Evaluation of the antibacterial and inhibitory activity of the MepA efflux pump of Staphylococcus aureus by riparins I, II, III, and IV.

Autor: Rodrigues Dos Santos Barbosa C; Biological Chemistry, Department of Biological Chemistry, Cariri Regional University (URCA), Crato, CE, Brazil. Electronic address: cristinase75@gmail.com., Macêdo NS; Biological Chemistry, Department of Biological Chemistry, Cariri Regional University (URCA), Crato, CE, Brazil. Electronic address: naiirmacedo@gmail.com., de Sousa Silveira Z; Biological Chemistry, Department of Biological Chemistry, Cariri Regional University (URCA), Crato, CE, Brazil. Electronic address: zildenesousa15@gmail.com., Rocha JE; Biological Chemistry, Department of Biological Chemistry, Cariri Regional University (URCA), Crato, CE, Brazil. Electronic address: janainaesmeraldo@gmail.com., Freitas TS; Biological Chemistry, Department of Biological Chemistry, Cariri Regional University (URCA), Crato, CE, Brazil. Electronic address: thiagocrato@hotmail.com., Muniz DF; Biological Chemistry, Department of Biological Chemistry, Cariri Regional University (URCA), Crato, CE, Brazil. Electronic address: deehmuniz78@gmail.com., Araújo IM; Biological Chemistry, Department of Biological Chemistry, Cariri Regional University (URCA), Crato, CE, Brazil. Electronic address: isaac.moura@urca.br., Datiane de Morais Oliveira-Tintino C; Laboratory of Microbiology and Molecular Biology (LMBM), Cariri Regional University (URCA), Crato, CE, Brazil. Electronic address: datianemorais@hotmail.com., Marinho ES; State University of Ceará, Graduate Program in Natural Sciences, Laboratory of Natural Products Chemistry, Fortaleza, Ceará, Brazil. Electronic address: emmanuel.marinho@uece.br., Nunes da Rocha M; State University of Ceará, Graduate Program in Natural Sciences, Laboratory of Natural Products Chemistry, Fortaleza, Ceará, Brazil. Electronic address: nunes.rocha@aluno.uece.br., Marinho MM; Center of Exact Sciences and Technology, State University of Ceará, Fortaleza, CE, Brazil. Electronic address: marinho.marcia@gmail.com., Bezerra AH; Department of Biological Sciences, Cariri Regional University (URCA), Crato, CE, Brazil. Electronic address: henriquebezerra.urca@gmail.com., Ribeiro de Sousa G; Natural and Synthetic Bioactive Products, Federal University of Paraiba (UFPB), João Pessoa, PB, Brazil. Electronic address: grsousafarm@gmail.com., Barbosa-Filho JM; Natural and Synthetic Bioactive Products, Federal University of Paraiba (UFPB), João Pessoa, PB, Brazil. Electronic address: barbosa.ufpb@gmail.com., de Souza-Ferrari J; Department of Chemistry, Federal University of Paraiba (UFPB), João Pessoa, PB, Brazil. Electronic address: jferrari@quimica.ufpb.br., Melo Coutinho HD; Laboratory of Microbiology and Molecular Biology (LMBM), Cariri Regional University (URCA), Crato, CE, Brazil. Electronic address: hdmcoutinho@urca.br., Silva Dos Santos H; Rede Nordeste de Biotecnologia (RENORBIO-Nucleadora UECE), Universidade Estadual Vale do Acaraú (UVA), Sobral, CE, Brazil. Electronic address: helciodossantos@gmail.com., Bezerra da Cunha FA; Semiarid Bioprospecting Laboratory (LABSEMA), Regional University of Cariri (URCA), Crato, CE, Brazil. Electronic address: cunha.urca@gmail.com.

Publikováno v: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2023 Oct 15; Vol. 748, pp. 109782. Date of Electronic Publication: 2023 Oct 13.

Inhibition of Staphylococcus aureus Efflux Pump by O-Eugenol and Its Toxicity in Drosophila melanogaster Animal Model.

