SHC-3: a previously unidentified C. elegans Shc family member functions in the insulin-like signaling pathway to enhance survival during L1 arrest.

Autor: Di Bernardo M; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON L8S 4K1, Canada., León Guerrero VL; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON L8S 4K1, Canada., Sutoski JC; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON L8S 4K1, Canada., Hardy WR; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON L8S 4K1, Canada., MacNeil LT; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON L8S 4K1, Canada.; Farncombe Family Digestive Health Research Institute, McMaster University, 1280 Main St W, Hamilton, ON L8S 4K1, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, 1280 Main St W, Hamilton, ON L8S 4K1, Canada.

Publikováno v: Genetics [Genetics] 2024 Oct 07; Vol. 228 (2).

Lessons from assembling a microbial natural product and pre-fractionated extract library in an academic laboratory.

Autor: Cook MA; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Pallant D; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Ejim L; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Sutherland AD; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Wang X; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Johnson JW; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., McCusker S; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Chen X; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., George M; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Chou S; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.; Farncombe Family Digestive Health Research Institute, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada., Koteva K; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Wang W; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Hobson C; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Hackenberger D; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Waglechner N; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Ejim O; College of Medicine, Enugu State University of Science and Technology, Agbani, Enugu State, PMB 01660, Nigeria., Campbell T; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada., Medina R; Department of Microbiology, Chemical Bioactive Center, Central University Marta Abreu de las Villas, Santa Clara 54830, Villa Clara, Cuba., MacNeil LT; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.; Farncombe Family Digestive Health Research Institute, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada., Wright GD; Department of Biochemistry and Biomedical Sciences, M.G. DeGroote Institute for Infectious Disease Research, DeGroote School of Medicine, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4K1, Canada.

Publikováno v: Journal of industrial microbiology & biotechnology [J Ind Microbiol Biotechnol] 2023 Feb 17; Vol. 50 (1).

Free long-chain fatty acids trigger early postembryonic development in starved Caenorhabditis elegans by suppressing mTORC1.

Autor: Ruan, Meiyu¹ (AUTHOR), Xu, Fan¹ (AUTHOR), Li, Na¹ (AUTHOR), Yu, Jing² (AUTHOR), Teng, Fukang¹ (AUTHOR), Tang, Jiawei¹ (AUTHOR), Huang, Cheng² (AUTHOR), Zhu, Huanhu¹ (AUTHOR) zhuhh1@Shanghaitech.edu.cn

Publikováno v: PLoS Biology. 10/22/2024, Vol. 22 Issue 10, p1-30. 30p.

Cuticle Collagen Expression Is Regulated in Response to Environmental Stimuli by the GATA Transcription Factor ELT-3 in Caenorhabditis elegans .

Autor: Mesbahi H; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada L8S 4K1., Pho KB; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada L8S 4K1., Tench AJ; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada L8S 4K1., Leon Guerrero VL; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada L8S 4K1., MacNeil LT; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada L8S 4K1 macneil@mcmaster.ca.; Farncombe Family Digestive Health Research Institute, McMaster University, Ontario, Canada.; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada L8S 4K1.

Publikováno v: Genetics [Genetics] 2020 Jun; Vol. 215 (2), pp. 483-495. Date of Electronic Publication: 2020 Mar 30.

Bacteria transmit metformin-associated lifespan extension.

Autor: MacNeil LT; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada., Schertzer JD; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada.; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada., Steinberg GR; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada. gsteinberg@mcmaster.ca.; Centre for Metabolism, Obesity and Diabetes Research, McMaster University, Hamilton, Ontario, Canada. gsteinberg@mcmaster.ca.; Division of Endocrinology and Metabolism, Department of Medicine, McMaster University, Hamilton, Ontario, Canada. gsteinberg@mcmaster.ca.

Publikováno v: Nature reviews. Endocrinology [Nat Rev Endocrinol] 2020 Jan; Vol. 16 (1), pp. 9-10.