Zobrazeno 1 - 10
of 144
pro vyhledávání: '"MacLean, Adam L."'
Autor:
Roesch, Elisabeth, Greener, Joe G., MacLean, Adam L., Nassar, Huda, Rackauckas, Christopher, Holy, Timothy E., Stumpf, Michael P. H.
Increasing emphasis on data and quantitative methods in the biomedical sciences is making biological research more computational. Collecting, curating, processing, and analysing large genomic and imaging data sets poses major computational challenges
Externí odkaz:
http://arxiv.org/abs/2109.09973
Autor:
Rando, Halie M., MacLean, Adam L., Lee, Alexandra J., Lordan, Ronan, Ray, Sandipan, Bansal, Vikas, Skelly, Ashwin N., Sell, Elizabeth, Dziak, John J., Shinholster, Lamonica, McGowan, Lucy D'Agostino, Guebila, Marouen Ben, Wellhausen, Nils, Knyazev, Sergey, Boca, Simina M., Capone, Stephen, Qi, Yanjun, Park, YoSon, Sun, Yuchen, Mai, David, Boerckel, Joel D., Brueffer, Christian, Byrd, James Brian, Kamil, Jeremy P., Wang, Jinhui, Velazquez, Ryan, Szeto, Gregory L, Barton, John P., Goel, Rishi Raj, Mangul, Serghei, Lubiana, Tiago, Consortium, COVID-19 Review, Gitter, Anthony, Greene, Casey S.
The novel coronavirus SARS-CoV-2, which emerged in late 2019, has since spread around the world and infected hundreds of millions of people with coronavirus disease 2019 (COVID-19). While this viral species was unknown prior to January 2020, its simi
Externí odkaz:
http://arxiv.org/abs/2102.01521
Autor:
Xiong, Lingyun, Liu, Jing, Han, Seung Yub, Koppitch, Kari, Guo, Jin-Jin, Rommelfanger, Megan, Miao, Zhen, Gao, Fan, Hallgrimsdottir, Ingileif B., Pachter, Lior, Kim, Junhyong, MacLean, Adam L., McMahon, Andrew P.
Publikováno v:
In Developmental Cell 6 November 2023 58(21):2338-2358
Akademický článek
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Autor:
Suo, Miaomiao, Rommelfanger, Megan K., Chen, Yulin, Amro, Elias Moris, Han, Bing, Chen, Zhiyang, Szafranski, Karol, Chakkarappan, Sundaram Reddy, Boehm, Bernhard O., MacLean, Adam L., Rudolph, K. Lenhard *
Publikováno v:
In Blood 28 April 2022 139(17):2653-2665
Autor:
MacLean, Adam L.
Modelling haematopoietic stem cells (HSCs) mathematically allows us to probe their behaviour, test hypotheses and make predictions. HSCs are essential and elusive; despite many recent advances much remains unknown, including how the microenvironment
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.656648
There has been a long-standing and at times fractious debate whether complex and large systems can be stable. In ecology, the so-called `diversity-stability debate' arose because mathematical analyses of ecosystem stability were either specific to a
Externí odkaz:
http://arxiv.org/abs/1505.02920
The last decade has seen an explosion in models that describe phenomena in systems medicine. Such models are especially useful for studying signaling pathways, such as the Wnt pathway. In this chapter we use the Wnt pathway to showcase current mathem
Externí odkaz:
http://arxiv.org/abs/1502.01902
The canonical Wnt signaling pathway, mediated by $\beta$-catenin, is crucially involved in development, adult stem cell tissue maintenance and a host of diseases including cancer. We undertake analysis of different mathematical models of Wnt from the
Externí odkaz:
http://arxiv.org/abs/1409.0269
Akademický článek
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