróz, Monika Marciniak, Vishal C. Kalel, Charlotte A. Softley, Julian D. Janna Olmos, Bettina G. Tippler, Kenji Schorpp, Sarah Rioton, Tony Fröhlich, Oliver Plettenburg, Kamyar Hadian, Ralf Erdmann, Michael Sattler, Grzegorz M. Popowicz, Maciej Dawidowski, Grzegorz Dubin
Publikováno v:
Eur. J. Med. Chem. 243:114778 (2022)
Trypanosomiases are neglected tropical diseases caused by Trypanosoma (sub)species. Available treatments are limited and have considerable adverse effects and questionable efficacy in the chronic stage of the disease, urgently calling for the identif
Autor:
Ekaterina L. Ratkova, Igor V. Tetko, Michael Sattler, Grzegorz Dubin, Valeria Napolitano, Roberto Fino, Maciej Dawidowski, Grzegorz M. Popowicz, Michael Sebastian Ostertag
Publikováno v:
Chem. Commun. 56, 4360-4363 (2020)
Chemical Communications
Chemical Communications
We show that a water envelope network plays a critical role in protein-protein interactions (PPI). The potency of a PPI inhibitor is modulated by orders of magnitude on manipulation of the solvent envelope alone. The structure-activity relationship o
Autor:
Alex Matsuda, Grzegorz Dubin, Alicja Martyniak, Barbara Pucelik, Jacek Stępniewski, Anna Z. Czarna, Katarzyna Pustelny, Maciej Dawidowski, Jozef Dulak, Ulli Rothweiler, Agata Barzowska, Anna Maksymiuk
Publikováno v:
Cells
Volume 10
Issue 9
Cells, Vol 10, Iss 2263, p 2263 (2021)
Volume 10
Issue 9
Cells, Vol 10, Iss 2263, p 2263 (2021)
The rising prevalence of diabetes is threatening global health. It is known not only for the occurrence of severe complications but also for the SARS-Cov-2 pandemic, which shows that it exacerbates susceptibility to infections. Current therapies focu
Autor:
Wolfgang Schliebs, Charlotte A Softley, Valeria Napolitano, Ryan Byrne, Dominik Lenhart, Michael Sattler, Grzegorz M Popowicz, Roberto Fino, Gisbert Schneider, Maciej Dawidowski, Vishal C. Kalel, Ralf Erdmann, Oliver Plettenburg
Publikováno v:
J. Chem. Inf. Model. 61, 5256-5268 (2021)
Journal of Chemical Information and Modeling, 61 (10)
Journal of Chemical Information and Modeling, 61 (10)
African and American trypanosomiases are estimated to affect several million people across the world, with effective treatments distinctly lacking. New, ideally oral, treatments with higher efficacy against these diseases are desperately needed. Pero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e957c50389039d33e3fd89dae22a34a
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63182
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63182
Autor:
Gabriel Nowak, Jadwiga Turło, Monika Marciniak, Martyna Z. Wróbel, Agata Siwek, Anna Maksymiuk, Maciej Dawidowski, Andrzej Chodkowski
A series of novel 4-butyl-arylpiperazine-3-(1H-indol-3-yl)pyrrolidine-2,5-dione derivatives were synthesized and evaluated for their 5-HT$_{1A}$/D2 receptor affinity and serotonin reuptake inhibition. The compounds exhibited high affinity for the 5-H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d501bcbb3f27a79e84956dd26d8484
https://ruj.uj.edu.pl/xmlui/handle/item/257359
https://ruj.uj.edu.pl/xmlui/handle/item/257359
Autor:
Wolfgang Schliebs, Kamyar Hadian, Bettina Tippler, Michael Sattler, Grzegorz M Popowicz, Kenji Schorpp, Marta Kolonko, Vishal C. Kalel, Ralf Erdmann, Igor V. Tetko, Marcel Kaiser, Leonidas Emmanouilidis, Grzegorz Dubin, Valeria Napolitano, Dominik Lenhart, Pascal Mäser, Roberto Fino, Maciej Dawidowski, Michael Sebastian Ostertag, Oliver Plettenburg
Publikováno v:
Journal of Medicinal Chemistry
Trypanosoma protists are pathogens leading to a spectrum of devastating infectious diseases. The range of available chemotherapeutics against Trypanosoma is limited, and the existing therapies are ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb029db8cead4868f7a46fdbf6527d22
https://ruj.uj.edu.pl/xmlui/handle/item/158724
https://ruj.uj.edu.pl/xmlui/handle/item/158724