Intraoperative Oxygen Treatment, Oxidative Stress, and Organ Injury Following Cardiac Surgery: A Randomized Clinical Trial.

Autor: Lopez MG; Department of Anesthesiology, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Shotwell MS; Department of Biostatistics, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Hennessy C; Department of Biostatistics, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Pretorius M; Department of Anesthesiology, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., McIlroy DR; Department of Anesthesiology, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Kimlinger MJ; Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Mace EH; Department of Surgery, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Absi T; Department of Cardiac Surgery, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Shah AS; Department of Cardiac Surgery, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Brown NJ; Department of Medicine, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Billings FT 4th; Department of Anesthesiology, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee.; Department of Medicine, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee.

Publikováno v: JAMA surgery [JAMA Surg] 2024 Oct 01; Vol. 159 (10), pp. 1106-1116.

Vascular imaging immediately after tourniquet removal does not increase vasospasm risk.

Autor: Mace EH; Vanderbilt University Medical Center, Department of General Surgery, Nashville, Tennessee, Medical Center North, D-5203, Suite CCC-4312, 1161 21st Avenue South, Nashville, TN 37232-2730, USA., Maiga AW; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA. Electronic address: amelia.w.maiga@vumc.org., Beyene RT; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Smith MC; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Streams JR; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Peetz AB; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Dennis BM; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Guillamondegui OD; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Gondek SP; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA.

Publikováno v: Injury [Injury] 2024 Jan; Vol. 55 (1), pp. 110974. Date of Electronic Publication: 2023 Aug 02.

Targeting Soluble Guanylyl Cyclase during Ischemia and Reperfusion.

Autor: Mace EH; Department of Surgery, Vanderbilt University Medical Center, Medical Center North, Suite CCC-4312, 1161 21st Avenue South, Nashville, TN 37232-2730, USA., Kimlinger MJ; Vanderbilt University School of Medicine, 428 Eskind Family Biomedical Library and Learning Center, Nashville, TN 37240-0002, USA., Billings FT 4th; Department of Anesthesiology, Division of Critical Care Medicine, Vanderbilt University Medical Center, Medical Arts Building, Suite 422, 1211 21st Avenue South, Nashville, TN 37212-1750, USA., Lopez MG; Department of Anesthesiology, Division of Critical Care Medicine, Vanderbilt University Medical Center, Medical Arts Building, Suite 422, 1211 21st Avenue South, Nashville, TN 37212-1750, USA.

Publikováno v: Cells [Cells] 2023 Jul 21; Vol. 12 (14). Date of Electronic Publication: 2023 Jul 21.

Impact of Inhaled Oxygen on Reactive Oxygen Species Production and Oxidative Damage during Spontaneous Ventilation in a Murine Model of Acute Renal Ischemia and Reperfusion.

Autor: Kimlinger MJ; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Mace EH; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Harris RC; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Zhang MZ; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Barajas MB; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Hernandez A; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Billings FT 4th; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN.

Publikováno v: Medical research archives [Med Res Arch] 2021 Oct; Vol. 9 (10). Date of Electronic Publication: 2021 Oct 28.

Endothelial nitric oxide synthase modulates Toll-like receptor 4-mediated IL-6 production and permeability via nitric oxide-independent signaling.

Autor: Stark RJ; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Koch SR; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Choi H; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Mace EH; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Dikalov SI; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA; and., Sherwood ER; Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Lamb FS; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2018 Feb; Vol. 32 (2), pp. 945-956. Date of Electronic Publication: 2018 Jan 03.