Zobrazeno 1 - 3
of 3
pro vyhledávání: '"MacKenzie Kinsman"'
Autor:
Cate Speake, Tania Habib, Katharina Lambert, Christian Hundhausen, Sandra Lord, Matthew J. Dufort, Samuel O. Skinner, Alex Hu, MacKenzie Kinsman, Britta E. Jones, Megan D. Maerz, Megan Tatum, Anne M. Hocking, Gerald T. Nepom, Carla J. Greenbaum, Jane H. Buckner
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
Therapeutics that inhibit IL-6 at different points in its signaling pathway are in clinical use, yet whether the immunological effects of these interventions differ based on their molecular target is unknown. We performed short-term interventions in
Externí odkaz:
https://doaj.org/article/0d42c57eea354a0694720ed4803ef101
Autor:
Jacquelyn A. Gorman, Christian Hundhausen, Mackenzie Kinsman, Tanvi Arkatkar, Eric J. Allenspach, Courtnee Clough, Samuel E. West, Kerri Thomas, Ahmet Eken, Socheath Khim, Malika Hale, Mohamed Oukka, Shaun W. Jackson, Karen Cerosaletti, Jane H. Buckner, David J. Rawlings
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
TYK2 is a JAK family member that functions downstream of multiple cytokine receptors. Genome wide association studies have linked a SNP (rs34536443) within TYK2 encoding a Proline to Alanine substitution at amino acid 1104, to protection from multipl
Externí odkaz:
https://doaj.org/article/55651875f75548a480ec57f33ff5b7cf
Autor:
Stephen P. Evanko, Rebecca Rawlings, Christian Hundhausen, Anya Schneider, Janice Chen, Thomas N. Wight, Mackenzie Kinsman, S. Alice Long, Karen Cerosaletti, Alena Roth, Elizabeth Whalen, Shan Wei, Jane H. Buckner, Carla J. Greenbaum
Publikováno v:
Science translational medicine. 8(356)
Interleukin-6 (IL-6) is a key pathogenic cytokine in multiple autoimmune diseases including rheumatoid arthritis and multiple sclerosis, suggesting that dysregulation of the IL-6 pathway may be a common feature of autoimmunity. The role of IL-6 in ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea86a48ed71502e7f078855c571351d2
https://pubmed.ncbi.nlm.nih.gov/28164101
https://pubmed.ncbi.nlm.nih.gov/28164101