Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Macdonell J. Stanford"'
Autor:
Javier H. Jara, Barış Genç, Macdonell J. Stanford, Peter Pytel, Raymond P. Roos, Sandra Weintraub, M. Marsel Mesulam, Eileen H. Bigio, Richard J. Miller, P. Hande Özdinler
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-20 (2017)
Abstract Background Recent evidence indicates the importance of innate immunity and neuroinflammation with microgliosis in amyotrophic lateral sclerosis (ALS) pathology. The MCP1 (monocyte chemoattractant protein-1) and CCR2 (CC chemokine receptor 2)
Externí odkaz:
https://doaj.org/article/97c3d0e9ad8a4982a0dcf8b1afc51f08
Autor:
Yongling Zhu, Steven H. DeVries, P H Özdinler, Macdonell J. Stanford, William W. Hauswirth, Michael William Tu, Martha C. Bohn, Javier H. Jara
Publikováno v:
Gene Therapy
Direct gene delivery to the neurons of interest, without affecting other neuron populations in the cerebral cortex, represent a challenge owing to the heterogeneity and cellular complexity of the brain. Genetic modulation of corticospinal motor neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e788ed1a3acc8aba99635c788686ce0
https://doi.org/10.1038/gt.2015.112
https://doi.org/10.1038/gt.2015.112
Autor:
Peter Pytel, Sandra Weintraub, Barış Genç, Raymond P. Roos, Richard J. Miller, Javier H. Jara, P. Hande Özdinler, Eileen H. Bigio, M.-Marsel Mesulam, Macdonell J. Stanford
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-20 (2017)
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-20 (2017)
Background Recent evidence indicates the importance of innate immunity and neuroinflammation with microgliosis in amyotrophic lateral sclerosis (ALS) pathology. The MCP1 (monocyte chemoattractant protein-1) and CCR2 (CC chemokine receptor 2) signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce21e20afcb3a0b650cead7016a17ce
https://pubmed.ncbi.nlm.nih.gov/28651542
https://pubmed.ncbi.nlm.nih.gov/28651542
Autor:
Tim Meyer, Pietro Fratta, Macdonell J. Stanford, P. Hande Özdinler, Rachele A. Saccon, David L.H. Bennett, Patrick M. Nolan, Michelle Simon, Ines Heise, Peter I. Joyce, Sarah K. Carter, Linda Greensmith, Michelle Stewart, Silvia Corrochano, Steven J. West, Virginie Bros-Facer, Sebastian Brandner, William Weber, Elizabeth M. C. Fisher, Ning Zhu, Vinaya Phatak, James R. T. Dick, Philip McGoldrick, Saumya Kumar, Tu Vinh Luong, Abraham Acevedo-Arozena
Publikováno v:
Human Molecular Genetics
Transgenic mouse models expressing mutant superoxide dismutase 1 (SOD1) have been critical in furthering our understanding of amyotrophic lateral sclerosis (ALS). However, such models generally overexpress the mutant protein, which may give rise to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab79f270aa4da333d4f728936be6a000
https://doi.org/10.1093/hmg/ddu605
https://doi.org/10.1093/hmg/ddu605
Autor:
Macdonell J. Stanford, P. Hande Özdinler, Mukesh Gautam, Megan C. Schultz, Christine J. DiDonato, Gregory A. Cox, Daniel B. Heller, Jodi L. Klessner, Charles J. Heckman, Marin Manuel, Javier H. Jara, Barış Genç, Gabriella Sekerková
Publikováno v:
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology, Wiley, 2016, 3 (5), pp.331-345. ⟨10.1002/ACN3.298⟩
Annals of Clinical and Translational Neurology, Wiley, 2016, 3 (5), pp.331-345. ⟨10.1002/ACN3.298⟩
Objective The aim of this study was to investigate the role of ubiquitin C-terminal hydrolase-L1 (UCHL1) for motor neuron circuitry and especially in spinal motor neuron (SMN) health, function, and connectivity. Methods Since mutations in UCHL1 gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ccd5277a38937a3b5f002532a9f348
https://hal.archives-ouvertes.fr/hal-02415079
https://hal.archives-ouvertes.fr/hal-02415079
