Výsledky vyhledávání - "Macarena Robledo"

HLA Class II Antibody Activation of Endothelial Cells Promotes Th17 and Disrupts Regulatory T Lymphocyte Expansion

Autor: E. Mariotto, A. Savenay, Macarena Robledo-Sarmiento, Dominique Charron, Caroline Suberbielle, Nuala Mooney, Amy Cross, Denis Glotz, Cécile Taflin, Julien Lion, Alain Haziot, Maryvonnick Carmagnat

Publikováno v: American Journal of Transplantation
American Journal of Transplantation, 2016, 16 (5), pp.1408-1420. ⟨10.1111/ajt.13644⟩
American Journal of Transplantation, Wiley, 2016, 16 (5), pp.1408-1420. ⟨10.1111/ajt.13644⟩
Europe PubMed Central

Kidney transplantation is the most successful treatment option for patients with end-stage renal disease, and chronic antibody-mediated rejection is the principal cause of allograft loss. Predictive factors for chronic rejection include high levels o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4690d5f37668efd5e128fed27976daec
https://hal.science/hal-02325476

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Mycobacterium bovis BCG-infected neutrophils and dendritic cells cooperate to induce specific T cell responses in humans and mice

Autor: Macarena Robledo, Sarah Boudaly, Nathalie Winter, Céline Morel, Jean Claude Gluckman, Valérie Abadie, Brigitte Gicquel, Niclas Setterblad, Edgar Badell

Publikováno v: European Journal of Immunology
European Journal of Immunology, Wiley-VCH Verlag, 2008, 38 (2), pp.437-447. ⟨10.1002/eji.2007379051⟩
European Journal of Immunology, 2008, 38 (2), pp.437-447. ⟨10.1002/eji.2007379051⟩

International audience; Neutrophils are increasingly thought to modulate dendritic cell (DC) functions. We investigated the role of the neutrophil-DC partnership in the response to Mycobacterium bovis BCG-the vaccine used against tuberculosis. We com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9842042ff04be25eb5f3174326de622
https://doi.org/10.1002/eji.200737905

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Polymorphonuclear neutrophils deliver activation signals and antigenic molecules to dendritic cells: a new link between leukocytes upstream of T lymphocytes

Autor: Sarah Boudaly, Macarena Robledo-Sarmiento, Jean Claude Gluckman, Anna Maria Megiovanni, Françoise Sanchez, Céline Morel

Publikováno v: Journal of Leukocyte Biology. 79:977-988

Polymorphonuclear neutrophils (PMNs) are rapidly recruited to tissues upon injury or infection. There, they can encounter local and/or recruited immature dendritic cells (iDCs), a colocalization that could promote at least transient interactions and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90120475c4e33fff8689480e90fa72d
https://doi.org/10.1189/jlb.0905526

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Identification of TMEM131L as a novel regulator of thymocyte proliferation in humans

Autor: Aude Parcelier, Niclas Setterblad, Jean Claude Gluckman, Simona Denti, Elisabeth Nelson, Veronique Parietti, Bruno Canque, Marika Pla, Nesrine Maharzi, François Sigaux, Macarena Robledo-Sarmiento

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 190(12)

In this study, we identify transmembrane protein 131–like (TMEM131L) as a novel regulator of thymocyte proliferation and demonstrate that it corresponds to a not as yet reported inhibitor of Wnt signaling. Short hairpin RNA–mediated silencing of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5c17050614594395490b210db4bb7b
https://pubmed.ncbi.nlm.nih.gov/23690469

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Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

Autor: Pier Paolo Pandolfi, Macarena Robledo-Sarmiento, Valérie Lallemand-Breitenbach, Philippe Rousselot, Rihab Nasr, Bernard Gourmel, Hassan Soilihi, Caroline Berthier, Jun Zhu, Laurent Peres, Omar Ferhi, Marie-Claude Guillemin, Dominique Vitoux, Cécile Rochette-Egly

Publikováno v: Nature Medicine
Nature Medicine, 2008, 14 (12), pp.1333-42. ⟨10.1038/nm.1891⟩
Nature Medicine, Nature Publishing Group, 2008, 14 (12), pp.1333-42. ⟨10.1038/nm.1891⟩
Nature Medicine, Nature Publishing Group, 2008, 14 (12), pp.1333-42. 〈10.1038/nm.1891〉

International audience; Retinoic acid and arsenic trioxide target the protein stability and transcriptional repression activity of the fusion oncoprotein PML-RARA, resulting in regression of acute promyelocytic leukemia (APL). Phenotypically, retinoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22618929217386a94e273b214059d7b9
https://pubmed.ncbi.nlm.nih.gov/19111876

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The promyelocytic leukemia zinc finger protein down-regulates apoptosis and expression of the proapoptotic BID protein in lymphocytes

Autor: Rose Ann Padua, Antonio Parrado, Luis Marín, Macarena Robledo, Christine Chomienne, M. Rocío Álvarez-López, M. Rosa Moya-Quiles

The promyelocytic leukemia zinc finger ( PLZF ) gene, involved in rare cases of acute promyelocytic leukemia, encodes a Krüppel-type zinc finger transcription factor. It has been reported that PLZF affects myeloid cell growth, differentiation, and a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4f3d4ef60c57e316ffdb2238b71f8a
https://europepmc.org/articles/PMC357024/

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Retinoic acid receptor alpha1 variants, RARalpha1DeltaB and RARalpha1DeltaBC, define a new class of nuclear receptor isoforms

Autor: Antonio Parrado, Isabelle Le Gall, Macarena Robledo, Jérôme Larghero, Rose Ann Padua, Gilles Despouy, Hung Bui, Cécile Rochette-Egly, Christine Chomienne, Radhia Kraïba, Maryline Choquette, Carole Le Pogam, Stéphane Dupas

Publikováno v: Nucleic acids research. 29(24)

Retinoic acid (RA) binds and activates retinoid X receptor (RXR)/retinoic acid receptor (RAR) heterodimers, which regulate the transcription of genes that have retinoic acid response elements (RARE). The RAR isotypes (alpha, beta and gamma) are compr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57158f6d04d98f79744c65d930d405fb
https://pubmed.ncbi.nlm.nih.gov/11812818

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