SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway (vol 7, pg 1161, 2022)

Autor: Willett, BJ, Grove, J, MacLean, OA, Wilkie, C, De Lorenzo, G, Furnon, W, Cantoni, D, Scott, S, Logan, N, Ashraf, S, Manali, M, Szemiel, A, Cowton, V, Vink, E, Harvey, WT, Davis, C, Asamaphan, P, Smollett, K, Tong, L, Orton, R, Hughes, J, Holland, P, Silva, V, Pascall, DJ, Puxty, K, Da Silva Filipe, A, Yebra, G, Shaaban, S, Holden, MTG, Pinto, RM, Gunson, R, Templeton, K, Murcia, PR, Patel, AH, Klenerman, P, Dunachie, S, Haughney, J, Robertson, DL, Palmarini, M, Ray, S, Thomson, EC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::29f8bc5b745ce7a7eba91ab22a0727c6
http://hdl.handle.net/10044/1/105302

Correlates of disease severity in bluetongue as a model of acute arbovirus infection.

Autor: Herder V; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Caporale M; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise 'G. Caporale', Teramo, Italy., MacLean OA; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Pintus D; Istituto Zooprofilattico Sperimentale della Sardegna, Sassari, Italy., Huang X; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Nomikou K; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Palmalux N; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Nichols J; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Scivoli R; Istituto Zooprofilattico Sperimentale della Sardegna, Sassari, Italy., Boutell C; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Taggart A; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Allan J; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Malik H; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Ilia G; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Gu Q; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Ronchi GF; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise 'G. Caporale', Teramo, Italy., Furnon W; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Zientara S; Laboratory for Animal Health, INRAE, Ecole Nationale Vétérinaire d'Alfort, ANSES, Maisons-Alfort, France., Bréard E; Laboratory for Animal Health, INRAE, Ecole Nationale Vétérinaire d'Alfort, ANSES, Maisons-Alfort, France., Antonucci D; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise 'G. Caporale', Teramo, Italy., Capista S; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise 'G. Caporale', Teramo, Italy., Giansante D; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise 'G. Caporale', Teramo, Italy., Cocco A; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise 'G. Caporale', Teramo, Italy., Mercante MT; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise 'G. Caporale', Teramo, Italy., Di Ventura M; Istituto Zooprofilattico Sperimentale dell' Abruzzo e Molise 'G. Caporale', Teramo, Italy., Da Silva Filipe A; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Puggioni G; Istituto Zooprofilattico Sperimentale della Sardegna, Sassari, Italy., Sevilla N; Centro de Investigación en Sanidad Animal. Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Consejo Superior de Investigaciones Científicas (CISA-INIA-CSIC). Valdeolmos, Madrid, Spain., Stewart ME; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom., Ligios C; Istituto Zooprofilattico Sperimentale della Sardegna, Sassari, Italy., Palmarini M; MRC-University of Glasgow Centre for Virus Research, Glasgow, United Kingdom.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Aug 16; Vol. 20 (8), pp. e1012466. Date of Electronic Publication: 2024 Aug 16 (Print Publication: 2024).

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway.

Autor: Willett BJ; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK. brian.willett@glasgow.ac.uk., Grove J; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK. joe.grove@glasgow.ac.uk., MacLean OA; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Wilkie C; School of Mathematics & Statistics, University of Glasgow, Glasgow, UK., De Lorenzo G; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Furnon W; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Cantoni D; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Scott S; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Logan N; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Ashraf S; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Manali M; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Szemiel A; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Cowton V; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Vink E; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Harvey WT; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Davis C; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Asamaphan P; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Smollett K; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Tong L; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Orton R; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Hughes J; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Holland P; NHS Greater Glasgow & Clyde, Glasgow, UK., Silva V; NHS Greater Glasgow & Clyde, Glasgow, UK., Pascall DJ; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK., Puxty K; NHS Greater Glasgow & Clyde, Glasgow, UK., da Silva Filipe A; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Yebra G; Public Health Scotland, Glasgow, UK., Shaaban S; Public Health Scotland, Glasgow, UK., Holden MTG; Public Health Scotland, Glasgow, UK.; School of Medicine, University of St Andrews, St Andrews, UK., Pinto RM; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Gunson R; NHS Greater Glasgow & Clyde, Glasgow, UK., Templeton K; NHS Lothian, Edinburgh, UK., Murcia PR; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Patel AH; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Klenerman P; University of Oxford, Oxford, UK., Dunachie S; University of Oxford, Oxford, UK., Haughney J; NHS Greater Glasgow & Clyde, Glasgow, UK., Robertson DL; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Palmarini M; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK., Ray S; School of Mathematics & Statistics, University of Glasgow, Glasgow, UK., Thomson EC; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, UK. emma.thomson@glasgow.ac.uk.; NHS Greater Glasgow & Clyde, Glasgow, UK. emma.thomson@glasgow.ac.uk.; London School of Hygiene and Tropical Medicine, London, UK. emma.thomson@glasgow.ac.uk.