Autor: Macêdo NS; Graduate Program in Biological Sciences-PPGCB, Federal University of Pernambuco-UFPE, Recife, PE, Brazil., de Sousa Silveira Z; Graduate Program in Biological Sciences-PPGCB, Federal University of Pernambuco-UFPE, Recife, PE, Brazil., Cordeiro PPM; Laboratory of Semi-Arid Bioprospecting (LABSEMA), Regional University of Cariri-URCA, Crato, CE, Brazil., Coutinho HDM; Laboratory of Microbiology and Molecular Biology (LMBM), Regional University of Cariri-URCA, Crato, CE, Brazil., Júnior JPS; Laboratory of Microorganism Genetics (LGM), Department of Molecular Biology, Federal University of Paraiba-UFPB, Brazil., Júnior LJQ; Laboratory of Neuroscience and Pharmacological Tests-LANEF, Federal University of Sergipe, Aracaju, SE, Brazil., Siyadatpanah A; Ferdows Paramedical School, Birjand University of Medical Sciences, Birjand, Iran., Kim B; Department of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea., da Cunha FAB; Laboratory of Semi-Arid Bioprospecting (LABSEMA), Regional University of Cariri-URCA, Crato, CE, Brazil., da Silva MV; Graduate Program in Biological Sciences-PPGCB, Federal University of Pernambuco-UFPE, Recife, PE, Brazil.

Publikováno v: BioMed research international [Biomed Res Int] 2022 Jul 19; Vol. 2022, pp. 1440996. Date of Electronic Publication: 2022 Jul 19 (Print Publication: 2022).

Evaluation of isoeugenol in inhibition of Staphylococcus aureus efflux pumps and their toxicity using Drosophila melanogaster model.

Autor: de Sousa Júnior DL; Semiarid Bioprospecting Laboratory, Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil., Cordeiro PPM; Semiarid Bioprospecting Laboratory, Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil., Dos Santos Barbosa CR; Semiarid Bioprospecting Laboratory, Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil., Muniz DF; Microbiology and Molecular Biology Laboratory, Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil., de Sousa Silveira Z; Graduate Program in Biological Sciences, Federal University of Pernambuco, Recife, Brazil., Macêdo NS; Graduate Program in Biological Sciences, Federal University of Pernambuco, Recife, Brazil., de Lacerda Neto LJ; Semiarid Bioprospecting Laboratory, Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil., de Freitas TS; Simulation and Molecular Spectroscopy Laboratory, Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil., Dos Santos JFS; Semiarid Bioprospecting Laboratory, Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil., Coutinho HDM; Microbiology and Molecular Biology Laboratory, Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil. Electronic address: hdmcoutinho@urca.br., de Oliveira LCC; Semiarid Bioprospecting Laboratory, Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil., da Cunha FAB; Semiarid Bioprospecting Laboratory, Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil.

Publikováno v: Life sciences [Life Sci] 2021 Nov 15; Vol. 285, pp. 119940. Date of Electronic Publication: 2021 Sep 09.

Effect of terpinolene against the resistant Staphylococcus aureus strain, carrier of the efflux pump QacC and β-lactamase gene, and its toxicity in the Drosophila melanogaster model.

