Second-Shell Amino Acid R266 Helps Determine N -Succinylamino Acid Racemase Reaction Specificity in Promiscuous N -Succinylamino Acid Racemase/ o -Succinylbenzoate Synthase Enzymes.

Autor: Truong DP; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, Texas 77843-2128, United States., Rousseau S; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, Texas 77843-2128, United States., Machala BW; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, Texas 77843-2128, United States., Huddleston JP; Department of Chemistry, Texas A&M University, 3255 TAMU, College Station, Texas 77843-3255, United States., Zhu M; Baylor Synthesis and Drug-Lead Discovery Laboratory, Department of Chemistry and Biochemistry, Baylor University, One Bear Place, Waco, Texas 76798-7348, United States., Hull KG; Baylor Synthesis and Drug-Lead Discovery Laboratory, Department of Chemistry and Biochemistry, Baylor University, One Bear Place, Waco, Texas 76798-7348, United States., Romo D; Baylor Synthesis and Drug-Lead Discovery Laboratory, Department of Chemistry and Biochemistry, Baylor University, One Bear Place, Waco, Texas 76798-7348, United States., Raushel FM; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, Texas 77843-2128, United States.; Department of Chemistry, Texas A&M University, 3255 TAMU, College Station, Texas 77843-3255, United States., Sacchettini JC; Department of Chemistry, Texas A&M University, 3255 TAMU, College Station, Texas 77843-3255, United States., Glasner ME; Department of Biochemistry and Biophysics, Texas A&M University, 2128 TAMU, College Station, Texas 77843-2128, United States.

Publikováno v: Biochemistry [Biochemistry] 2021 Dec 21; Vol. 60 (50), pp. 3829-3840. Date of Electronic Publication: 2021 Nov 30.