Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Macarena I. De La Fuente"'
Autor:
Jonathan B. Bell, William Jin, Mohammed Z. Goryawala, Gregory A. Azzam, Matthew C. Abramowitz, Tejan Diwanji, Michael E. Ivan, Maria del Pilar Guillermo Prieto Eibl, Macarena I. de la Fuente, Eric A. Mellon
Publikováno v:
Radiation Oncology, Vol 18, Iss 1, Pp 1-8 (2023)
Abstract Background Glioblastoma (GBM) cellularity correlates with whole brain spectroscopic MRI (sMRI) generated relative choline to N-Acetyl-Aspartate ratio (rChoNAA) mapping. In recurrent GBM (rGBM), tumor volume (TV) delineation is challenging an
Externí odkaz:
https://doaj.org/article/2c2f8cec5a8147c0872508e5ed6a78f1
Autor:
Dalissa Tejera, Marina Kushnirsky, Sakir H Gultekin, Min Lu, Lori Steelman, Macarena I de la Fuente
Publikováno v:
CNS Oncology, Vol 9, Iss 3 (2020)
Glioblastoma is the most common and aggressive primary brain tumor. Despite standard multimodality therapy, median overall survival remains poor with a 5-year survival rate of approximately 5% in most studies (range 4.7–13.0%). Strong interest in t
Externí odkaz:
https://doaj.org/article/4d1d7c5a294e4900b9c56edc3f87c21a
Autor:
David M. Hyman, Funda Meric-Bernstam, David B. Solit, Barry S. Taylor, José Baselga, Richard Bryce, Alshad S. Lalani, Melanie Dujka, Lisa D. Eli, Feng Xu, Grace Mann, Maurizio Scaltriti, Yanyan Cai, Aliaksandra Samoila, Myra Melcer, S. Duygu Selcuklu, Catherine Zimel, Elena I. Gavrila, Komal Jhaveri, Sarat Chandarlapaty, Gary A. Ulaner, Rebecca J. Nagy, Richard B. Lanman, Alexander N. Gorelick, François-Clement Bidard, Andrés Cervantes, Xavier Gonzàlez-Farré, Lee S. Schwartzberg, Joohyuk Sohn, Valentina Boni, Victor Moreno, Monica Arnedos, Morten Mau-Sørensen, Iben Spanggaard, Adam M. Brufksy, Macarena I. de la Fuente, Carlos L. Arteaga, Ingrid A. Mayer, Dejan Juric, Geoffrey I. Shapiro, Janice Lu, Sherene Loi, Cristina Saura, Alison M. Schram, Helen H. Won, Sarina A. Piha-Paul, Lillian M. Smyth
Overall sequencing CONSORT diagram. Flow diagram of study patients and analyzed biospecimens processed through and selected for central sequencing using MSK-IMPACT and Guardant360. cfDNA, cell-free DNA; FFPE, formalin-fixed paraffin-embedded; MSK-IMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadd31b50eb28b778540b40ef3547376
https://doi.org/10.1158/2159-8290.22535392.v1
https://doi.org/10.1158/2159-8290.22535392.v1
Autor:
David M. Hyman, Funda Meric-Bernstam, David B. Solit, Barry S. Taylor, José Baselga, Richard Bryce, Alshad S. Lalani, Melanie Dujka, Lisa D. Eli, Feng Xu, Grace Mann, Maurizio Scaltriti, Yanyan Cai, Aliaksandra Samoila, Myra Melcer, S. Duygu Selcuklu, Catherine Zimel, Elena I. Gavrila, Komal Jhaveri, Sarat Chandarlapaty, Gary A. Ulaner, Rebecca J. Nagy, Richard B. Lanman, Alexander N. Gorelick, François-Clement Bidard, Andrés Cervantes, Xavier Gonzàlez-Farré, Lee S. Schwartzberg, Joohyuk Sohn, Valentina Boni, Victor Moreno, Monica Arnedos, Morten Mau-Sørensen, Iben Spanggaard, Adam M. Brufksy, Macarena I. de la Fuente, Carlos L. Arteaga, Ingrid A. Mayer, Dejan Juric, Geoffrey I. Shapiro, Janice Lu, Sherene Loi, Cristina Saura, Alison M. Schram, Helen H. Won, Sarina A. Piha-Paul, Lillian M. Smyth
HER2 mutations define a subset of metastatic breast cancers with a unique mechanism of oncogenic addiction to HER2 signaling. We explored activity of the irreversible pan-HER kinase inhibitor neratinib, alone or with fulvestrant, in 81 patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df3c52be345cb95e67d14e31497f606f
https://doi.org/10.1158/2159-8290.c.6547849.v1
https://doi.org/10.1158/2159-8290.c.6547849.v1
Autor:
David M. Hyman, Funda Meric-Bernstam, David B. Solit, Barry S. Taylor, José Baselga, Richard Bryce, Alshad S. Lalani, Melanie Dujka, Lisa D. Eli, Feng Xu, Grace Mann, Maurizio Scaltriti, Yanyan Cai, Aliaksandra Samoila, Myra Melcer, S. Duygu Selcuklu, Catherine Zimel, Elena I. Gavrila, Komal Jhaveri, Sarat Chandarlapaty, Gary A. Ulaner, Rebecca J. Nagy, Richard B. Lanman, Alexander N. Gorelick, François-Clement Bidard, Andrés Cervantes, Xavier Gonzàlez-Farré, Lee S. Schwartzberg, Joohyuk Sohn, Valentina Boni, Victor Moreno, Monica Arnedos, Morten Mau-Sørensen, Iben Spanggaard, Adam M. Brufksy, Macarena I. de la Fuente, Carlos L. Arteaga, Ingrid A. Mayer, Dejan Juric, Geoffrey I. Shapiro, Janice Lu, Sherene Loi, Cristina Saura, Alison M. Schram, Helen H. Won, Sarina A. Piha-Paul, Lillian M. Smyth
