Intraoperative Oxygen Treatment, Oxidative Stress, and Organ Injury Following Cardiac Surgery: A Randomized Clinical Trial.

Autor: Lopez MG; Department of Anesthesiology, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Shotwell MS; Department of Biostatistics, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Hennessy C; Department of Biostatistics, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Pretorius M; Department of Anesthesiology, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., McIlroy DR; Department of Anesthesiology, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Kimlinger MJ; Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Mace EH; Department of Surgery, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Absi T; Department of Cardiac Surgery, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Shah AS; Department of Cardiac Surgery, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Brown NJ; Department of Medicine, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee., Billings FT 4th; Department of Anesthesiology, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee.; Department of Medicine, Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee.

Publikováno v: JAMA surgery [JAMA Surg] 2024 Oct 01; Vol. 159 (10), pp. 1106-1116.

Vascular imaging immediately after tourniquet removal does not increase vasospasm risk.

Autor: Mace EH; Vanderbilt University Medical Center, Department of General Surgery, Nashville, Tennessee, Medical Center North, D-5203, Suite CCC-4312, 1161 21st Avenue South, Nashville, TN 37232-2730, USA., Maiga AW; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA. Electronic address: amelia.w.maiga@vumc.org., Beyene RT; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Smith MC; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Streams JR; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Peetz AB; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Dennis BM; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Guillamondegui OD; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA., Gondek SP; Vanderbilt University Medical Center, Division of Acute Care Surgery, Nashville, Tennessee, Medical Arts Building, Suite 404, 1211 21st Avenue South, Nashville Tennessee 37212-1750, USA.

Publikováno v: Injury [Injury] 2024 Jan; Vol. 55 (1), pp. 110974. Date of Electronic Publication: 2023 Aug 02.

SOLUBLE GUANYLYL CYCLASE ACTIVATION RESCUES HYPEROXIA-INDUCED DYSFUNCTION OF VASCULAR RELAXATION.

Autor: Mace EH; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN., Kimlinger MJ; School of Medicine, Vanderbilt University, Nashville, Tennessee., No TJ; College of Arts and Sciences, Vanderbilt University, Nashville, Tennessee., Dikalov SI; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Hennessy C; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee., Shotwell MS; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee., Billings FT 4th; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee., Lopez MG; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee.

Publikováno v: Shock (Augusta, Ga.) [Shock] 2022 Oct 01; Vol. 58 (4), pp. 280-286. Date of Electronic Publication: 2022 Aug 16.

Impact of Inhaled Oxygen on Reactive Oxygen Species Production and Oxidative Damage during Spontaneous Ventilation in a Murine Model of Acute Renal Ischemia and Reperfusion.

Autor: Kimlinger MJ; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Mace EH; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Harris RC; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Zhang MZ; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Barajas MB; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Hernandez A; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN., Billings FT 4th; Vanderbilt University School of Medicine (MJK), the Department Surgery (EM), the Department of Medicine (RCH, MZ), and the Department of Anesthesiology (MBB, AH, FTB), Vanderbilt University Medical Center, Nashville, TN.

Publikováno v: Medical research archives [Med Res Arch] 2021 Oct; Vol. 9 (10). Date of Electronic Publication: 2021 Oct 28.

Toll-like receptor 3-mediated inflammation by p38 is enhanced by endothelial nitric oxide synthase knockdown.

Autor: Koch SR; Department of Pediatrics, Vanderbilt University Medical Center, 2200 Children's Way, 5121 Doctors' Office Tower, Nashville, TN, 37232-9075, USA., Choi H; Department of Pediatrics, Vanderbilt University Medical Center, 2200 Children's Way, 5121 Doctors' Office Tower, Nashville, TN, 37232-9075, USA., Mace EH; Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Stark RJ; Department of Pediatrics, Vanderbilt University Medical Center, 2200 Children's Way, 5121 Doctors' Office Tower, Nashville, TN, 37232-9075, USA. ryan.stark@vumc.org.

Publikováno v: Cell communication and signaling : CCS [Cell Commun Signal] 2019 Apr 15; Vol. 17 (1), pp. 33. Date of Electronic Publication: 2019 Apr 15.