Red blood cell flickering activity locally controlled by holographic optical tweezers

Autor: Niccolò Caselli, Mario García-Verdugo, Macarena Calero, Natalia Hernando-Ospina, José A. Santiago, Diego Herráez-Aguilar, Francisco Monroy

Publikováno v: iScience, Vol 27, Iss 6, Pp 109915- (2024)

Summary: Red blood cells possess a singular mechanobiology, enabling efficient navigation through capillaries smaller than their own size. Their plasma membrane exhibits non-equilibrium shape fluctuation, often reported as enhanced flickering activit

Externí odkaz: https://doaj.org/article/f5b80413ed124d08a805d797055ec90f

Recapitulating Solid Stress on Tumor on a Chip for Nanomedicine Diffusive Transport Prediction

Autor: Alberto Martín-Asensio, Sergio Dávila, Jean Cacheux, Agnieszka Lindstaedt, Alicja Dziadosz, Darius Witt, Macarena Calero, Igor Balaz, Isabel Rodríguez

Publikováno v: Advanced NanoBiomed Research, Vol 3, Iss 6, Pp n/a-n/a (2023)

The characteristic mechanical forces at play within tumors include the abnormal solid and fluid stresses. These, together with the increased extracellular matrix (ECM) stiffness, are the major transport barriers affecting the nanomedicine delivery to

Externí odkaz: https://doaj.org/article/f702c5bbd5224523bfeb511b949a6f4d

Erythroid SLC7A5/SLC3A2 amino acid carrier controls red blood cell size and maturation

Autor: Antonio Bouthelier, Lucía Fernández-Arroyo, Claudia Mesa-Ciller, Danay Cibrian, Noa Beatriz Martín-Cófreces, Raquel Castillo-González, Macarena Calero, Diego Herráez-Aguilar, Andrea Guajardo-Grence, Ana María Pacheco, Ana Marcos-Jiménez, Borja Quiroga, Marta Morado, Francisco Monroy, Cecilia Muñoz-Calleja, Francisco Sánchez-Madrid, Andrés A. Urrutia, Julián Aragonés

Publikováno v: iScience, Vol 26, Iss 1, Pp 105739- (2023)

Summary: Inhibition of the heterodimeric amino acid carrier SLC7A5/SLC3A2 (LAT1/CD98) has been widely studied in tumor biology but its role in physiological conditions remains largely unknown. Here we show that the SLC7A5/SLC3A2 heterodimer is consti

Externí odkaz: https://doaj.org/article/9f88a225d2a34608ab1186ab95692670

Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells

Autor: Rodolfo Miranda, Álvaro Somoza, Robert Clarke, Ana Lazaro-Carrillo, Macarena Calero, Alfonso Latorre, Aitziber L. Cortajarena, Bruno M Simões, Angeles Villanueva, Antonio Aires

Publikováno v: Cancers
Volume 12
Issue 6
Lazaro-Carrillo, A, Calero, M, Aires, A, L Cortajarena, A, Simões, B M, Latorre, A, Somoza, Á, Clarke, R B, Miranda, R & Villanueva, A 2020, ' Tailored Functionalized Magnetic Nanoparticles to Target Breast Cancer Cells Including Cancer Stem-Like Cells ', Cancers, vol. 12, no. 6 . https://doi.org/10.3390/cancers12061397
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
Cancers, Vol 12, Iss 1397, p 1397 (2020)

Nanotechnology-based approaches hold substantial potential to avoid chemoresistance and minimize side effects. In this work, we have used biocompatible iron oxide magnetic nanoparticles (MNPs) called MF66 and functionalized with the antineoplastic dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161dd75c6c53e844a186b9cf02b5a903
http://europepmc.org/articles/PMC7352336

Efficient and safe internalization of magnetic iron oxide nanoparticles: Two fundamental requirements for biomedical applications

Autor: Macarena Calero, M. Puerto Morales, Pilar Acedo, Yurena Luengo, Ana Lázaro, Gorka Salas, Rodolfo Miranda, Angeles Villanueva, Lucía Gutiérrez

Publikováno v: Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
instname
Digital.CSIC. Repositorio Institucional del CSIC

We have performed a series of in vitro tests proposed for the reliable assessment of safety associated with nanoparticles-cell interaction. A thorough analysis of toxicity of three different coating iron oxide nanoparticles on HeLa cells has been car

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa8937a8baf2e8e922b83401accc3b6
https://doi.org/10.1016/j.nano.2013.11.010