Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Mabel Perez-Oquendo"'
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Akademický článek
A structured curriculum supporting biomedical trainees’ transition into independent academic positions and early career success
Autor: Mabel Perez-Oquendo, Gabriele Romano, David P. Farris, Varsha Gandhi, Ignacio I. Wistuba, Robert E. Tillman, Ryan Udan, Paolo Mangahas, Rama Soundararajan
Publikováno v: BMC Medical Education, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract The United States government makes a substantial investment in biomedical training programs each year. However, for most trainees, these opportunities do not translate into career progression in academic research pathways. Only about one-fif
Externí odkaz: https://doaj.org/article/5cff586dbc0344188e10aa42c9cb42e6
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ZEB1 is Regulated by K811 Acetylation to Promote Stability, NuRD Complex Interactions, EMT, and NSCLC Metastasis
Autor: Mabel Perez-Oquendo, Roxsan Manshouri, Yanhua Tian, Jared J. Fradette, B. Leticia Rodriguez, Samrat T. Kundu, Don L. Gibbons
Publikováno v: Molecular Cancer Research. :OF1-OF16
Epithelial-to-mesenchymal transition results in loss of specialized epithelial cell contacts and acquisition of mesenchymal invasive capacity. The transcription repressor zinc finger E-box-binding homeobox 1 (ZEB1) binds to E-boxes of gene promoter r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef9fd47ed40eeb3e8b97b12af14c07ab
https://doi.org/10.1158/1541-7786.mcr-22-0503
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Supplementary Figures 1-8 from ZEB1 is Regulated by K811 Acetylation to Promote Stability, NuRD Complex Interactions, EMT, and NSCLC Metastasis
Autor: Don L. Gibbons, Samrat T. Kundu, B. Leticia Rodriguez, Jared J. Fradette, Yanhua Tian, Roxsan Manshouri, Mabel Perez-Oquendo
S1. K811 acetylation is integral to ZEB1 molecular weight. S2. &tilde225 kDa ZEB1 band regulates protein stability. S3. K811 acetylation facilitates ZEB1/NuRD interaction. S4. K811 acetylation directs the ZEB1/NuRD complex to bind at genomic promoter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e406c66c9ee67e6de59c5ba8a1b328
https://doi.org/10.1158/1541-7786.23268837.v1
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Data from ZEB1 is Regulated by K811 Acetylation to Promote Stability, NuRD Complex Interactions, EMT, and NSCLC Metastasis
Autor: Don L. Gibbons, Samrat T. Kundu, B. Leticia Rodriguez, Jared J. Fradette, Yanhua Tian, Roxsan Manshouri, Mabel Perez-Oquendo
Epithelial-to-mesenchymal transition results in loss of specialized epithelial cell contacts and acquisition of mesenchymal invasive capacity. The transcription repressor zinc finger E-box-binding homeobox 1 (ZEB1) binds to E-boxes of gene promoter r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a95618c271d71f30f529f1ca5c31924
https://doi.org/10.1158/1541-7786.c.6672897
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10
CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas
Autor: Kylee J. Veazey, Hieu T. Van, Donghang Cheng, Han Xu, Mabel Perez-Oquendo, Mark T. Bedford, Michael R. Green, Oscar D. Villarreal, Sabrina A. Stratton, Guozhen Gao, Yue Lu, Kevin Lin, Margarida A. Santos
Publikováno v: Leukemia
Somatic mutations affecting CREBBP and EP300 are a hallmark of diffuse large B-cell lymphoma (DLBCL). These mutations are frequently monoallelic, within the histone acetyltransferase (HAT) domain and usually mutually exclusive, suggesting that they m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332978e8280688988d126ac921ba9a5f
https://doi.org/10.1038/s41375-020-0908-8
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