Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Macarena S. Aloi"'
Autor:
Macarena S. Aloi, Guillermo F. Poblete, John Oldham, Michelle A. Patriquin, David A. Nielsen, Thomas R. Kosten, Ramiro Salas
Publikováno v:
npj Mental Health Research, Vol 2, Iss 1, Pp 1-8 (2023)
Abstract Borderline personality disorder (BPD) is characterized by patterns of unstable affect, unstable interpersonal relationships, and chronic suicidal tendencies. Research on the genetics, epigenetics, and brain function of BPD is lacking. MicroR
Externí odkaz:
https://doaj.org/article/ef3d2517d3b04f0c9e5c6a050e66e4b0
Autor:
Macarena S. Aloi, Katherine E. Prater, Raymond E. A. Sánchez, Asad Beck, Jasmine L. Pathan, Stephanie Davidson, Angela Wilson, C. Dirk Keene, Horacio de la Iglesia, Suman Jayadev, Gwenn A. Garden
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Alzheimer’s Disease (AD) is characterized by the accumulation of extracellular amyloid-β (Aβ) as well as CNS and systemic inflammation. Microglia, the myeloid cells resident in the CNS, use microRNAs to rapidly respond to inflammatory si
Externí odkaz:
https://doaj.org/article/12e50782b5f14fdc92537e1a7d1abe77
Autor:
Katherine E. Prater, Rachel A. Chernoff, Macarena S. Aloi, Jasmine L. Pathan, Jonathan Weinstein, Gwenn A. Garden, Chloe N. Winston, Matthew P. Sadgrove, Stephanie Davidson, Wei Su, Ashley McDonough, Dannielle Zierath
Publikováno v:
J Neurosci
Microglia maintain brain health and play important roles in disease and injury. Despite the known ability of microglia to proliferate, the precise nature of the population or populations capable of generating new microglia in the adult brain remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26da20e71bbf01bb3990278943f539da
https://doi.org/10.1523/jneurosci.1893-20.2021
https://doi.org/10.1523/jneurosci.1893-20.2021
Autor:
Katherine E. Prater, Bryce L. Sopher, Macarena S. Aloi, Suman Jayadev, Gwenn A. Garden, Stephanie Davidson
Publikováno v:
Glia. 69:1736-1748
Microglia are the innate immune cells of the central nervous system that adopt rapid functional changes in response to Damage Associated Molecular Patterns, including aggregated β-Amyloid (Aβ) found in Alzheimer's disease (AD). microRNAs (miRNAs) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::703517c4ed92369f5d1062cd05bef97f
https://doi.org/10.1002/glia.23988
https://doi.org/10.1002/glia.23988
Publikováno v:
Cell reports. 41(8)
Mutations in Kv1.1 (Kcna1) voltage-gated potassium channels in humans and mice generate network hyperexcitability, enhancing aberrant postnatal neurogenesis in the dentate subgranular zone, resulting in epilepsy and hippocampal hypertrophy. While Kcn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcc4250d940c8c014a95daaee00cb52
https://pubmed.ncbi.nlm.nih.gov/36417872
https://pubmed.ncbi.nlm.nih.gov/36417872
Autor:
Macarena S, Aloi, Katherine E, Prater, Bryce, Sopher, Stephanie, Davidson, Suman, Jayadev, Gwenn A, Garden
Publikováno v:
Glia
Microglia are the innate immune cells of the central nervous system that adopt rapid functional changes in response to Damage Associated Molecular Patterns, including aggregated β-Amyloid (Aβ) found in Alzheimer's disease (AD). microRNAs (miRNAs) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed7f552406a6a8da3d8d6205e38c2319
https://pubmed.ncbi.nlm.nih.gov/33694209
https://pubmed.ncbi.nlm.nih.gov/33694209
Autor:
Amanda Case, James Gillespie, John Kang, Stephanie Hopkins, David B. Wang, Macarena S. Aloi, Guy L. Odom, Wei Su, Gwenn A. Garden, Jeffrey S. Chamberlain, Bryce L. Sopher
Publikováno v:
Journal of Neurochemistry. 136:49-62
Microglia are a specialized population of myeloid cells that mediate CNS innate immune responses. Efforts to identify the cellular and molecular mechanisms that regulate microglia behaviors have been hampered by the lack of effective tools for manipu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00c11fdfeff7ca57727e00be1dd3d49
https://doi.org/10.1111/jnc.13081
https://doi.org/10.1111/jnc.13081
Autor:
C. Dirk Keene, Eiron Cudaback, Samuel R Josephsen, Macarena S. Aloi, Thomas J. Montine, Nikolas L. Jorstad, Samantha Rice, Yue Yang
Publikováno v:
Laboratory Investigation. 94:1224-1236
Frontotemporal dementia (FTD) is a neurodegenerative disease with devastating changes in behavioral performance and social function. Mutations in the progranulin gene (GRN) are one of the most common causes of inherited FTD due to reduced progranulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30870172b25cb9f838e2c3272d40a68
https://doi.org/10.1038/labinvest.2014.113
https://doi.org/10.1038/labinvest.2014.113
Publikováno v:
Critical reviews in immunology. 35(5)
The tumor-suppressor protein p53 belongs to a family of proteins that play pivotal roles in multiple cellular functions including cell proliferation, cell death, genome stability, and regulation of inflammation. Neuroinflammation is a common feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a909ab9bad377608b0bdd2053355af4a
https://pubmed.ncbi.nlm.nih.gov/26853851
https://pubmed.ncbi.nlm.nih.gov/26853851
Publikováno v:
Brain, behavior, and immunity. 52
MicroRNAs (miRNAs) are a family of small non-coding RNAs (~22 nucleotides) that fine-tune protein expression by either silencing mRNA translation or directly targeting gene transcripts for degradation. In the central nervous system (CNS), neuroinflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0a09a911aaf17c5b1baa807fe2e642
https://pubmed.ncbi.nlm.nih.gov/26148445
https://pubmed.ncbi.nlm.nih.gov/26148445