Unique immune and inflammatory cytokine profiles may define long COVID syndrome.

Autor: Allan-Blitz LT; Division of Global Health Equity: Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA. lallan-blitz@partners.org., Akbari O; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA., Kojima N; Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Saavedra E; Curative Inc., San Dimas, CA, USA., Chellamuthu P; Curative Inc., San Dimas, CA, USA., Denny N; Curative Inc., San Dimas, CA, USA., MacMullan MA; Curative Inc., San Dimas, CA, USA., Hess V; Curative Inc., San Dimas, CA, USA., Shacreaw M; Curative Inc., San Dimas, CA, USA., Brobeck M; Curative Inc., San Dimas, CA, USA., Turner F; Curative Inc., San Dimas, CA, USA., Slepnev VI; Curative Inc., San Dimas, CA, USA., Ibrayeva A; Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Klausner JD; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.

Publikováno v: Clinical and experimental medicine [Clin Exp Med] 2023 Oct; Vol. 23 (6), pp. 2925-2930. Date of Electronic Publication: 2023 Apr 16.

A bidirectional switch in the Shank3 phosphorylation state biases synapses toward up- or downscaling.

Autor: Wu CH; Department of Biology, Brandeis University, Waltham, United States., Tatavarty V; Department of Biology, Brandeis University, Waltham, United States., Jean Beltran PM; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Guerrero AA; Department of Biology, Brandeis University, Waltham, United States., Keshishian H; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Krug K; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., MacMullan MA; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Li L; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, United States., Carr SA; Proteomics Platform, Broad Institute of MIT and Harvard, Cambridge, United States., Cottrell JR; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, United States., Turrigiano GG; Department of Biology, Brandeis University, Waltham, United States.

Publikováno v: ELife [Elife] 2022 Apr 26; Vol. 11. Date of Electronic Publication: 2022 Apr 26.

SARS-CoV-2 Specific IgG Antibodies Persist Over a 12-Month Period in Oral Mucosal Fluid Collected From Previously Infected Individuals.

Autor: Chellamuthu P; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Angel AN; Department of Serology Research and Development, Curative, Monrovia, CA, United States., MacMullan MA; Department of Serology Research and Development, Curative, Monrovia, CA, United States.; Mork Family Department of Chemical Engineering and Materials Science, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, United States., Denny N; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Mades A; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Santacruz M; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Lopez R; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Bagos C; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Casian JG; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Trettner K; Department of Serology Research and Development, Curative, Monrovia, CA, United States.; Mork Family Department of Chemical Engineering and Materials Science, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, United States., Lopez L; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Nirema N; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Brobeck M; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Kojima N; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States., Klausner JD; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States., Turner F; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Slepnev V; Department of Serology Research and Development, Curative, Monrovia, CA, United States., Ibrayeva A; Department of Serology Research and Development, Curative, Monrovia, CA, United States.; Eli and Edythe Broad Center for Regenerative Medicine at the University of Southern California, William Myron Keck School of Medicine, Los Angeles, CA, United States.; Davis School of Gerontology, University of Southern California, Los Angeles, CA, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Dec 09; Vol. 12, pp. 777858. Date of Electronic Publication: 2021 Dec 09 (Print Publication: 2021).

A highly multiplexed quantitative phosphosite assay for biology and preclinical studies.

Autor: Keshishian H; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., McDonald ER 3rd; Novartis Institute of Biomedical Research, Cambridge, MA, USA., Mundt F; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Melanson R; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Krug K; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Porter DA; Novartis Institute of Biomedical Research, Cambridge, MA, USA., Wallace L; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Forestier D; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Rabasha B; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Marlow SE; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Jane-Valbuena J; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Todres E; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Specht H; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Robinson ML; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Jean Beltran PM; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Babur O; Computer Science Department, University of Massachusetts Boston, Boston, MA, USA., Olive ME; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Golji J; Novartis Institute of Biomedical Research, Cambridge, MA, USA., Kuhn E; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Burgess M; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., MacMullan MA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Rejtar T; Novartis Institute of Biomedical Research, Cambridge, MA, USA., Wang K; Novartis Institute of Biomedical Research, Cambridge, MA, USA., Mani DR; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Satpathy S; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA., Gillette MA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, USA., Sellers WR; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA., Carr SA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA.

Publikováno v: Molecular systems biology [Mol Syst Biol] 2021 Sep; Vol. 17 (9), pp. e10156.

Detection of SARS-CoV-2 Antibodies in Oral Fluid Obtained Using a Rapid Collection Device.

Autor: MacMullan MA; Curative Inc., San Dimas, California, USA.; Mork Family Department of Chemical Engineering and Materials Science, Viterbi School of Engineering, University of Southern California, Los Angeles, California, USA., Chellamuthu P; Curative Inc., San Dimas, California, USA., Mades A; Curative Inc., San Dimas, California, USA., Das S; Curative Inc., San Dimas, California, USA., Turner F; Curative Inc., San Dimas, California, USA., Slepnev VI; Curative Inc., San Dimas, California, USA Vlad.slepnev@curative.com albina@curative.com., Ibrayeva A; Curative Inc., San Dimas, California, USA Vlad.slepnev@curative.com albina@curative.com.; Eli and Edythe Broad Center for Regenerative Medicine & Stem Cell Research at USC, Department of Stem Cell Biology and Regenerative Medicine, W.M. Keck School of Medicine, University of Southern California, Los Angeles, California, USA.; Davis School of Gerontology, University of Southern California, Los Angeles, California, USA.

Publikováno v: Journal of clinical microbiology [J Clin Microbiol] 2021 Jan 21; Vol. 59 (2). Date of Electronic Publication: 2021 Jan 21 (Print Publication: 2021).