Výsledky vyhledávání - "MacLaren, RE"

Akademický článek

Clinical Research on the Leading Causes of Severe Sight Impairment in the UK General and Working Populations

Autor: Liu WJ, Taylor LJ, MacLaren RE, Jolly JK

Publikováno v: Clinical Ophthalmology, Vol Volume 17, Pp 2729-2735 (2023)

Wei Jia Liu,1 Laura J Taylor,2,3 Robert E MacLaren,2,3 Jasleen K Jolly4 1School of Medicine and Biomedical Sciences, University of Oxford, Oxford, UK; 2Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK; 3Oxford Eye Hospi

Externí odkaz: https://doaj.org/article/98a4ddd518f94794a36c2a12c2626212

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Akademický článek

Rapid Quantification of the Binocular Visual Field for Clinical Trials: Performance of a Modified Esterman Supra-Threshold Test Implemented with the Open Perimetry Interface

Autor: Andrews CD, Sheldon AA, Bridge H, Downes SM, MacLaren RE, Jolly JK

Publikováno v: Clinical Ophthalmology, Vol Volume 16, Pp 1513-1523 (2022)

Colm D Andrews,1,2 Aislin A Sheldon,3 Holly Bridge,3 Susan M Downes,2,4 Robert E MacLaren,2,4 Jasleen K Jolly2– 5 1Nuffield Department of Population Health, University of Oxford, Oxford, UK; 2Oxford Eye Hospital, Oxford University Hospitals NHS Fou

Externí odkaz: https://doaj.org/article/831d83d7125740b29778514109a5e36d

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Akademický článek

Binocular Visual Function in a Pre-Presbyopic Patient with Uniocular Cataract Undergoing Cataract Surgery with a Multifocal Intraocular Lens

Autor: Wood LJ, Jolly JK, Groppe M, Benjamin L, Kirwan JF, Patel N, Elgohary MA, MacLaren RE

Publikováno v: Clinical Ophthalmology, Vol Volume 14, Pp 2001-2009 (2020)

Laura J Wood,1,2,* Jasleen K Jolly,1,2,* Markus Groppe,3 Larry Benjamin,3 James F Kirwan,4 Nishal Patel,5 Mostafa A Elgohary,6 Robert E MacLaren1,2 1Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Ox

Externí odkaz: https://doaj.org/article/368ad26409e14e3c8e863a82cc3bcf8d

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Akademický článek

Chronic central serous chorioretinopathy: long-term follow-up and vision-related quality of life

Autor: Breukink MB, Dingemans AJM, den Hollander AI, Keunen JEE, MacLaren RE, Fauser S, Querques G, Hoyng CB, Downes SM, Boon CJF

Publikováno v: Clinical Ophthalmology, Vol Volume 11, Pp 39-46 (2016)

Myrte B Breukink,1,* Alexander JM Dingemans,1,* Anneke I den Hollander,1,2 Jan EE Keunen,1 Robert E MacLaren,3,4 Sascha Fauser,5 Giuseppe Querques,6 Carel B Hoyng,1 Susan M Downes,3,4 Camiel JF Boon1,7 1Department of Ophthalmology, 2Department of Hum

Externí odkaz: https://doaj.org/article/a52fb36a3923447f9ae48fc9a53801ca

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Akademický článek

Recent advances and future prospects in choroideremia

Autor: Zinkernagel MS, MacLaren RE

Publikováno v: Clinical Ophthalmology, Vol 2015, Iss default, Pp 2195-2200 (2015)

Martin S Zinkernagel,1,2 Robert E MacLaren3,41Department of Ophthalmology, 2Department of Clinical Research, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland; 3Nuffield Laboratory of Ophthalmology, University of Oxford

Externí odkaz: https://doaj.org/article/b7f5ed9d6b8e45fd9a20dbb0562649ad

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Clinical applications of microperimetry in RPGR ‐related retinitis pigmentosa: a review

Autor: Buckley, TMW, Jolly, JK, Josan, AS, Wood, LJ, Cehajic-Kapetanovic, J, MacLaren, RE

Publikováno v: Acta Ophthalmologica. 99:819-825

Microperimetry, or fundus-tracked perimetry, is a precise static-automated perimetric technique to assess central retinal function. As visual acuity only deteriorates at a late disease stage in RPGR-related retinitis pigmentosa (RP), alternative mark

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7d61ab0738fa59e4c7bafcea1bc3cd
https://doi.org/10.1111/aos.14816

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Changes in Retinal Sensitivity Associated With Cotoretigene Toliparvovec in X-Linked Retinitis Pigmentosa With RPGR Gene Variations

Autor: von Krusenstiern, L, Liu, J, Liao, E, Gow, JA, Chen, G, Ong, T, Lotery, AJ, Jalil, A, Lam, BL, MacLaren, RE

Publikováno v: JAMA Ophthalmology. 141:275

ImportanceX-linked retinitis pigmentosa (XLRP) is a severe cause of early-onset RP in male individuals, characterized by degeneration of photoreceptors, an extinguished electroretinogram, and vision loss.ObjectiveTo assess the duration of improvement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744520734de7c8c4aaff6424f36dd384
https://doi.org/10.1001/jamaophthalmol.2022.6254

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Codon-optimized RPGR improves stability and efficacy of AAV8 gene therapy in two mouse models of X-linked retinitis pigmentosa

Autor: Fischer, MD, McClements, ME, Martinez-Fernandez de la Camara, C, Bellingrath, J-S, Dauletbekov, D, Ramsden, SC, Hickey, DG, Barnard, AR, MacLaren, RE

Publikováno v: Fischer, M D, McClements, M E, Martinez-Fernandez de la Camara, C, Bellingrath, J S, Dauletbekov, D, Ramsden, S C, Hickey, D G, Barnard, A R & MacLaren, R E 2017, ' Codon-Optimized RPGR Improves Stability and Efficacy of AAV8 Gene Therapy in Two Mouse Models of X-Linked Retinitis Pigmentosa ', Molecular Therapy . https://doi.org/10.1016/j.ymthe.2017.05.005
Molecular Therapy

X-linked retinitis pigmentosa (XLRP) is generally a severe form of retinitis pigmentosa, a neurodegenerative, blinding disorder of the retina. 70% of XLRP cases are due to mutations in the retina-specific isoform of the gene encoding retinitis pigmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b99be5314253412b32744e4178e7b69d
https://doi.org/10.1016/j.ymthe.2017.05.005

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