Supplementary data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9a66139c86c7fc9c7963ce2aff13cc
https://doi.org/10.1158/2159-8290.22535398
https://doi.org/10.1158/2159-8290.22535398
Autor:
Beatriz Guevara, Kaylie Cullison, Danilo Maziero, Gregory A. Azzam, Macarena I. De La Fuente, Karen Brown, Alessandro Valderrama, Jessica Meshman, Adrian Breto, John Chetley Ford, Eric A. Mellon
Publikováno v:
Cancers
Volume 15
Issue 5
Pages: 1555
Volume 15
Issue 5
Pages: 1555
During radiation therapy (RT) of glioblastoma, daily MRI with combination MRI–linear accelerator (MRI–Linac) systems has demonstrated significant anatomic changes, including evolving post-surgical cavity shrinkage. Cognitive function RT for brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5d58611eb3b7bd69eb27aa1e1984c8
Autor:
Macarena I de la Fuente, Howard Colman, Mark Rosenthal, Brian A Van Tine, Danijela Levacic, Tobias Walbert, Hui K Gan, Maria Vieito, Mohammed M Milhem, Kathryn Lipford, Sanjeev Forsyth, Sylvie M Guichard, Yelena Mikhailov, Alexander Sedkov, Julie Brevard, Patrick F Kelly, Hesham Mohamed, Varun Monga
Publikováno v:
Scientia
Background Olutasidenib (FT-2102) is a highly potent, orally bioavailable, brain-penetrant and selective inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). The aim of the study was to determine the safety and clinical activity of olutasidenib in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b253bb132081b03fc3679216acf7f5
https://doi.org/10.1093/neuonc/noac139
https://doi.org/10.1093/neuonc/noac139
Autor:
Macarena I. de la Fuente
Publikováno v:
Current opinion in neurology. 35(6)
Somatic point mutations in the metabolic enzyme isocitrate dehydrogenase (IDH) are a defining feature of the majority of WHO grade 2-3 diffuse glioma and the most powerful positive prognostic factor for survival in gliomas. The purpose is to review e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a953bc4347a86fab38033bf14c9ab376
https://pubmed.ncbi.nlm.nih.gov/36367045
https://pubmed.ncbi.nlm.nih.gov/36367045
Autor:
Alyx B. Porter, Macarena I. de la Fuente, Sadhana Jackson, Erin M. Dunbar, Ekokobe Fonkem, Akanksha Sharma, Terri S. Armstrong, Na Tosha Gatson, Shawn L. Hervey-Jumper, Elizabeth Vera, Laura J. Klesse, Yazmin Odia, Alvina Acquaye, Alissa A. Thomas, Ugonma Chukwueke, Sandra Camelo-Piragua, Tamra E. Werbowetski-Ogilvie
Publikováno v:
Neuro Oncol
Background Neuro-oncology has grown tremendously since 2010, marked by increasing society membership, specialized clinical expertise, and new journals. Yet, modest improvement in racial/ethnic diversity amongst clinical trial participants, researcher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088bb92c7b57c31580412b73c6998664
https://doi.org/10.1093/neuonc/noab172
https://doi.org/10.1093/neuonc/noab172
Autor:
Elizabeth A. Maher, Benjamin M. Ellingson, Sung Choe, Saewon Chun, Marta Penas-Prado, Hua Liu, Lori Steelman, Patrick Y. Wen, Jennifer Clarke, Ingo K. Mellinghoff, Katherine B. Peters, Robert J. Young, Shuchi Sumant Pandya, Min Lu, Timothy F. Cloughesy, Howard A. Burris, Macarena I. de la Fuente, Filip Janku, Kha Le, Gregory M. Cote, Islam Hassan
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 27, iss 16
Clin Cancer Res
Clin Cancer Res
Purpose: Lower grade gliomas (LGGs) are malignant brain tumors. Current therapy is associated with short- and long-term toxicity. Progression to higher tumor grade is associated with contrast enhancement on MRI. The majority of LGGs harbor mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac86539fe4e5156e90351b80f2f304f
https://doi.org/10.1158/1078-0432.ccr-21-0611
https://doi.org/10.1158/1078-0432.ccr-21-0611