Zobrazeno 1 - 10
of 813
pro vyhledávání: '"MacNee William"'
Publikováno v:
Respiratory Research, Vol 1, Iss 1, Pp 12-15 (2000)
Abstract PM10 (the mass of particles present in the air having a 50% cutoff for particles with an aerodynamic diameter of 10 μm) is the standard measure of particulate air pollution used worldwide. Epidemiological studies suggest that asthma symptom
Externí odkaz:
https://doaj.org/article/5074afc40c7f4d0d80ee36607b271d31
Autor:
Bradley Mark, MacNee William, Wallace William AH, Scotton Chris J, Howie Sarah EM, Duffin Rodger, Cho Wan-Seob, Megson Ian L, Donaldson Ken
Publikováno v:
Particle and Fibre Toxicology, Vol 8, Iss 1, p 27 (2011)
Abstract Background Large production volumes of zinc oxide nanoparticles (ZnONP) might be anticipated to pose risks, of accidental inhalation in occupational and even in consumer settings. Herein, we further investigated the pathological changes indu
Externí odkaz:
https://doaj.org/article/efd40c9eaeec4e0c82fd462a843dc5ff
Autor:
Stolk Jan, MacNee William, Keatings Vera, Donnelly Seamas C, Millar Ann B, Morgan Kevin, Rabinovich Roberto, Roca Josep, Guetta-Baranes Tamar, Alsaegh Aiman, Lotya Juzer, Daly Leslie, Chappell Sally L, Hiemstra Pieter S, Miniati Massimo, Monti Simonetta, O'Connor Clare M, Kalsheker Noor
Publikováno v:
BMC Medical Genetics, Vol 12, Iss 1, p 24 (2011)
Abstract Background Genetic factors are known to contribute to COPD susceptibility and these factors are not fully understood. Conflicting results have been reported for many genetic studies of candidate genes based on their role in the disease. Geno
Externí odkaz:
https://doaj.org/article/a08c334c903840eb8ee4a27d1a78f1aa
Autor:
Agusti Alvar, Calverley Peter MA, Celli Bartolome, Coxson Harvey O, Edwards Lisa D, Lomas David A, MacNee William, Miller Bruce E, Rennard Steve, Silverman Edwin K, Tal-Singer Ruth, Wouters Emiel, Yates Julie C, Vestbo Jørgen
Publikováno v:
Respiratory Research, Vol 11, Iss 1, p 122 (2010)
Abstract Background Chronic obstructive pulmonary disease (COPD) is a complex condition with pulmonary and extra-pulmonary manifestations. This study describes the heterogeneity of COPD in a large and well characterised and controlled COPD cohort (EC
Externí odkaz:
https://doaj.org/article/d6063e81b33645ebbe5acdc138057f32
Autor:
Stevenson Christopher S, Arunachalam Gnanapragasam, Edirisinghe Indika, Marwick John A, MacNee William, Kirkham Paul A, Rahman Irfan
Publikováno v:
Journal of Inflammation, Vol 7, Iss 1, p 11 (2010)
Abstract Background Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (VEGFR2)-mediated survival signaling is critical to endothelial cell survival, maintenance of the vasculature and alveolar structure and regeneration of lung tissue. Re
Externí odkaz:
https://doaj.org/article/054643723edb44d89de1c6e48ea39f06
Autor:
Keatings Vera, Donnelly Seamas C, Millar Ann B, Rabinovich Roberto, Roca Josep, Guetta-Baranes Tamar, Morgan Kevin, Daly Leslie, Lotya Juzer, Johnson Simon R, Chappell Sally, Haq Imran, MacNee William, Stolk Jan, Hiemstra Pieter S, Miniati Massimo, Monti Simonetta, O'Connor Clare M, Kalsheker Noor
Publikováno v:
BMC Medical Genetics, Vol 11, Iss 1, p 7 (2010)
Abstract Background Genetic factors play a role in chronic obstructive pulmonary disease (COPD) but are poorly understood. A number of candidate genes have been proposed on the basis of the pathogenesis of COPD. These include the matrix metalloprotei
Externí odkaz:
https://doaj.org/article/92f088fa2cbf4ad2aeb30d5a85697ce6
Autor:
Verschakelen Johny, Verbeken Eric K, Nicholson Andrew G, Laurent Francois, Wallaert Benoit, Thomeer Michiel, MacNee William, Jansen Henk M, Dekhuijzen Richard PN, Costabel Ulrich, Buhl Roland, Demedts Maurits, Behr Jürgen, Flower CDR, Petruzzelli Stefano, De Vuyst Paul, Bosch JMM, Rodriguez-Becerra Eulogio, Lankhorst Ida, Sardina Marco, Boissard Gabrielle
Publikováno v:
Respiratory Research, Vol 10, Iss 1, p 101 (2009)
Abstract Background The randomized placebo-controlled IFIGENIA-trial demonstrated that therapy with high-dose N-acetylcysteine (NAC) given for one year, added to prednisone and azathioprine, significantly ameliorates (i.e. slows down) disease progres
Externí odkaz:
https://doaj.org/article/a085b93fec10443ea8df6544651850c9
Autor:
Mills Nicholas, Newby David E, Duffin Rodger, Jimenez Luis, Tran Lang, Donaldson Ken, MacNee William, Stone Vicki
Publikováno v:
Particle and Fibre Toxicology, Vol 2, Iss 1, p 10 (2005)
Abstract This review considers the molecular toxicology of combustion-derived nanoparticles (CDNP) following inhalation exposure. CDNP originate from a number of sources and in this review we consider diesel soot, welding fume, carbon black and coal
Externí odkaz:
https://doaj.org/article/020de6b7c66f4fecae8da35fa57dd78d
Autor:
Drummond, M. Bradley, MacNee, William
Patients with COPD often make few complaints despite experiencing considerable disability. As well as the characteristic shortness of breath, the disease is associated with a number of comorbidities that can present major clinical problems. However,
Publikováno v:
Environmental Health Perspectives, 2001 Aug 01. 109, 523-527.
Externí odkaz:
https://www.jstor.org/stable/3454663