Zobrazeno 1 - 10
of 52
pro vyhledávání: '"MacLean P Nasrallah"'
Autor:
Igor Makhlin, Ryan D Salinas, Daniel Zhang, Fadi Jacob, Gou-li Ming, Hongjun Song, Deeksha Saxena, Jay F Dorsey, MacLean P Nasrallah, Jennifer JD Morrissette, Zev A Binder, Donald M O'Rourke, Arati S Desai, Steven Brem, Stephen J Bagley
Publikováno v:
CNS Oncology, Vol 8, Iss 3 (2019)
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults and carries a dismal prognosis. The EGFR gene is among the most commonly deranged genes in GBM and thus an important therapeutic target. We report the case of a young femal
Externí odkaz:
https://doaj.org/article/03959e296e524237be76b58b81c7e0c8
Autor:
Laiz Laura de Godoy, Suyash Mohan, Sumei Wang, MacLean P. Nasrallah, Yu Sakai, Donald M. O’Rourke, Stephen Bagley, Arati Desai, Laurie A. Loevner, Harish Poptani, Sanjeev Chawla
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Accurate differentiation of pseudoprogression (PsP) from tumor progression (TP) in glioblastomas (GBMs) is essential for appropriate clinical management and prognostication of these patients. In the present study, we sought to val
Externí odkaz:
https://doaj.org/article/939f563d0d71422b9916e708c2031dea
Autor:
Spyridon Bakas, Chiharu Sako, Hamed Akbari, Michel Bilello, Aristeidis Sotiras, Gaurav Shukla, Jeffrey D. Rudie, Natali Flores Santamaría, Anahita Fathi Kazerooni, Sarthak Pati, Saima Rathore, Elizabeth Mamourian, Sung Min Ha, William Parker, Jimit Doshi, Ujjwal Baid, Mark Bergman, Zev A. Binder, Ragini Verma, Robert A. Lustig, Arati S. Desai, Stephen J. Bagley, Zissimos Mourelatos, Jennifer Morrissette, Christopher D. Watt, Steven Brem, Ronald L. Wolf, Elias R. Melhem, MacLean P. Nasrallah, Suyash Mohan, Donald M. O’Rourke, Christos Davatzikos
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-12 (2022)
Measurement(s) Magnetic Resonance Imaging Technology Type(s) Magnetic Resonance Imaging of the Brain with and without Contrast Sample Characteristic - Organism Homo sapiens Sample Characteristic - Environment brain Sample Characteristic - Location Un
Externí odkaz:
https://doaj.org/article/5d5b415e3a86419991ae9fdec07415bc
Autor:
Rachael G. Aubin, Emma C. Troisi, Javier Montelongo, Adam N. Alghalith, Maclean P. Nasrallah, Mariarita Santi, Pablo G. Camara
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The molecular mechanisms underlying ependymoma tumorigenesis remain poorly understood. Here, single cell analysis of posterior fossa primary tumours and distal metastases highlights the role of pro-inflammatory cytokines in promoting epithelial-to-me
Externí odkaz:
https://doaj.org/article/5813a87138be474398527991ba01b4e8
Autor:
Anahita Fathi Kazerooni, Sanjay Saxena, Erik Toorens, Danni Tu, Vishnu Bashyam, Hamed Akbari, Elizabeth Mamourian, Chiharu Sako, Costas Koumenis, Ioannis Verginadis, Ragini Verma, Russell T. Shinohara, Arati S. Desai, Robert A. Lustig, Steven Brem, Suyash Mohan, Stephen J. Bagley, Tapan Ganguly, Donald M. O’Rourke, Spyridon Bakas, MacLean P. Nasrallah, Christos Davatzikos
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Multi-omic data, i.e., clinical measures, radiomic, and genetic data, capture multi-faceted tumor characteristics, contributing to a comprehensive patient risk assessment. Here, we investigate the additive value and independent reproducibili
Externí odkaz:
https://doaj.org/article/2e0a631fb2f84bd8ab1d9f8f31d56f26
Autor:
Jose L. Agraz, Caleb M. Grenko, Andrew A. Chen, Angela N. Viaene, MacLean D. Nasrallah, Sarthak Pati, Tahsin Kurc, Joel Saltz, Michael D. Feldman, Hamed Akbari, Parth Sharma, Russell T. Shinohara, Spyridon Bakas
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 3, Pp 218-226 (2022)
Histopathologic evaluation of Hematoxylin & Eosin (H&E) stained slides is essential for disease diagnosis, revealing tissue morphology, structure, and cellular composition. Variations in staining protocols and equipment result in images with color no
Externí odkaz:
https://doaj.org/article/8fcd868656934650895f188afc261594
Autor:
Laiz Laura de Godoy, Sanjeev Chawla, Steven Brem, Sumei Wang, Donald M O’Rourke, MacLean P. Nasrallah, Arati Desai, Laurie A. Loevner, Linda M. Liau, Suyash Mohan
Publikováno v:
Journal of Neuro-Oncology. 163:173-183
Purpose Autologous tumor lysate-loaded dendritic cell vaccine (DCVax-L) is a promising treatment modality for glioblastomas. The purpose of this study was to investigate the potential utility of multiparametric MRI-based prediction model in evaluatin
Autor:
Joseph S. Durgin, Fraser Henderson, MacLean P. Nasrallah, Suyash Mohan, Sumei Wang, Simon F. Lacey, Jan Joseph Melenhorst, Arati S. Desai, John Y. K. Lee, Marcela V. Maus, Carl H. June, Steven Brem, Roddy S. O’Connor, Zev Binder, Donald M. O’Rourke
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Autologous chimeric antigen receptor (CAR) T cells targeted to epidermal growth factor receptor variant III (CAR T-EGFRvIII) have been developed and administered experimentally to treat patients with IDH1 wildtype recurrent glioblastoma (rGBM) (NCT02
Externí odkaz:
https://doaj.org/article/28e7edd3d6b7457386c94ed075c82476
Autor:
Ernest J. Nelson, Maria A. Gubbiotti, Alicia M. Carlin, MacLean P. Nasrallah, Vivianna M. Van Deerlin, Sarah E. Herlihy
Publikováno v:
Molecular Diagnosis & Therapy. 27:371-381
Publikováno v:
Journal of Neuro-Oncology. 161:373-381