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The single-cell transcriptome of mTECs and CD4 ⁺ thymocytes under adhesion revealed heterogeneity of mTECs and a network controlled by Aire and lncRNAs.

Autor: Monteiro CJ; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Duarte MJ; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Machado MCV; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Mascarenhas RS; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Palma PVB; Blood Center of Ribeirão Preto, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., García HDM; Institute of Biology, Campinas State University (UNICAMP), Campinas, SP, Brazil., Nakaya HI; Research Institute, Albert Einstein Israeli Hospital, São Paulo, SP, Brazil.; Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Cunha TM; Center for Research in Inflammatory Diseases, Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Donadi EA; Department of Medicine, Division of Clinical Immunology, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil., Passos GA; Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.; Department of Basic and Oral Biology, Ribeirão Preto School of Dentistry, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.; Center for Cell-Based Therapy in Dentistry, Ribeirão Preto School of Dentistry, University of São Paulo (USP), Ribeirão Preto, SP, Brazil.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Aug 26; Vol. 15, pp. 1376655. Date of Electronic Publication: 2024 Aug 26 (Print Publication: 2024).