Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Macias, Alba"'
Akademický článek
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Autor:
Sánchez-Jiménez, Estefanía, Fernández-Gómez, Beatriz, Magan, Esther, Muñoz-Sáez, Emma, Macias, Alba, Martín, María, Piñeiro, David, Hernández-Jiménez, Macarena, Lagares, Alfonso, Ley, Luis, Oreja-Guevara, Celia, Castro, Fernando De
Publikováno v:
In IBRO Neuroscience Reports October 2023 15 Supplement 1:S604-S604
Autor:
Kuki, Naoki, Walmsley, David L., Kanai, Kazuo, Takechi, Sho, Yoshida, Masao, Murakami, Ryo, Takano, Kohei, Tominaga, Yuichi, Takahashi, Mizuki, Ito, Shuichiro, Nakao, Naoki, Angove, Hayley, Baker, Lisa M., Carter, Edward, Dokurno, Pawel, Le Strat, Loic, Macias, Alba T., Molyneaux, Carrie-Anne, Murray, James B., Surgenor, Allan E., Hamada, Tomoaki, Hubbard, Roderick E.
Publikováno v:
MedChemComm; 2023, Vol. 14 Issue: 12 p2731-2737, 7p
Autor:
Yuya Ogata, Harumi Kanazawa, Macias Alba, Norikazu Ohtake, Allan E. Surgenor, Iichiro Takata, Hajime Takashima, Walmsley David, Kiyoko Fujita, Hayley Angove, Kunihiko Iwamoto, Masashi Mima, Hiroyuki Sugiyama, Fumihito Ushiyama, Junya Yamagishi, Yousuke Yamada, Alan P. Robertson, Kosuke Hitaka, Koichiro Nakano, Hayato Watanabe, Atsushi Okada, Yohei Matsuda, Roderick E. Hubbard, Nozomi Tanaka-Yamamoto, Toru Yamaguchi-Sasaki, Risa Kurimoto-Tsuruta, Lisa Baker, Akihiro Tanaka, R. Harris
Publikováno v:
Journal of medicinal chemistry. 63(23)
UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) is a zinc metalloenzyme that catalyzes the first committed step in the biosynthesis of Lipid A, an essential component of the cell envelope of Gram-negative bacteria. The most advanced, disclosed Lp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019ee8a95fea26f38a355f0054fb803d
https://pubmed.ncbi.nlm.nih.gov/33210531
https://pubmed.ncbi.nlm.nih.gov/33210531
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Macias, Alba T, Hernandez, R.Jason, Mehta, Ashok K, MacKerell, Alexander D, Jr., Ticku, Maharaj K, Coop, Andrew
Publikováno v:
In Bioorganic & Medicinal Chemistry 2004 12(7):1643-1647
Autor:
Stephen Stokes, Patrick C. Mahon, Alan D. Robertson, Jalanie D’Alessandro, Paul Webb, Charles Parry, Lisa Baker, Natalia Matassova, Nicholas G. M. Davies, Sean McKenna, Andrew Massey, Rachel Parsons, Yikang Wang, Macias Alba, Paul Brough, Ben Davis, Michael Wood, Simon Bedford, Jonathan D. Moore, Christopher J. Northfield, Loic le Strat, Stephen D. Roughley, Daniel Maddox, Seema Chavda, James Brooke Murray, Allan E. Surgenor, Johannes W. G. Meissner, Terry Shaw, Heather Simmonite, Stefaniak Emma Jayne, Victoria Chell, Neil Whitehead, Kirsten Brown
Publikováno v:
Journal of medicinal chemistry. 60(6)
Libraries of nonpurified resorcinol amide derivatives were screened by surface plasmon resonance (SPR) to determine the binding dissociation constant (off-rate, kd) for compounds binding to the pyruvate dehydrogenase kinase (PDHK) enzyme. Parallel of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5f231f5660155f00b4666296b0e799
https://pubmed.ncbi.nlm.nih.gov/28199108
https://pubmed.ncbi.nlm.nih.gov/28199108
Autor:
Anna Staniszewska, Lisa Baker, Jonathan D. Moore, James Murray, Patrick C. Mahon, Terence Shaw, Paul Brough, Alan Surgenor, Michael Wood, Ben Davis, Jalanie D’Alessandro, Natalia Matassova, Macias Alba
Publikováno v:
Scopus-Elsevier
Oncotarget
Oncotarget
Pyruvate dehydrogenase kinase (PDK) is a pivotal enzyme in cellular energy metabolism that has previously been implicated in cancer through both RNAi based studies and clinical correlations with poor prognosis in several cancer types. Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a89876a6f42b6b5319184f7f142c89
https://doi.org/10.18632/oncotarget.2656
https://doi.org/10.18632/oncotarget.2656
Autor:
Sean McKenna, Andrew Massey, Lisa Baker, K Benwell, Heather Simmonite, Teresa Brooks, Michael Wood, Stephen Stokes, Nicolas Foloppe, Andrea Fiumana, Paul Webb, Stefaniak Emma Jayne, Christopher J. Northfield, Macias Alba, Zoe Daniels, Daniel Maddox, Helen Browne, Joanne Wayne, Christopher John Graham, Stuart C. Ray
Publikováno v:
Molecular Cancer Therapeutics. 17:B163-B163
On sustaining damage to their DNA, cells employ a sophisticated mechanism of detection and repair, termed the DNA damage response (DDR). As a critical component of the DDR and G2/M checkpoint, Chk1 kinase represents an attractive target for cancer th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4ad7ce30c29670a74658952948678e4
https://doi.org/10.1158/1535-7163.targ-17-b163
https://doi.org/10.1158/1535-7163.targ-17-b163