Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3)

Autor: Logie, Lisa, Van Aalten, Lidy, Knebel, Axel, Force, Thomas, Hastie, C. James, MacLauchlan, Hilary, Campbell, David G., Gourlay, Robert, Prescott, Alan, Davidson, Jane, Fuller, Will, Sutherland, Calum

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports

Glycogen synthase kinase-3 (GSK3) regulates many physiological processes through phosphorylation of a diverse array of substrates. Inhibitors of GSK3 have been generated as potential therapies in several diseases, however the vital role GSK3 plays in

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https://eprints.gla.ac.uk/160174/1/160174.pdf

Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3).

Autor: Logie L; Division of Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Van Aalten L; Division of Molecular and Clinical Medicine, University of Dundee, Dundee, UK., Knebel A; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK., Force T; Department of Cardiovascular Medicine, Vanderbilt University, Tennessee, TN, USA., Hastie CJ; Division of Signal Transduction and Therapy, University of Dundee, Dundee, UK., MacLauchlan H; Division of Signal Transduction and Therapy, University of Dundee, Dundee, UK., Campbell DG; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK., Gourlay R; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK., Prescott A; College of Life Sciences, University of Dundee, Dundee, UK., Davidson J; Division of Cancer, University of Dundee, Dundee, UK., Fuller W; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK., Sutherland C; Division of Molecular and Clinical Medicine, University of Dundee, Dundee, UK. c.d.sutherland@dundee.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2017 Dec 15; Vol. 7 (1), pp. 17682. Date of Electronic Publication: 2017 Dec 15.