Autor: Scherf JR; Laboratory of Bioprospecting in the Semi-Arid and Alternative Methods (LABSEMA), Regional University of Cariri - URCA, Crato, 63105-000, CE, Brazil; Biological Chemistry Pos Graduate Program, Brazil. Electronic address: jackelyne_scherf@yahoo.com.br., Barbosa Dos Santos CR; Laboratory of Bioprospecting in the Semi-Arid and Alternative Methods (LABSEMA), Regional University of Cariri - URCA, Crato, 63105-000, CE, Brazil; Biological Chemistry Pos Graduate Program, Brazil. Electronic address: cristinase75@gmail.com., Sampaio de Freitas T; Laboratory of Simulations and Molecular Spectroscopy, Regional University of Cariri - URCA, Crato, 63105-000, CE, Brazil; Biological Chemistry Pos Graduate Program, Brazil. Electronic address: thiagocrato@hotmail.com., Rocha JE; Laboratory of Microbiology and Molecular Biology (LMBM), Regional University of Cariri - URCA, Crato, 63105-000, CE, Brazil; Biological Chemistry Pos Graduate Program, Brazil. Electronic address: janainaesmeraldo@gmail.com., Macêdo NS; Laboratory of Bioprospecting in the Semi-Arid and Alternative Methods (LABSEMA), Regional University of Cariri - URCA, Crato, 63105-000, CE, Brazil; Biological Sciences Pos Graduate Program - PPGCB, Federal University of Pernambuco - UFPE, Recife, 50670-901, PE, Brazil. Electronic address: naiirmacedo@gmail.com., Mascarenhas Lima JN; Laboratory of Bioprospecting in the Semi-Arid and Alternative Methods (LABSEMA), Regional University of Cariri - URCA, Crato, 63105-000, CE, Brazil. Electronic address: jessyca.lima@urca.br., Melo Coutinho HD; Laboratory of Microbiology and Molecular Biology (LMBM), Regional University of Cariri - URCA, Crato, 63105-000, CE, Brazil., Bezerra da Cunha FA; Laboratory of Bioprospecting in the Semi-Arid and Alternative Methods (LABSEMA), Regional University of Cariri - URCA, Crato, 63105-000, CE, Brazil. Electronic address: cunha.urca@gmail.com.

Publikováno v: Microbial pathogenesis [Microb Pathog] 2020 Dec; Vol. 149, pp. 104528. Date of Electronic Publication: 2020 Sep 28.

Evaluation of the Antibacterial Activity and Efflux Pump Reversal of Thymol and Carvacrol against Staphylococcus aureus and Their Toxicity in Drosophila melanogaster .

Autor: Sousa Silveira Z; Laboratory of Semi-Arid Bioprospecting (LABSEMA), Regional University of Cariri-URCA, Crato 63105-000, CE, Brazil.; Graduate Program in Biological Sciences-PPGCB, Federal University of Pernambuco-UFPE, Recife 50670-901, PE, Brazil., Macêdo NS; Laboratory of Semi-Arid Bioprospecting (LABSEMA), Regional University of Cariri-URCA, Crato 63105-000, CE, Brazil.; Graduate Program in Biological Sciences-PPGCB, Federal University of Pernambuco-UFPE, Recife 50670-901, PE, Brazil., Sampaio Dos Santos JF; Laboratory of Semi-Arid Bioprospecting (LABSEMA), Regional University of Cariri-URCA, Crato 63105-000, CE, Brazil., Sampaio de Freitas T; Laboratory of Microbiology and Molecular Biology (LMBM), Regional University of Cariri-URCA, Crato 63105-000, CE, Brazil., Rodrigues Dos Santos Barbosa C; Laboratory of Microbiology and Molecular Biology (LMBM), Regional University of Cariri-URCA, Crato 63105-000, CE, Brazil., Júnior DLS; Laboratory of Semi-Arid Bioprospecting (LABSEMA), Regional University of Cariri-URCA, Crato 63105-000, CE, Brazil., Muniz DF; Laboratory of Microbiology and Molecular Biology (LMBM), Regional University of Cariri-URCA, Crato 63105-000, CE, Brazil., Castro de Oliveira LC; Laboratory of Semi-Arid Bioprospecting (LABSEMA), Regional University of Cariri-URCA, Crato 63105-000, CE, Brazil., Júnior JPS; Laboratory of Microorganism Genetics (LGM), Federal University of Paraiba-UFPB, João Pessoa 58051-900, PB, Brazil., Cunha FABD; Laboratory of Semi-Arid Bioprospecting (LABSEMA), Regional University of Cariri-URCA, Crato 63105-000, CE, Brazil., Melo Coutinho HD; Laboratory of Microbiology and Molecular Biology (LMBM), Regional University of Cariri-URCA, Crato 63105-000, CE, Brazil., Balbino VQ; Graduate Program in Biological Sciences-PPGCB, Federal University of Pernambuco-UFPE, Recife 50670-901, PE, Brazil., Martins N; Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2020 Apr 30; Vol. 25 (9). Date of Electronic Publication: 2020 Apr 30.