Publikováno v: Nature microbiology [Nat Microbiol] 2022 Aug; Vol. 7 (8), pp. 1161-1179. Date of Electronic Publication: 2022 Jul 07.

Selection Analysis Identifies Clusters of Unusual Mutational Changes in Omicron Lineage BA.1 That Likely Impact Spike Function.

Autor: Martin DP; Institute of Infectious Diseases and Molecular Medicine, Division of Computational Biology, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa., Lytras S; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom., Lucaci AG; Institute for Genomics and Evolutionary Medicine, Department of Biology, Temple University, Philadelphia, PA, USA., Maier W; Bioinformatics Group, Department of Computer Science, University of Freiburg, Freiburg, Germany, usegalaxy.eu., Grüning B; Bioinformatics Group, Department of Computer Science, University of Freiburg, Freiburg, Germany, usegalaxy.eu., Shank SD; Institute for Genomics and Evolutionary Medicine, Department of Biology, Temple University, Philadelphia, PA, USA., Weaver S; Institute for Genomics and Evolutionary Medicine, Department of Biology, Temple University, Philadelphia, PA, USA., MacLean OA; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom., Orton RJ; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom., Lemey P; Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium., Boni MF; Center for Infectious Disease Dynamics, Department of Biology, Pennsylvania State University, University Park, PA, USA., Tegally H; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine & Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Harkins GW; South African National Bioinformatics Institute, University of the Western Cape, Cape Town, South Africa., Scheepers C; National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.; SA MRC Antibody Immunity Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Bhiman JN; National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.; SA MRC Antibody Immunity Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Everatt J; National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa., Amoako DG; National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa., San JE; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine & Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Giandhari J; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine & Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Sigal A; Africa Health Research Institute, Durban, South Africa., Williamson C; Institute of Infectious Disease and Molecular Medicine, Department of Pathology, University of Cape Town, Cape Town, South Africa.; Division of Medical Virology, University of Cape Town and National Health Laboratory Service, Cape Town, South Africa.; Wellcome Center for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Cape Town, South Africa., Hsiao NY; Division of Medical Virology, University of Cape Town and National Health Laboratory Service, Cape Town, South Africa., von Gottberg A; National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., De Klerk A; Institute of Infectious Diseases and Molecular Medicine, Division of Computational Biology, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa., Shafer RW; Division of Infectious Diseases, Department of Medicine, Stanford University, Stanford, CA, USA., Robertson DL; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, United Kingdom., Wilkinson RJ; Wellcome Center for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Cape Town, South Africa.; Francis Crick Institute, London, United Kingdom.; Department of Infectious Diseases, Imperial College London, London, United Kingdom., Sewell BT; Structural Biology Research Unit, Department of Integrative Biomedical Sciences, Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Lessells R; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine & Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Nekrutenko A; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA, usegalaxy.org., Greaney AJ; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Genome Sciences & Medical Scientist Training Program, University of Washington, Seattle, WA, USA., Starr TN; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Howard Hughes Medical Institute, Seattle, WA, USA., Bloom JD; Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Howard Hughes Medical Institute, Seattle, WA, USA., Murrell B; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Wilkinson E; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine & Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.; Centre for Epidemic Response and Innovation (CERI), School of Data Science, Stellenbosch University, Stellenbosch, South Africa., Gupta RK; Africa Health Research Institute, Durban, South Africa.; Cambridge Institute of Therapeutic Immunology and Infectious Diseases, University of Cambridge, Cambridge, United Kingdom., de Oliveira T; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory Medicine & Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.; Centre for Epidemic Response and Innovation (CERI), School of Data Science, Stellenbosch University, Stellenbosch, South Africa., Kosakovsky Pond SL; Institute for Genomics and Evolutionary Medicine, Department of Biology, Temple University, Philadelphia, PA, USA.

