Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Machiko Atsuta"'
Autor:
Yoshihiro Hayakawa, Machiko Atsuta, Kimio Kobayashi, Kazuyoshi Takeda, Mamoru Ito, Seokmann Hong, Hideo Yagita, Luc Van Kaer, Ko Okumura
Publikováno v:
International Immunology. 12:909-914
Conventional T cells, NK cells and NKT cells have been implicated in the anti-tumor activities induced by IL-12. Here we show that IL-12-induced immune responses are partially impaired in T and NKT cell-deficient RAG-2(-/-) mice, and in NKT cell-defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c5fd209f92dbca7f322fe12b922b15
https://doi.org/10.1093/intimm/12.6.909
https://doi.org/10.1093/intimm/12.6.909
Publikováno v:
Biochemical and Biophysical Research Communications. 251:131-136
OX40 (CD134) is a member of the tumor necrosis factor (TNF) receptor superfamily first identified as a rat T cell activation marker. In the present study, we identified the rat ligand for OX40 (OX40L) by molecular cloning. Rat OX40L cDNA was cloned f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee33ee4a77e62d02db7f1f221bf21c47
https://doi.org/10.1006/bbrc.1998.9376
https://doi.org/10.1006/bbrc.1998.9376
Autor:
Machiko Atsuta, Masahisa Shindo, Hiroyasu Nakano, Chikao Morimoto, Hisaya Akiba, Carl F. Ware, Nikolai Malinin, David Wallach, Hideo Yagita, Ko Okumura, Shigeyuki Nishinaka, Tetsuji Kobata
Publikováno v:
Journal of Biological Chemistry. 273:13353-13358
CD27 is a member of the tumor necrosis factor (TNF) receptor superfamily and is expressed on T, B, and NK cells. The signal via CD27 plays pivotal roles in T-T and T-B cell interactions. Here we demonstrate that overexpression of CD27 activates NF-ka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6979e018454b61af8417493fe866fc
https://doi.org/10.1074/jbc.273.21.13353
https://doi.org/10.1074/jbc.273.21.13353
Publikováno v:
Biochemical and biophysical research communications. 270(3)
OX40 (CD134) is a member of the tumor necrosis factor (TNF) receptor superfamily first identified as a rat T cell activation marker. We previously identified the rat ligand for OX40 (OX40L) by molecular cloning. In the present study, we newly generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91dd8558e3dc69915997ebdb25bdad46
https://pubmed.ncbi.nlm.nih.gov/10772947
https://pubmed.ncbi.nlm.nih.gov/10772947
Autor:
Hideo Yagita, Hisaya Akiba, Machiko Atsuta, Tetsuji Kobata, Mamoru Ito, Kazuyoshi Takeda, Hideo Oshima, Kimio Kobayashi, Ko Okumura, Yoshihiro Hayakawa
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 164(4)
CD27, a member of the TNF receptor superfamily, has been implicated in T cell activation, T cell development, and T cell-dependent Ab production by B cells. In the present study we examined the expression and function of CD27 on murine NK cells. Muri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b04c43794b5e7f09e1f5d6589fc7af0
https://pubmed.ncbi.nlm.nih.gov/10657619
https://pubmed.ncbi.nlm.nih.gov/10657619
Autor:
Hironori Matsuda, Ko Okumura, Toshiro Futagawa, Hisaya Akiba, Kazuyoshi Takeda, Hideo Yagita, Chiyoko Nohara, Yasushi Miyahira, Takashi Aoki, Machiko Atsuta
Publikováno v:
The Journal of Experimental Medicine
Infection of inbred mouse strains with Leishmania major is a well characterized model for analysis of T helper (Th)1 and Th2 cell development in vivo. In this study, to address the role of costimulatory molecules CD27, CD30, 4-1BB, and OX40, which be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b575b49673bfd24c90f677ea00b88ae3
https://pubmed.ncbi.nlm.nih.gov/10637281
https://pubmed.ncbi.nlm.nih.gov/10637281
Autor:
Hisaya Akiba, Hideo Oshima, Kazuyoshi Takeda, Machiko Atsuta, Hiroyasu Nakano, Atsuo Nakajima, Chiyoko Nohara, Hideo Yagita, Ko Okumura
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(12)
OX40 and its ligand (OX40L) have been implicated in T cell-dependent humoral immune responses. To further characterize the role of OX40/OX40L in T-B cell interaction, we newly generated an anti-mouse OX40L mAb (RM134L) that can inhibit the costimulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d7d74b044e55136afb0169c90ec7e0
https://pubmed.ncbi.nlm.nih.gov/10358148
https://pubmed.ncbi.nlm.nih.gov/10358148
Autor:
Hideo Yagita, Machiko Atsuta, Kimio Kobayashi, Yoshihiro Hayakawa, Ko Okumura, Osamu Shimozato, Tomohiro Kodama, Mamoru Ito, Kazuyoshi Takeda
Publikováno v:
European journal of immunology. 29(4)
IL-12 exerts a potent anti-tumor effect, which is possibly mediated by multiple mechanisms including activation of NK and NKT cells, induction of cytotoxic T lymphocytes, and inhibition of angiogenesis. In the present study, we characterized the cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f828d13d343aab59bb8706e53a9d4e14
https://pubmed.ncbi.nlm.nih.gov/10229107
https://pubmed.ncbi.nlm.nih.gov/10229107