Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Machhindra Gund"'
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 11, Pp o2720-o2720 (2009)
In the title compound, C11H8ClNO2, the quinoline fused-ring system is almost planar (r.m.s. deviation = 0.020 Å). The formyl group is slightly bent out of the quinoline plane [deviation of the O atom = 0.371 (2) Å].
Externí odkaz:
https://doaj.org/article/67a63dbc7f534f519e0cf8bc7a318e78
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 11, Pp o2723-o2723 (2009)
The quinoline fused-ring system of the title compound, C11H8ClNO2, is planar (r.m.s. deviation = 0.0095 Å); the formyl group is slightly bent out of this plane [C—C—C—O torsion angles = −2.4 (3) and 175.9 (2)°].
Externí odkaz:
https://doaj.org/article/98bc508924984489a9b2914830466067
Publikováno v:
Canadian Journal of Chemistry. 96:311-327
We report formal intramolecular (4+1)-cycloadditions of dialkoxycarbenes used in the synthesis of the daucane-type sesquiterpene carotol. We found a chiral dialkoxycarbene capable of diastereoselective formation of a key oxabicyclo[3.3.0]octene adduc
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1269-1273
Multi-drug resistant tuberculosis (MDR-TB) is emerging as a serious global health problem, which has been elevated through co-infection involving HIV and MDR-Mtb. The discovery of new compounds with anti-MDR TB efficacy and favorable metabolism profi
Publikováno v:
European Journal of Pharmaceutical Sciences. 49:227-232
A series of nicotinic acid conjugates with non-steroidal anti-inflammatory drugs (NSAID’s) have been effectively synthesized using TBTU in high yield and purity. All the synthesized conjugates were evaluated for their in vitro anti-inflammatory act
Publikováno v:
Organic letters. 18(17)
Dialkoxycarbenes are more reactive than NHCs and participate in many reactions including a formal (4 + 1) cycloaddition with electron-deficient dienes. We have learned to control the relative stereochemistry of the newly created chiral carbons in thi
Autor:
Jong Sung Jin, S. Mohana Roopan, A. Sudheer Kumar, Fazlur-Rahman Nawaz Khan, Machhindra Gund, Rajesh Kumar
Publikováno v:
Research on Chemical Intermediates. 38:1111-1118
An efficient and regioselective O-alkylation of amides with a variety of electrophiles in the presence of silver nanoparticles is reported as part of our recent research on building blocks for synthesis of natural products. The nano-silver catalyst i
Publikováno v:
Synthetic Communications. 36:1051-1056
A simple route to 7‐formyl‐indole (5) is described in which appropriately functionalized o‐nitrotoluenes (1) are converted to 7‐hydroxymethyl‐indole (4) using the Batcho–Leimgruber process. Condensation of 3‐methyl‐2‐nitrobenzyl alc
Autor:
Javed Sheikh, Aslam Burhan, Parikshit Gaikwad, Mohan Patil, Santhosh Goud Tipparam, Mini Dhiman, Machhindra Gund, Dattatraya C. Desai, Gajanan Thakre, Ankur Sharma, Namdev Borhade, Somesh Sharma, Apparao Satyam, Kumar V.S. Nemmani
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(24)
Nitric oxide-releasing non-steroidal anti-inflammatory drugs (NO-NSAIDs) are gaining attention as potentially gastric-sparing NSAIDs. Herein, we report a novel class of ‘1-(nitrooxy)ethyl ester’ group-containing NSAIDS as efficient NO releasing
Autor:
Jayesh Mudgal, Somesh Sharma, Milan Chandra Dutta, Asif R. Pathan, Jagannath Janardhan Deshattiwar, Shubhada Deshpande, Somnath Halder, Parikshit Gaikwad, Gajanan Thakre, Apparao Satyam, Ankur Sharma, Venu Pamidiboina, Nauzer P. Dubash, Santhosh Goud Tipparam, Aslam Burhan, Machhindra Gund, Dattatraya C. Desai, Mini Dhiman, Kumar V.S. Nemmani, Arun Kumar Jain, Subrayan Palanisamy Senthilkumar, Manoj Karwa, Nitin J. Deshmukh, Sunil Vasantrao Mali, Namdev Borhade
Publikováno v:
Chemicalpharmaceutical bulletin. 60(4)
In continuation of our efforts to discover novel nitric oxide-releasing non-steroidal anti-inflammatory drugs (NO-NSAIDs) as potentially "Safe NSAIDs," we report herein the design, synthesis and evaluation of 21 new NO-NSAIDs of commonly used NSAIDs