Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mabrouka Maamra"'
Autor:
Jixin Qu, Adithya Nair, George W. Muir, Kate A. Loveday, Zidi Yang, Ehsan Nourafkan, Emma N. Welbourne, Mabrouka Maamra, Mark J. Dickman, Zoltán Kis
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 4, Pp 102333- (2024)
Oligo-deoxythymidine (oligo-dT) ligand-based affinity chromatography is a robust method for purifying mRNA drug substances within the manufacturing process of mRNA-based products, including vaccines and therapeutics. However, the conventional batch m
Externí odkaz:
https://doaj.org/article/8be6ca0992cd4e1c8d99198ff00e1cbb
Autor:
Linghong Huang, Helene Bon, Mabrouka Maamra, Toby Holmes, John Atkinson, Katharine Cain, Jeff Kennedy, Catherine Kettleborough, David Matthews, Breda Twomey, Jia Ni, Zhizhan Song, Philip F Watson, Timothy S Johnson
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0298864 (2024)
Fibrotic remodeling is the primary driver of functional loss in chronic kidney disease, with no specific anti-fibrotic agent available for clinical use. Transglutaminase 2 (TG2), a wound response enzyme that irreversibly crosslinks extracellular matr
Externí odkaz:
https://doaj.org/article/7737e1a42d454e9d95b052f6ac871f2f
Autor:
Mohammed A. Hassan, Kaltoom Al-Sakkaf, Mohammed Razeeth Shait Mohammed, Ashraf Dallol, Jaudah Al-Maghrabi, Alia Aldahlawi, Sawsan Ashoor, Mabrouka Maamra, Jiannis Ragoussis, Wei Wu, Mohammad Imran Khan, Abdulrahman L. Al-Malki, Hani Choudhry
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Information regarding transcriptome and metabolome has significantly contributed to identifying potential therapeutic targets for the management of a variety of cancers. Obesity has profound effects on both cancer cell transcriptome and metabolome th
Externí odkaz:
https://doaj.org/article/0daf11510d0746fda20b1033ef08c5e2
Autor:
Mabrouka Maamra, Osama Mehdi Benayad, David Matthews, Catherine Kettleborough, John Atkinson, Katharine Cain, Helene Bon, Helen Brand, Michael Parkinson, Philip F. Watson, Timothy S. Johnson
Publikováno v:
British Journal of Pharmacology. 179:2697-2712
Transglutaminase type 2 (TG2) catalyses formation of ε-(γ-glutamyl)-lysine bonds between proteins, including those of the extracellular matrix (ECM). Elevated extracellular TG2 leads to accelerated ECM deposition and reduced clearance that underlie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ffde6501784ba28bc99a3b97d7f626
https://doi.org/10.1111/bph.15774
https://doi.org/10.1111/bph.15774
