Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Machteld J van Amerongen"'
Autor:
Salvador Cazorla-Vázquez, Arndt Hartmann, Felix B. Engel, Machteld J. van Amerongen, Thomas Brabletz, Markus Eckstein, Thomas Braun, Marc P. Stemmler, Gentian Musa
Publikováno v:
Annals of the New York Academy of Sciences. 1456:96-108
GPR126 (ADGRG6) is an adhesion G protein-coupled receptor that plays an important role in a variety of tissues/organs, such as heart, sciatic nerve, cartilage, and ear. Moreover, GPR126 (ADGRG6) mutations are associated with human diseases, like adol
Autor:
Florian Diehl, Mark A Brown, Machteld J van Amerongen, Tatyana Novoyatleva, Astrid Wietelmann, June Harriss, Fulvia Ferrazzi, Thomas Böttger, Richard P Harvey, Philip W Tucker, Felix B Engel
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9748 (2010)
Chromatin modifying enzymes play a critical role in cardiac differentiation. Previously, it has been shown that the targeted deletion of the histone methyltransferase, Smyd1, the founding member of the SET and MYND domain containing (Smyd) family, in
Externí odkaz:
https://doaj.org/article/f8f389f43c3d47fb8b3b93fde593929d
Autor:
Christian Mühlfeld, Subhajit Ghosh, Kelly R. Monk, Felix B. Engel, Amna Sajjad, Amit Mogha, Tatyana Novoyatleva, Chinmoy Patra, Machteld J. van Amerongen, Filomena Ricciardi
Publikováno v:
Proceedings of the National Academy of Sciences. 110:16898-16903
Significance Adhesion G protein-coupled receptors (GPCRs) are expressed in many developing organs, immune cells, and cancer cells, suggesting that they might play an important role in physiological and pathological functions. Compared with their pote
Autor:
Felix B. Engel, Benno Jungblut, Tatyana Novoyatleva, Christian Mühlfeld, Machteld J. van Amerongen, Chinmoy Patra, Florian Diehl, Fulvia Ferrazzi, Liliana Schaefer
Publikováno v:
Development (Cambridge, England)
The extracellular matrix is crucial for organogenesis. It is a complex and dynamic component that regulates cell behavior by modulating the activity, bioavailability and presentation of growth factors to cell surface receptors. Here, we determined th
Publikováno v:
Cardiovascular Research. 86:92-102
Aims Although the fundamental role of the E2F transcription factor family in cell proliferation is well established, the specific function of E2F4 is unclear. On the basis of findings from cell culture experiments, E2F4 is generally considered as an
Autor:
Chinmoy Patra, Florian Diehl, Tatyana Novoyatleva, Riccardo Bellazzi, Machteld J. van Amerongen, Fulvia Ferrazzi, Felix B. Engel
Publikováno v:
Cardiovascular Research. 85:681-690
Aims Proliferation of mammalian cardiomyocytes stops during the first weeks after birth, preventing the heart from regenerating after injury. Recently, several studies have indicated that induction of cardiomyocyte proliferation can be utilized to re
Publikováno v:
Journal of Cellular and Molecular Medicine
The human heart does not regenerate. Instead, following injury, human hearts scar. The loss of contractile tissue contributes significantly to morbidity and mortality. In contrast to humans, zebrafish and newts faithfully regenerate their hearts. Int
Autor:
Martin C. Harmsen, Arjen H. Petersen, Machteld J. van Amerongen, Eliane R. Popa, Marja J. A. van Luyn
Publikováno v:
Cardiovascular Pathology, 17(1), 23-31. ELSEVIER SCIENCE INC
Introduction: Although traditionally adult cardiomyocytes are thought to be unable to divide, recent observations provide evidence for cardiomyocyte proliferation after myocardial injury. Myocardial cryoinjury has been shown to be followed by neovasc
Autor:
Marja J. A. van Luyn, Nico van Rooijen, Martin C. Harmsen, Machteld J. van Amerongen, Arjen H. Petersen
Publikováno v:
American Journal of Pathology, 170(3), 818-829. ELSEVIER SCIENCE INC
Macrophages have been suggested to be beneficial for myocardial wound healing. We investigated the role of macrophages in myocardial wound healing by inhibition of macrophage infiltration after myocardial injury. We used a murine cryoinjury model to
Autor:
Martin C. Harmsen, Pieter C. de Feijter, Marja J. A. van Luyn, Daniel T. Luttikhuizen, Machteld J. van Amerongen, Arjen H. Petersen
Publikováno v:
Biomaterials, 27(34), 5763-5770. ELSEVIER SCI LTD
The foreign body reaction (FBR) differs between subcutaneously and supra-epicardially implanted materials. We hypothesize that this is a result of differences in cytokine, chemokine and matrix metalloproteinase (MNIP) dynamics. Therefore we applied c