Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mabel T. Padilla"'
Autor:
Xiuling Xu, Lang Bai, Wenshu Chen, Mabel T Padilla, Yushi Liu, Kwang Chul Kim, Steven A Belinsky, Yong Lin
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33846 (2012)
Although it is well known that epidermal growth factor receptor (EGFR) is involved in lung cancer progression, whether EGFR contributes to lung epithelial cell transformation is less clear. Mucin 1 (MUC1 in human and Muc1 in animals), a glycoprotein
Externí odkaz:
https://doaj.org/article/377effc9a0484c3a9e80afca050fa69b
Autor:
Jacek Krzeminski, Wenshu Chen, Dhimant Desai, Xiuling Xu, Mabel T. Padilla, Yong Lin, Shantu Amin
Publikováno v:
Molecular Carcinogenesis. 55:1858-1866
The interaction between epithelial and stromal cells through soluble factors such as cytokines plays an important role in carcinogenesis. Breaking this cancer-promoting interaction poses an opportunity for cancer prevention. The tumor-promoting funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f33ac59717aed8be92692798acee6ee
https://doi.org/10.1002/mc.22434
https://doi.org/10.1002/mc.22434
Autor:
Mabel T. Padilla, Toru Nyunoya, Yong Lin, Shaoqing Shi, Lin Zhang, Qiong Wang, Jennings Xu, Jun Ho Jang, Chengguo Xing
Publikováno v:
Oncotarget
Drug resistance is a major hurdle in anticancer chemotherapy. Combined therapy using drugs with distinct mechanisms of function may increase anticancer efficacy. We have recently identified the novel chalcone derivative, chalcone-24 (Chal-24), as a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5a6c6203ad020b2b1648ce5742b71f
https://doi.org/10.18632/oncotarget.2746
https://doi.org/10.18632/oncotarget.2746
Autor:
Wenshu Chen, Julie A. Hutt, Steven A. Belinsky, Shuguang Leng, Mathewos Tessema, Kosuke Kato, Bryanna Saxton, Xiuling Xu, Kwang Chul Kim, Mabel T. Padilla, Yong Lin
Mucin 1 (MUC1) is a tumor antigen that is aberrantly overexpressed in various cancers, including lung cancer. Our previous in vitro studies showed that MUC1 facilitates carcinogen-induced EGFR activation and transformation in human lung bronchial epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7697e0e5467c37ff7134d603abe4ff25
https://europepmc.org/articles/PMC5862300/
https://europepmc.org/articles/PMC5862300/
Autor:
Bilan Li, Mabel T. Padilla, Toru Nyunoya, Xiuling Xu, Xia Wang, Weiyang He, Yong Lin, Qiong Wang, Shantu Amin, Wenshu Chen, Jun Ho Jang
Publikováno v:
Carcinogenesis. 34:2119-2128
Cell survival signaling is important for the malignant phenotypes of cancer cells. Although the role of receptor-interacting protein 1 (RIP1) in cell survival signaling is well documented, whether RIP1 is directly involved in cancer development has n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca17b426f697482949d299922b7370b5
https://doi.org/10.1093/carcin/bgt143
https://doi.org/10.1093/carcin/bgt143
Publikováno v:
Bio-protocol. 4(20)
(Abstract) In cigarette smoke-induced and inflammation-associated lung cancer development, cigarette smoke extract (CSE) activates tumor necrosis factor-alpha (TNF-α) secretion from macrophages. TNF-α converting enzyme (TACE), also known as α-Secr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308f92b29bbb874d6e04397f8678d3e5
https://pubmed.ncbi.nlm.nih.gov/27284550
https://pubmed.ncbi.nlm.nih.gov/27284550
Autor:
Xiuling Xu, Weiyang He, Yong Lin, Qiong Wang, Xin Gou, Jennings Xu, Mabel T. Padilla, Guosheng Ren
Publikováno v:
Autophagy. 8:1811-1821
Although it is known that tumor necrosis factor-related apoptosis-inducing ligand (TNFSF10/TRAIL) induces autophagy, the mechanism by which autophagy is activated by TNFSF10 is still elusive. In this report, we show evidence that TRAF2- and RIPK1-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96cb347be413efbe2f799083f2dcddb2
https://doi.org/10.4161/auto.22145
https://doi.org/10.4161/auto.22145
Autor:
Wenshu, Chen, Mabel T, Padilla, Xiuling, Xu, Dhimant, Desai, Jacek, Krzeminski, Shantu, Amin, Yong, Lin
Publikováno v:
Molecular carcinogenesis. 55(11)
The interaction between epithelial and stromal cells through soluble factors such as cytokines plays an important role in carcinogenesis. Breaking this cancer-promoting interaction poses an opportunity for cancer prevention. The tumor-promoting funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e82cb3bac1b4ebae0923b7d76d393f0e
https://pubmed.ncbi.nlm.nih.gov/26609631
https://pubmed.ncbi.nlm.nih.gov/26609631
Publikováno v:
Carcinogenesis. 35(11)
Acquired chemoresistance is a major challenge in cancer therapy. While the oncoprotein Mucin-1 (MUC1) performs multiple roles in the development of diverse human tumors, whether MUC1 is involved in acquired chemoresistance has not been determined. Us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28868e7a73f3ec6c2f3a7cd37f65715c
https://pubmed.ncbi.nlm.nih.gov/25085901
https://pubmed.ncbi.nlm.nih.gov/25085901
Autor:
Mabel T. Padilla, Qiong Wang, Shaoqing Shi, Lang Bai, Amy Lin, Xia Wang, Wenshu Chen, Wenjie Chen, Yong Lin
Although receptor-interacting protein 1 (RIP1) is well known as a key mediator in cell survival and death signaling, whether RIP1 directly contributes to chemotherapy response in cancer has not been determined. In this report, we found that, in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6659aa5beb9db48751e8dbd14fd2d0e8
https://europepmc.org/articles/PMC3937640/
https://europepmc.org/articles/PMC3937640/