Publikováno v: Molecular biology and evolution [Mol Biol Evol] 2022 Apr 11; Vol. 39 (4).

The emergence and ongoing convergent evolution of the SARS-CoV-2 N501Y lineages.

Autor: Martin DP; Institute of Infectious Diseases and Molecular Medicine, Division Of Computational Biology, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town 7701, South Africa. Electronic address: darrenpatrickmartin@gmail.com., Weaver S; Institute for Genomics and Evolutionary Medicine, Department of Biology, Temple University, Philadelphia, PA 19122, USA., Tegally H; KwaZulu-Natal Research Innovation and Sequencing Platform, School of Laboratory Medicine & Medical Sciences, University of KwaZulu- Natal, Durban 4001, South Africa., San JE; KwaZulu-Natal Research Innovation and Sequencing Platform, School of Laboratory Medicine & Medical Sciences, University of KwaZulu- Natal, Durban 4001, South Africa., Shank SD; Institute for Genomics and Evolutionary Medicine, Department of Biology, Temple University, Philadelphia, PA 19122, USA., Wilkinson E; KwaZulu-Natal Research Innovation and Sequencing Platform, School of Laboratory Medicine & Medical Sciences, University of KwaZulu- Natal, Durban 4001, South Africa., Lucaci AG; Institute for Genomics and Evolutionary Medicine, Department of Biology, Temple University, Philadelphia, PA 19122, USA., Giandhari J; KwaZulu-Natal Research Innovation and Sequencing Platform, School of Laboratory Medicine & Medical Sciences, University of KwaZulu- Natal, Durban 4001, South Africa., Naidoo S; KwaZulu-Natal Research Innovation and Sequencing Platform, School of Laboratory Medicine & Medical Sciences, University of KwaZulu- Natal, Durban 4001, South Africa., Pillay Y; KwaZulu-Natal Research Innovation and Sequencing Platform, School of Laboratory Medicine & Medical Sciences, University of KwaZulu- Natal, Durban 4001, South Africa., Singh L; KwaZulu-Natal Research Innovation and Sequencing Platform, School of Laboratory Medicine & Medical Sciences, University of KwaZulu- Natal, Durban 4001, South Africa., Lessells RJ; KwaZulu-Natal Research Innovation and Sequencing Platform, School of Laboratory Medicine & Medical Sciences, University of KwaZulu- Natal, Durban 4001, South Africa., Gupta RK; Clinical Microbiology, University of Cambridge, Cambridge CB2 1TN, UK; Africa Health Research Institute, KwaZulu-Natal 4013, South Africa., Wertheim JO; Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA., Nekturenko A; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, State College, PA 16802, USA., Murrell B; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm 141 83, Sweden., Harkins GW; South African Medical Research Council Capacity Development Unit, South African National Bioinformatics Institute, University of the Western Cape, Bellville 7635, South Africa., Lemey P; Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven 3000, Belgium., MacLean OA; MRC-University of Glasgow Centre for Virus Research, Glasgow 12 8QQ, Scotland, UK., Robertson DL; MRC-University of Glasgow Centre for Virus Research, Glasgow 12 8QQ, Scotland, UK., de Oliveira T; KwaZulu-Natal Research Innovation and Sequencing Platform, School of Laboratory Medicine & Medical Sciences, University of KwaZulu- Natal, Durban 4001, South Africa; Department of Global Health, University of Washington, Seattle, WA 98195-4550, USA. Electronic address: tuliodna@gmail.com., Kosakovsky Pond SL; Institute for Genomics and Evolutionary Medicine, Department of Biology, Temple University, Philadelphia, PA 19122, USA. Electronic address: spond@temple.edu.

Publikováno v: Cell [Cell] 2021 Sep 30; Vol. 184 (20), pp. 5189-5200.e7. Date of Electronic Publication: 2021 Sep 07.